General information for g13105.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Cyclin-dependent kinase 1.
Parent gene
- The parent gene g13105 is located on chr_1: 27987634..27988657 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g13105 | g13105.t3 | TTS | g13105.t3 | 27987386 | 27987386 |
| chr_1 | g13105 | g13105.t3 | isoform | g13105.t3 | 27987411 | 27988381 |
| chr_1 | g13105 | g13105.t3 | exon | g13105.t3.exon1 | 27987411 | 27987509 |
| chr_1 | g13105 | g13105.t3 | exon | g13105.t3.exon2 | 27987572 | 27988381 |
| chr_1 | g13105 | g13105.t3 | cds | g13105.t3.CDS1 | 27987634 | 27988329 |
| chr_1 | g13105 | g13105.t3 | TSS | g13105.t3 | 27988744 | 27988744 |
Sequences
>g13105.t3 Gene=g13105 Length=909
GTTATTGAAAGAACTGAAACATCCAAATATCGTCTCTTTACAAGACGTTTTAATGGAAGA
TAGTCGACTGTATTTAATCTTTGAATTTCTCTCGATGGATCTTAAAAAATACATGGATTC
ACTGCCCTCAGAAAAGATGTTGGATACAGAATTAGTTCGAAGCTACATGTATCAAATAAC
TGCCGCAATTGTTTTTTGCCATAGACGACGAGTTTTGCATCGCGATTTGAAACCTCAAAA
TTTACTTATAAATAAGGATGGTTTAATAAAGGTAGCTGATTTTGGATTGGGTCGTTCATT
TGGGATTCCTGTCCGTAATTATACACATGAGATTGTTACACTTTGGTATCGTGCGCCAGA
AGTTTTGCTTGGCTCACAACGCTATTCATGTCCAGTTGATGTATGGTCTTTAGGATGTAT
ATTCGCTGAAATGGCTACGCGTAAGCCTCTATTCCAAGGTGATTCCGAAATAGATCAATT
ATTCCGAATGTTCAGGATTTTGAAGACACCAACAGATGATATCTGGCCAGGAGTCACACA
ATTGCCAGATTACAAACCAACATTTCCATGCTGGACACAAAACAATCTTGCTCAACATGT
CAAAAATATGGATTCAGCTGCATTTGATTTATTAAATAAAACTTTGATTTACGATCCAGC
TCTTCGCATTTCAGCAAAAGAAATGCTTGAACATAAATATTTTGATACAATCGATCGCAG
CATCATAAGCTCGATCCCTCTTCATTAATATTTAAGTGCTCTCTCACTTTATATTGACTT
TAAAGTCATTTTATCAAACATCCTATAATATTATTATTGGTATATATATTCAAAAATGAT
TTTTTCATACTATCCATTAAAACTTTCTTTTCCTCTTGTATAATTAATAACGAACGATGA
GAAAATCCA
>g13105.t3 Gene=g13105 Length=231
MEDSRLYLIFEFLSMDLKKYMDSLPSEKMLDTELVRSYMYQITAAIVFCHRRRVLHRDLK
PQNLLINKDGLIKVADFGLGRSFGIPVRNYTHEIVTLWYRAPEVLLGSQRYSCPVDVWSL
GCIFAEMATRKPLFQGDSEIDQLFRMFRILKTPTDDIWPGVTQLPDYKPTFPCWTQNNLA
QHVKNMDSAAFDLLNKTLIYDPALRISAKEMLEHKYFDTIDRSIISSIPLH
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g13105.t3 | Gene3D | G3DSA:1.10.510.10 | Transferase(Phosphotransferase) domain 1 | 15 | 226 | 6.1E-72 |
| 2 | g13105.t3 | PANTHER | PTHR24056:SF371 | CYCLIN-DEPENDENT KINASE A-2 | 4 | 226 | 1.8E-94 |
| 3 | g13105.t3 | PANTHER | PTHR24056 | CELL DIVISION PROTEIN KINASE | 4 | 226 | 1.8E-94 |
| 1 | g13105.t3 | Pfam | PF00069 | Protein kinase domain | 2 | 217 | 2.7E-51 |
| 6 | g13105.t3 | ProSitePatterns | PS00108 | Serine/Threonine protein kinases active-site signature. | 54 | 66 | - |
| 8 | g13105.t3 | ProSiteProfiles | PS50011 | Protein kinase domain profile. | 1 | 217 | 35.806 |
| 5 | g13105.t3 | SMART | SM00220 | serkin_6 | 1 | 217 | 5.7E-43 |
| 4 | g13105.t3 | SUPERFAMILY | SSF56112 | Protein kinase-like (PK-like) | 3 | 220 | 3.64E-72 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005524 | ATP binding | MF |
| GO:0004672 | protein kinase activity | MF |
| GO:0006468 | protein phosphorylation | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
