Gene loci information

Transcript annotation

  • This transcript has been annotated as Moesin/ezrin/radixin homolog 1.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g13085 g13085.t8 TSS g13085.t8 27865974 27865974
chr_1 g13085 g13085.t8 isoform g13085.t8 27866046 27876755
chr_1 g13085 g13085.t8 exon g13085.t8.exon1 27866046 27866714
chr_1 g13085 g13085.t8 exon g13085.t8.exon2 27866963 27867178
chr_1 g13085 g13085.t8 cds g13085.t8.CDS1 27867167 27867178
chr_1 g13085 g13085.t8 exon g13085.t8.exon3 27871590 27871769
chr_1 g13085 g13085.t8 cds g13085.t8.CDS2 27871590 27871769
chr_1 g13085 g13085.t8 exon g13085.t8.exon4 27876246 27876755
chr_1 g13085 g13085.t8 cds g13085.t8.CDS3 27876246 27876755
chr_1 g13085 g13085.t8 TTS g13085.t8 NA NA

Sequences

>g13085.t8 Gene=g13085 Length=1575
AGAAATTAAGTGTATTATGTGATTATAATAATTTTTCTAAATTGTGTGCATTGGAATTTA
TAAGAATACGATGTTTATATAGTATTTATTTGCTTAATTTCATTTTAAAAAAGTATTCCA
TGCGAGATGCAAAATCATTTCGGAAGAAAGAAGGAAAAATTTTAATACACCTGCAAAAAA
GAGCAGAATGGAGAATTAGTGCTTGTTTGCGGAATAATTTCTATTCACACACACAAGATG
AGATAAAAATCTGTTTCTACATGATCTTGTGATTTGTTGAATGTTAAAAAATGACTCGTT
GTCGTCTGTCAAAAATTGTCTGATTGTACACAAAATTTCCGATTGGAAAAAAGTGAGCGA
GTGAACGTGAGAGCGAAAGACGTGTGTGAACACATAGCCAGCAGTTTTGCTTTGGTCTCT
CTCATTGACGGACGGTTGGAGTTTTCGACTTTCACAACATATTATTCTGCATTTTTGATT
AGTAGGTAATTGTACGACGACGAAGCAATAGTTGCGAATAAATACGTGCTGTGTTAAATT
ATCGTCAGCTACTAAATTGAGAATTTCTTGTTAATTAAAAAATATCACAAGTTGAAATTC
ACAAAAAATAGTTATGGTGAAGAAAAAATGAAACCGTGGCAAGTGCTTTCCTGTTGATTG
TTGTTTGTGATTTATTAATTTTGATATTCTTTTTTAAACGGAATATACAAAAATACGATA
TAAAGTCTCATCACTAGCAGCAGCAGTTCATCGCCACGAAAATCGCGAGAGAAACTTTTT
ACATTAAAAACGAAAATTACGCGATTTCTCAGTTGAATAAATAATAAATTTTCAAAGATC
CGCAGCTGAATTAAAAAAAAAAACAGAATCATCATGCCAAAATCACTAAATGTTCGCGTT
ACGACGATGGATGCAGAGTTGGAATTTGCCATCCAACAAAGCACCACAGGCAAGCAGCTT
TTCGATCAAGTTGTTAAGACAATTGGCCTTCGAGAAGTTTGGTTCTTCGGTCTTCAGTAT
ACAGATCCGAAAGGCGATTTGACATGGATTAAACTTTATAAGAAGGTGATGAGTCAAGAT
ATTCAAAAGACGGATCCATTGCAGTTCAAATTCCGTGCAAAGTTCTATCCAGAAGATGTT
GCCGAAGAGCTCATTCAGGATATTACACTTCGACTGTTTTATTTGCAAGTTAAGAATGCA
ATTTTGTCTGATGAAATTTACTGTCCGCCCGAAACTTCAGTACTTCTTGCATCATATGCC
GTTCAAGCGCGTCATGGTGATTTCAATAAAGGAACACATGGCCCTGGTTTCTTAGTAAAC
GATAGATTACTTCCACAACGCGTCATCGATCAGCATAAAATGTCGAAAGACGAATGGGAA
ACTTCTATAATTACTTGGTGGCAAGAACATCGTGGCATGTTGCGCGAAGACGCAATGATG
GAATATTTGAAAATTGCTCAGGATTTAGAGATGTATGGTGTCAATTACTTTGAAATTCGC
AATAAAAAAGGAACCGAATTATATCTTGGAGTCGATGCGTTGGGTTTGAACATTTATGAA
AAAGACGATAAACTG

>g13085.t8 Gene=g13085 Length=234
MPKSLNVRVTTMDAELEFAIQQSTTGKQLFDQVVKTIGLREVWFFGLQYTDPKGDLTWIK
LYKKVMSQDIQKTDPLQFKFRAKFYPEDVAEELIQDITLRLFYLQVKNAILSDEIYCPPE
TSVLLASYAVQARHGDFNKGTHGPGFLVNDRLLPQRVIDQHKMSKDEWETSIITWWQEHR
GMLREDAMMEYLKIAQDLEMYGVNYFEIRNKKGTELYLGVDALGLNIYEKDDKL

Protein features from InterProScan

Transcript Database ID Name Start End E.value
21 g13085.t8 CDD cd17187 FERM_F1_ERM 5 87 2.04094E-55
20 g13085.t8 CDD cd14473 FERM_B-lobe 98 198 2.19321E-33
17 g13085.t8 Gene3D G3DSA:3.10.20.90 - 4 82 6.1E-38
19 g13085.t8 Gene3D G3DSA:1.20.80.10 - 83 199 8.1E-40
18 g13085.t8 Gene3D G3DSA:2.30.29.30 - 201 234 8.0E-12
3 g13085.t8 PANTHER PTHR23281:SF18 MOESIN/EZRIN/RADIXIN HOMOLOG 1 1 234 7.9E-139
4 g13085.t8 PANTHER PTHR23281 MERLIN/MOESIN/EZRIN/RADIXIN 1 234 7.9E-139
13 g13085.t8 PRINTS PR00661 ERM family signature 17 36 9.7E-53
8 g13085.t8 PRINTS PR00935 Band 4.1 protein family signature 37 49 4.7E-30
11 g13085.t8 PRINTS PR00661 ERM family signature 69 88 9.7E-53
6 g13085.t8 PRINTS PR00935 Band 4.1 protein family signature 104 117 4.7E-30
9 g13085.t8 PRINTS PR00661 ERM family signature 113 134 9.7E-53
7 g13085.t8 PRINTS PR00935 Band 4.1 protein family signature 117 137 4.7E-30
12 g13085.t8 PRINTS PR00661 ERM family signature 159 176 9.7E-53
5 g13085.t8 PRINTS PR00935 Band 4.1 protein family signature 186 202 4.7E-30
10 g13085.t8 PRINTS PR00661 ERM family signature 209 229 9.7E-53
2 g13085.t8 Pfam PF09379 FERM N-terminal domain 9 68 2.2E-15
1 g13085.t8 Pfam PF00373 FERM central domain 93 206 5.2E-25
23 g13085.t8 ProSitePatterns PS00660 FERM domain signature 1. 58 88 -
22 g13085.t8 ProSitePatterns PS00661 FERM domain signature 2. 176 205 -
25 g13085.t8 ProSiteProfiles PS50057 FERM domain profile. 5 234 69.784
24 g13085.t8 SMART SM00295 B41_5 1 206 6.0E-81
15 g13085.t8 SUPERFAMILY SSF54236 Ubiquitin-like 2 87 2.69E-25
16 g13085.t8 SUPERFAMILY SSF47031 Second domain of FERM 89 198 6.67E-39
14 g13085.t8 SUPERFAMILY SSF50729 PH domain-like 199 233 1.6E-8

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0005856 cytoskeleton CC
GO:0008092 cytoskeletal protein binding MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values