General information for g13028.t5
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative aldehyde dehydrogenase family 7 member A1-like protein.
Parent gene
- The parent gene g13028 is located on chr_1: 27589461..27590538 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g13028 | g13028.t5 | TTS | g13028.t5 | 27588380 | 27588380 |
| chr_1 | g13028 | g13028.t5 | isoform | g13028.t5 | 27588420 | 27590520 |
| chr_1 | g13028 | g13028.t5 | exon | g13028.t5.exon1 | 27588420 | 27588574 |
| chr_1 | g13028 | g13028.t5 | cds | g13028.t5.CDS1 | 27588420 | 27588574 |
| chr_1 | g13028 | g13028.t5 | exon | g13028.t5.exon2 | 27588629 | 27588865 |
| chr_1 | g13028 | g13028.t5 | cds | g13028.t5.CDS2 | 27588629 | 27588865 |
| chr_1 | g13028 | g13028.t5 | exon | g13028.t5.exon3 | 27588930 | 27589095 |
| chr_1 | g13028 | g13028.t5 | cds | g13028.t5.CDS3 | 27588930 | 27589095 |
| chr_1 | g13028 | g13028.t5 | exon | g13028.t5.exon4 | 27589156 | 27590146 |
| chr_1 | g13028 | g13028.t5 | cds | g13028.t5.CDS4 | 27589156 | 27590142 |
| chr_1 | g13028 | g13028.t5 | exon | g13028.t5.exon5 | 27590464 | 27590520 |
| chr_1 | g13028 | g13028.t5 | TSS | g13028.t5 | 27590538 | 27590538 |
Sequences
>g13028.t5 Gene=g13028 Length=1606
GAAGTAAGTAGTTACAGTAAAATATCAACCAAATAATCAGTTGATTACCAAAAACGAAGC
AATGTCATCGTCACGTTATCTCATTGATGATCCAAATTTTTCTTTCCTAAAAGAGCTCGG
ATTAGAACGAGTAAACAAAGGAGTTTATAATGGCGAATGGTGCGGTAGTGGTGAGCTATC
AAAATCTATTGATCCAGCAACAAACGAGGTTATCGCTGAAGTTCAAAATGGAAGTGTTGA
TGATCTTGAAAGTTGCATAAAAACAGCTGAAGATGCATACAAACATTGGAGAAATATGCC
AGCTCCATTTAGAGGTGAAATTGTGAGACAAATTGGTGATGAATTGAGAAAATATCGTGA
ACCACTTGGTAAACTTGTTTCACTCGAAATGGGAAAAATTCAAGCTGAAGGGATTGGTGA
AGTTCAGGAGTTTATCGACATTTGTGACTACGCAACTGGCTTATCACGAATGTTTGCTGG
TCAAATCTTACCATCAGAACGCAATCAACATGTGATTATTGAAAAATGGAATCCACTTGG
AATTGTTGGTATCATTTCAGCATTTAATTTTCCTAATGCAGTCTTTGGATGGAATGCTGC
TATTGCTTTAGCAGTGGGAAATGTCTCTCTATGGAAAGGTGCACCATCAACTCCTCTTGT
ATCAATTGCAACAACAAAAATTGTCACTGAAGTCCTTAAACGCAATAATTTACCACCGAC
TATTACTTTATGCCAAGGAGGAACTGAAGTTGGTAAAAAATTAGTTGCTGATAAACGTGT
GAAACTTGTTTCATTCACTGGCAGTTCAAAAGTCGGTCAAGAAGTTGGTGTTGAAGTACA
AAAGAGATTTGGTAAATTGATTCTTGAATTAGGTGGCAACAATGCACTCATTATTAATGA
TGATGCCGATTTTGATATGGCACTTGATGCTGCATTCTTTGGATGTATTGGAACAGCTGG
ACAAAGATGCACAACAACAAGAAGATTGATTATTCATGAAAAACTTTATGATGCTTTCTT
ACAGAAATTAATTGCAAGATATAAAGGACTTATGAAACGTGTCGGTCATCCATTAGATTC
ATCAACGCTTTATGGTCCACTTCATAATCAACAAGCTGTTGATAATTATAAAGCAACTAT
CGATGAAGCAGTTAAGCTTGGTGGAAAAATTGAAGTAGGAGGAAATGTGATGGAAAGACC
AGGATTCTTTGTTGAACCAACAATTGTTACAAATTTACTTCATGATTCACCAATCATTAT
GAGAGAAACTTTCGCACCAATTGTCTATGTTTTAAAAGCTAAAAATTTAGAACAAGCCAT
TGAATGGAATAATGAAGTTGATCAAGGACTTTCATCTGCACTCTTTACAAAAAATCTTGG
TTCAACATTCAAATGGATAACTGAAAATGGAAGTGATTGTGGAATTGTTAATATTAATAC
ATCTCCATCAGGTGCTGAAATCGGTGGTGCATTCGGTGGAGAAAAGCACACAGGTGGTGG
TCGTGAAAGTGGATCAGATTCATGGAAACAATATTGTCGTCGATCGACAATCACATTGAA
TTACTCTCAACAATTACCACTCGCACAAGGAATTATTTTTGAATAA
>g13028.t5 Gene=g13028 Length=514
MSSSRYLIDDPNFSFLKELGLERVNKGVYNGEWCGSGELSKSIDPATNEVIAEVQNGSVD
DLESCIKTAEDAYKHWRNMPAPFRGEIVRQIGDELRKYREPLGKLVSLEMGKIQAEGIGE
VQEFIDICDYATGLSRMFAGQILPSERNQHVIIEKWNPLGIVGIISAFNFPNAVFGWNAA
IALAVGNVSLWKGAPSTPLVSIATTKIVTEVLKRNNLPPTITLCQGGTEVGKKLVADKRV
KLVSFTGSSKVGQEVGVEVQKRFGKLILELGGNNALIINDDADFDMALDAAFFGCIGTAG
QRCTTTRRLIIHEKLYDAFLQKLIARYKGLMKRVGHPLDSSTLYGPLHNQQAVDNYKATI
DEAVKLGGKIEVGGNVMERPGFFVEPTIVTNLLHDSPIIMRETFAPIVYVLKAKNLEQAI
EWNNEVDQGLSSALFTKNLGSTFKWITENGSDCGIVNINTSPSGAEIGGAFGGEKHTGGG
RESGSDSWKQYCRRSTITLNYSQQLPLAQGIIFE
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 8 | g13028.t5 | CDD | cd07130 | ALDH_F7_AASADH | 27 | 502 | 0.0 |
| 6 | g13028.t5 | Gene3D | G3DSA:3.40.605.10 | Aldehyde Dehydrogenase; Chain A | 38 | 491 | 1.4E-145 |
| 7 | g13028.t5 | Gene3D | G3DSA:3.40.309.10 | Aldehyde Dehydrogenase; Chain A | 272 | 466 | 1.4E-145 |
| 2 | g13028.t5 | PANTHER | PTHR43521:SF1 | ALPHA-AMINOADIPIC SEMIALDEHYDE DEHYDROGENASE | 23 | 511 | 2.0E-224 |
| 3 | g13028.t5 | PANTHER | PTHR43521 | ALPHA-AMINOADIPIC SEMIALDEHYDE DEHYDROGENASE | 23 | 511 | 2.0E-224 |
| 1 | g13028.t5 | Pfam | PF00171 | Aldehyde dehydrogenase family | 40 | 496 | 9.5E-131 |
| 5 | g13028.t5 | ProSitePatterns | PS00687 | Aldehyde dehydrogenases glutamic acid active site. | 268 | 275 | - |
| 4 | g13028.t5 | SUPERFAMILY | SSF53720 | ALDH-like | 25 | 503 | 1.7E-129 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016620 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | MF |
| GO:0055114 | NA | NA |
| GO:0016491 | oxidoreductase activity | MF |
KEGG
Orthology
- This transcript has been annotated with K14085 (aldehyde dehydrogenase family 7 member A1)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
