General information for g13166.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Neuropathy target esterase sws.
Parent gene
- The parent gene g13166 is located on chr_1: 28312221..28313648 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g13166 | g13166.t3 | TSS | g13166.t3 | 28307051 | 28307051 |
| chr_1 | g13166 | g13166.t3 | isoform | g13166.t3 | 28307133 | 28308868 |
| chr_1 | g13166 | g13166.t3 | exon | g13166.t3.exon1 | 28307133 | 28307231 |
| chr_1 | g13166 | g13166.t3 | cds | g13166.t3.CDS1 | 28307133 | 28307231 |
| chr_1 | g13166 | g13166.t3 | exon | g13166.t3.exon2 | 28307309 | 28307390 |
| chr_1 | g13166 | g13166.t3 | cds | g13166.t3.CDS2 | 28307309 | 28307390 |
| chr_1 | g13166 | g13166.t3 | exon | g13166.t3.exon3 | 28307525 | 28308868 |
| chr_1 | g13166 | g13166.t3 | cds | g13166.t3.CDS3 | 28307525 | 28308867 |
| chr_1 | g13166 | g13166.t3 | TTS | g13166.t3 | NA | NA |
Sequences
>g13166.t3 Gene=g13166 Length=1525
ATGGATATTGTAGGAATTATAAAGAAGAGCTATAGAAGTTATGGCTCACTATTTTCAGAT
GATTTCATTGCTTTTATTAAAGAATCATCGCAAAATCATATATGGATAACTATCATCGTA
ATACTGCTTACAACTTGTATTCTTATTGCTTGCTATCTTTGGAGAAAGAACCAATTGCGA
AAGCAATCAATTATCGATAGATTAACTGCTTCATTTCTTCATGATGGTCAAACGAGATTT
CGAAAGAGAGACAAGATGCTGTTTTATGGTCGTCGAATGTTGCGAAAGGTAAAGACCATC
AGTGGAACCGGTGGAGAGAAAGGGAGAAAGCGTAAGGCTGTAATGAAATTTGCAAAAAGA
CTTTTGCAACTGCAAAAAGAAAATATGCAACCGCAACTTAATGTCAAAGAACCACCAGCT
GAATATTTCGAAGAAATTACCGATAAAGCAGCTGATAAAGTGCCTATTGATGCCTATTTC
ATGCTACAATCTATTCGTATCTTTGGTCAATTTGAGAAACCAGTATTTTTACGAATCTGT
AAGCATACAGAAGTATTGAATCTTAAAGCTGGTGATTATCTTATTAAAATCGGAGATCCA
GATGATTCAGTTTTTATTGTGCAATCAGGACAAGTTAATGTTTTTCTTAACAATCATGAT
GGTTCATCAATTTCATTAAAAGTCGTAAAAAAAGGTGAAACAGTAACATCATTACTCAGT
TTCATTGACGTCATTGTAGGAAACGAAAGCTGCTACAAAACAGTCACTGCTAAAGCAATT
GAAGATAGTCAAGTTATTCGACTGCCAATGAAGGCTTTGCAAGAAGTCTTTAATGAAAAT
CCAGATATTTTAATTAGAGTTATTCAAGTAATTATGGTTAGATTACAAAGAATTACTATA
AGTGCCCTACACAATTATCTTGGATTAAATATTGAATATATATATGTTTCGCAGAAAAAG
AAACAAGTTCAAAATGCCGGTCTTTTGTCAAATATCGTAAAAGGCTATCAACATAAAAGA
CAAATGTCTGATCAATTTTCTCTTGTGATGACCCATGGTGTAATGAGTTCTGAACAAAAA
CCTGATATGATTAGTGACATTGATTTTCCTATACTTGTACCACGTAGAACCTCAACTATT
CCTCAACAACAACAACAACAACCCTCAGACATTCCAATTGACATTGAATTAATGAAAAGC
ATTGCTACTGATGGATTTTTGAAAGAACTTGGATTAAAAGATGATGATCGTGTATTAATT
GCTGATACTATAGAAATTAAAGAAATTTCACCTGGAACAACTTTAACTCATCAGGGAAGC
GATGACGATGTATTATTGATTTATATCATCACGGGTGGATTAACACTTTTCAATAATCAA
CCTTCGAAAGGTAGTAAGAAAACAGAAACACATTCCATTAACATTCATCCTGGAGAAGTT
GTTGGCGGATTAGCTGTTTTAACAGGAGAAAGTAGTTTATATACAATTAAATCAAGAGTT
TCTTCGAGAGTGGGTTTGATAACAA
>g13166.t3 Gene=g13166 Length=508
MDIVGIIKKSYRSYGSLFSDDFIAFIKESSQNHIWITIIVILLTTCILIACYLWRKNQLR
KQSIIDRLTASFLHDGQTRFRKRDKMLFYGRRMLRKVKTISGTGGEKGRKRKAVMKFAKR
LLQLQKENMQPQLNVKEPPAEYFEEITDKAADKVPIDAYFMLQSIRIFGQFEKPVFLRIC
KHTEVLNLKAGDYLIKIGDPDDSVFIVQSGQVNVFLNNHDGSSISLKVVKKGETVTSLLS
FIDVIVGNESCYKTVTAKAIEDSQVIRLPMKALQEVFNENPDILIRVIQVIMVRLQRITI
SALHNYLGLNIEYIYVSQKKKQVQNAGLLSNIVKGYQHKRQMSDQFSLVMTHGVMSSEQK
PDMISDIDFPILVPRRTSTIPQQQQQQPSDIPIDIELMKSIATDGFLKELGLKDDDRVLI
ADTIEIKEISPGTTLTHQGSDDDVLLIYIITGGLTLFNNQPSKGSKKTETHSINIHPGEV
VGGLAVLTGESSLYTIKSRVSSRVGLIT
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 13 | g13166.t3 | CDD | cd00038 | CAP_ED | 167 | 288 | 3.30184E-20 |
| 14 | g13166.t3 | CDD | cd00038 | CAP_ED | 411 | 504 | 4.79692E-6 |
| 9 | g13166.t3 | Gene3D | G3DSA:2.60.120.10 | Jelly Rolls | 158 | 304 | 8.7E-29 |
| 8 | g13166.t3 | Gene3D | G3DSA:2.60.120.10 | Jelly Rolls | 372 | 508 | 6.7E-8 |
| 2 | g13166.t3 | PANTHER | PTHR14226 | NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER | 104 | 385 | 5.6E-86 |
| 4 | g13166.t3 | PANTHER | PTHR14226:SF29 | NEUROPATHY TARGET ESTERASE SWS | 104 | 385 | 5.6E-86 |
| 3 | g13166.t3 | PANTHER | PTHR14226 | NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER | 407 | 508 | 5.6E-86 |
| 5 | g13166.t3 | PANTHER | PTHR14226:SF29 | NEUROPATHY TARGET ESTERASE SWS | 407 | 508 | 5.6E-86 |
| 1 | g13166.t3 | Pfam | PF00027 | Cyclic nucleotide-binding domain | 187 | 280 | 4.9E-14 |
| 11 | g13166.t3 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1 | 33 | - |
| 12 | g13166.t3 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 34 | 54 | - |
| 10 | g13166.t3 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 55 | 508 | - |
| 18 | g13166.t3 | ProSiteProfiles | PS50042 | cAMP/cGMP binding motif profile. | 167 | 294 | 14.754 |
| 17 | g13166.t3 | ProSiteProfiles | PS50042 | cAMP/cGMP binding motif profile. | 411 | 508 | 7.615 |
| 16 | g13166.t3 | SMART | SM00100 | cnmp_10 | 167 | 292 | 1.1E-11 |
| 7 | g13166.t3 | SUPERFAMILY | SSF51206 | cAMP-binding domain-like | 161 | 298 | 4.06E-25 |
| 6 | g13166.t3 | SUPERFAMILY | SSF51206 | cAMP-binding domain-like | 411 | 506 | 6.02E-8 |
| 15 | g13166.t3 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 32 | 54 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
There are no GO annotations for this transcript.
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
