Gene loci information

Transcript annotation

  • This transcript has been annotated as Aspartate aminotransferase, mitochondrial.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g13095 g13095.t1 TSS g13095.t1 27932619 27932619
chr_1 g13095 g13095.t1 isoform g13095.t1 27932662 27934520
chr_1 g13095 g13095.t1 exon g13095.t1.exon1 27932662 27932720
chr_1 g13095 g13095.t1 cds g13095.t1.CDS1 27932662 27932720
chr_1 g13095 g13095.t1 exon g13095.t1.exon2 27933012 27933115
chr_1 g13095 g13095.t1 cds g13095.t1.CDS2 27933012 27933115
chr_1 g13095 g13095.t1 exon g13095.t1.exon3 27933246 27933646
chr_1 g13095 g13095.t1 cds g13095.t1.CDS3 27933246 27933646
chr_1 g13095 g13095.t1 exon g13095.t1.exon4 27933765 27934253
chr_1 g13095 g13095.t1 cds g13095.t1.CDS4 27933765 27934253
chr_1 g13095 g13095.t1 exon g13095.t1.exon5 27934314 27934520
chr_1 g13095 g13095.t1 cds g13095.t1.CDS5 27934314 27934520
chr_1 g13095 g13095.t1 TTS g13095.t1 27934761 27934761

Sequences

>g13095.t1 Gene=g13095 Length=1260
ATGTCTTCTAAACTTTTGCAAAATAAAGGGTTGACAAGTATTTTAGCAACGAGATGCAGC
TCATGGTGGAGTTCTGTTCAAATGGGACCACCTGATGCAATTCTCGGTGTTACAGAAGCA
TTTAAAAAGGATACAAATCCTAAGAAGATCAACTTGGGTGTCGGCGCTTATCGCGATGAT
AATGGAAAACCTTATGTTTTACCTAGCGTTCAAAAGGCCGAAGAATTATTGGCAAAGAAA
GCTTTAGATAAAGAATATGCCCCGATTTCTGGACCTGCTGACTTTTGTAAATTGAGTATT
GAATTGGCATTGGGAGAAAGTGAAGAACTCAAAGCCGGATTGAATGCTACAGTTCAAGGA
ATTTCAGGAACTGGCTCATTGCGTGTTGGCGGCGCTTTCTTGGCAAGTTTCTTCCCTGGA
CCTAAAGAAATTTATCTGCCAACACCATCATGGGGTAATCATACACCAATTTTCAAACAC
TCAGGACTTGGTGTTAAACAGTACAAATATTACGATCCAAAAACATGTGGCTTAGACTTT
CAAGGAGCTCTGGACGACATTTCCAAAATCCCTGAACGTTCAATTATTTTGCTTCACGCT
TGTGCTCATAATCCTACTGGTGTAGACCCAACGCCAGAACAATGGCAAGAGTTATCGGCA
TTAATTAAGAAAAAGAATTTATTCCCGTACTTTGATATGGCTTATCAAGGATTCGCTAGT
GGATCAGTTGATAAAGATGCATTTGCTGTTCGATTGTTTATTCGTGATGGACATCAAATT
GCTTTGGCTCAAAGTTATGCAAAGAACATGGGTCTTTATGGAGAACGCGCTGGTGCATTT
TCACTCATTACAAGTAGTAAAGATGAGGCTGAACGTACATTATCACAACTTAAGATTCTC
ATTAGACCAATGTATTCGAATCCACCCATTCATGGTGCACGTATTGTTAGCACAATTTTA
AGTACACCCGATTTGAGATCAGAATGGTTGAAAGATGTAAAAGGAATGGCTGATCGTATT
ATTTCTGTTCGAGCAACATTGAGAAAGAATTTGGAAAATCTTGGATCAAAGAAGAATTGG
CAACACATTACCGATCAAATCGGTATGTTCTGTTTCACTGGAATGAATGCAGATCAAAGT
ACTCGTTTGTGCAACGAATTCAGCATCTATTTGACAAAAGATGGAAGAATTTCAATGGCT
GGTGTCACTTCAAAGAATGTTGAATACTTGGCTCATGGAATTCATGAAGTCACAAAGTAA

>g13095.t1 Gene=g13095 Length=419
MSSKLLQNKGLTSILATRCSSWWSSVQMGPPDAILGVTEAFKKDTNPKKINLGVGAYRDD
NGKPYVLPSVQKAEELLAKKALDKEYAPISGPADFCKLSIELALGESEELKAGLNATVQG
ISGTGSLRVGGAFLASFFPGPKEIYLPTPSWGNHTPIFKHSGLGVKQYKYYDPKTCGLDF
QGALDDISKIPERSIILLHACAHNPTGVDPTPEQWQELSALIKKKNLFPYFDMAYQGFAS
GSVDKDAFAVRLFIRDGHQIALAQSYAKNMGLYGERAGAFSLITSSKDEAERTLSQLKIL
IRPMYSNPPIHGARIVSTILSTPDLRSEWLKDVKGMADRIISVRATLRKNLENLGSKKNW
QHITDQIGMFCFTGMNADQSTRLCNEFSIYLTKDGRISMAGVTSKNVEYLAHGIHEVTK

Protein features from InterProScan

Transcript Database ID Name Start End E.value
12 g13095.t1 CDD cd00609 AAT_like 50 408 4.01923E-42
10 g13095.t1 Gene3D G3DSA:3.90.1150.10 Aspartate Aminotransferase 32 415 1.5E-171
11 g13095.t1 Gene3D G3DSA:3.40.640.10 - 66 337 1.5E-171
2 g13095.t1 PANTHER PTHR11879 ASPARTATE AMINOTRANSFERASE 9 419 1.2E-198
3 g13095.t1 PANTHER PTHR11879:SF39 ASPARTATE AMINOTRANSFERASE, MITOCHONDRIAL 9 419 1.2E-198
7 g13095.t1 PRINTS PR00799 Aspartate aminotransferase signature 196 215 1.5E-36
6 g13095.t1 PRINTS PR00799 Aspartate aminotransferase signature 227 239 1.5E-36
4 g13095.t1 PRINTS PR00799 Aspartate aminotransferase signature 295 320 1.5E-36
5 g13095.t1 PRINTS PR00799 Aspartate aminotransferase signature 363 381 1.5E-36
1 g13095.t1 Pfam PF00155 Aminotransferase class I and II 48 413 1.7E-87
9 g13095.t1 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 265 278 -
8 g13095.t1 SUPERFAMILY SSF53383 PLP-dependent transferases 21 418 5.52E-113

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0009058 biosynthetic process BP
GO:0006520 cellular amino acid metabolic process BP
GO:0008483 transaminase activity MF
GO:0003824 catalytic activity MF
GO:0030170 pyridoxal phosphate binding MF

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values