General information for g13085.t20
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Moesin/ezrin/radixin homolog 1.
Parent gene
- The parent gene g13085 is located on chr_1: 27878596..27879117 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g13085 | g13085.t20 | isoform | g13085.t20 | 27877057 | 27879056 |
| chr_1 | g13085 | g13085.t20 | exon | g13085.t20.exon1 | 27877057 | 27877400 |
| chr_1 | g13085 | g13085.t20 | cds | g13085.t20.CDS1 | 27877092 | 27877400 |
| chr_1 | g13085 | g13085.t20 | exon | g13085.t20.exon2 | 27878146 | 27878367 |
| chr_1 | g13085 | g13085.t20 | cds | g13085.t20.CDS2 | 27878146 | 27878367 |
| chr_1 | g13085 | g13085.t20 | exon | g13085.t20.exon3 | 27878432 | 27878670 |
| chr_1 | g13085 | g13085.t20 | cds | g13085.t20.CDS3 | 27878432 | 27878596 |
| chr_1 | g13085 | g13085.t20 | exon | g13085.t20.exon4 | 27878737 | 27879056 |
| chr_1 | g13085 | g13085.t20 | TTS | g13085.t20 | 27879872 | 27879872 |
| chr_1 | g13085 | g13085.t20 | TSS | g13085.t20 | NA | NA |
Sequences
>g13085.t20 Gene=g13085 Length=1125
AGAAACAGCAAGAGTACGAAGATCGCTTACGTACAATGCAAGAAGAAATCAATCGTTCAC
AAGCTAACTTAATGGAAGCTCAAGAGATGATAAGACGTTTAGAAGAGCAGTTAAAACAAT
TGCAGCTATCGAAAGATGAACTTGAGCAGCGTCAGAATGAATTGCAAGAAATGCTTACTC
GTTTGGAAGAAAGCAAAAACATGGAAGCAGCAGAACGTCAGAAATTGGAAGAAGAAATTT
CTGCAAAACAAATCGAAGTGGCCAAGATTCAAGAAGAAGTCGAAGCAAAGGATTCCGAAA
CAAGACGATTACAAGAAGAGGTTGAAGAAGCACGCCGCAAACAGCAAGAAGCAGCTGCAG
CACTTTTGGCAGCTACACAAACACCTAAACATCATCATTTGGCTGAAGATGAAAATGGAG
ATGATGATGATATGACGAATGGAGATAATGGATCTGGTGGCGGAGATGTATCAAGAGATT
TAGATACAGATATGGATATCAAAGATCCAATTGAAGATAGACGTACATTAGCTGAACGTA
ATGAAAGATTACACGATCAATTGAAGGCATTAAAACAAGATTTGGCACAATCTCGTGACG
ATACAAAAGAGACTGCCAATGATAAAATCCATAGAGAAAATGTACGTCAGGGACGTGACA
AATATAAGACATTGCGTGAAATAAGAAAAGGAAACACCAAACGTCGTGTGGATCAGTTTG
AAAACATGTAAAAAGAACATATTAACTATGATGATGTACATAAGCACTACAGCATTTAAG
AAAAAAAGATGAGCAATCAACAAAAACTTTTAGAATCAATACAATATCGTCAAGACGATT
ATTTTCATACAAAAAAAGTTAGATATCACAGCTCATTTTATGCTCATGCTTAATCTGTCG
CTTCCCAATTATCAAAGTTTTTTTTTCTATTTTTTATATTTGAATTTGCATTGTTATGAA
AGAAATTTTAAAAATAAATTCATATTTTTTCGCTTATTCGAAAGATACACACATGAGTGT
GTGTGCTGTCTTTAATCATCTTTATAGATAATGTTATATTACATATGATTATATTAAAAA
AAAAAAACATTCTTAGGCCATTATCCACTATTTCTTGATGAAATG
>g13085.t20 Gene=g13085 Length=231
MQEEINRSQANLMEAQEMIRRLEEQLKQLQLSKDELEQRQNELQEMLTRLEESKNMEAAE
RQKLEEEISAKQIEVAKIQEEVEAKDSETRRLQEEVEEARRKQQEAAAALLAATQTPKHH
HLAEDENGDDDDMTNGDNGSGGGDVSRDLDTDMDIKDPIEDRRTLAERNERLHDQLKALK
QDLAQSRDDTKETANDKIHRENVRQGRDKYKTLREIRKGNTKRRVDQFENM
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 13 | g13085.t20 | Coils | Coil | Coil | 5 | 109 | - |
| 12 | g13085.t20 | Coils | Coil | Coil | 162 | 196 | - |
| 11 | g13085.t20 | Gene3D | G3DSA:1.20.5.450 | - | 1 | 141 | 1.4E-49 |
| 10 | g13085.t20 | Gene3D | G3DSA:1.25.40.1020 | - | 150 | 231 | 1.4E-36 |
| 7 | g13085.t20 | MobiDBLite | mobidb-lite | consensus disorder prediction | 82 | 207 | - |
| 8 | g13085.t20 | MobiDBLite | mobidb-lite | consensus disorder prediction | 82 | 104 | - |
| 9 | g13085.t20 | MobiDBLite | mobidb-lite | consensus disorder prediction | 147 | 207 | - |
| 2 | g13085.t20 | PANTHER | PTHR23281:SF18 | MOESIN/EZRIN/RADIXIN HOMOLOG 1 | 1 | 231 | 2.5E-54 |
| 3 | g13085.t20 | PANTHER | PTHR23281 | MERLIN/MOESIN/EZRIN/RADIXIN | 1 | 231 | 2.5E-54 |
| 5 | g13085.t20 | PRINTS | PR00661 | ERM family signature | 186 | 207 | 1.2E-18 |
| 4 | g13085.t20 | PRINTS | PR00661 | ERM family signature | 208 | 229 | 1.2E-18 |
| 1 | g13085.t20 | Pfam | PF00769 | Ezrin/radixin/moesin family | 1 | 231 | 1.2E-66 |
| 6 | g13085.t20 | SUPERFAMILY | SSF48678 | Moesin tail domain | 150 | 231 | 3.79E-28 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0003779 | actin binding | MF |
| GO:0008092 | cytoskeletal protein binding | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
