General information for g13166.t4
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Neuropathy target esterase sws.
Parent gene
- The parent gene g13166 is located on chr_1: 28312221..28313648 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g13166 | g13166.t4 | isoform | g13166.t4 | 28309836 | 28312221 |
| chr_1 | g13166 | g13166.t4 | exon | g13166.t4.exon1 | 28309836 | 28310133 |
| chr_1 | g13166 | g13166.t4 | cds | g13166.t4.CDS1 | 28309852 | 28310133 |
| chr_1 | g13166 | g13166.t4 | exon | g13166.t4.exon2 | 28310193 | 28310343 |
| chr_1 | g13166 | g13166.t4 | cds | g13166.t4.CDS2 | 28310193 | 28310343 |
| chr_1 | g13166 | g13166.t4 | exon | g13166.t4.exon3 | 28310412 | 28310474 |
| chr_1 | g13166 | g13166.t4 | cds | g13166.t4.CDS3 | 28310412 | 28310474 |
| chr_1 | g13166 | g13166.t4 | exon | g13166.t4.exon4 | 28310733 | 28310849 |
| chr_1 | g13166 | g13166.t4 | cds | g13166.t4.CDS4 | 28310733 | 28310849 |
| chr_1 | g13166 | g13166.t4 | exon | g13166.t4.exon5 | 28311527 | 28312221 |
| chr_1 | g13166 | g13166.t4 | cds | g13166.t4.CDS5 | 28311527 | 28312221 |
| chr_1 | g13166 | g13166.t4 | TTS | g13166.t4 | 28312356 | 28312356 |
| chr_1 | g13166 | g13166.t4 | TSS | g13166.t4 | NA | NA |
Sequences
>g13166.t4 Gene=g13166 Length=1324
TTTGTGCCCTAAACGAATGTTTACGCGTAAAAGTCAATATCGTGTTAATGATTTATATAC
AAAAGTTTTAAACTCCGAACCAAATATTCATTCAGATTTTTCAAGACTTGCTCGATGGTT
GACAGGAAATTCTGTTGGTCTTGTTTTGGGAGGTGGTGGTGCTAGAGGTGCTGCACATGT
TGGAATGCTTAAAGCAATTCAAGAAGCATCAATTCCTATTGATATGGTTGGTGGGGTATC
AATTGGTGCTTTCATGGGGGCATTATGGTGCTCTGAACGAAATTTAACTGTTGTCACGCA
AAAGGCAAGAGAATGGTGCAAAAAGATGACACATTATGGACTACAACTTTTAGACTTGAC
ATATCCAATTACGTCAATGTTTAGTGGAAAACAGTTCAATAAAACTATTCGAGATACATT
TGGCGATAATCTCAAAATTGAAGATTTGTGGATACCATACTTCACTTTGACTACAGATAT
CACAGATAGTTGTTCACGAATCCACACTCATGGTCACCTCTGGCGCTACGTTAGGGCTAG
CATGAGTCTTTCAGGCTACATGCCTCCTCTCTGTGATCCTATCGATGGTCATCATTTACT
CGATGGAGGCTACTGCAACAATCTTCCCTCTGATGTAATGCGAGCTCAAGGAGCAAATAT
AATTATTGCCATTGATGTAGGATCTCAAGATGATACTGATTTGACAGATTATGGGGACGA
TTTGAGTGGCTGGTGGGTTTTATATAAGCGTTATAATCCATTTACAGCACCAGTAAAAGT
AATGAGTATACCAGACATACAAAGTCGATTAGCATATGTTTCATGTGTTCGTCAACTCGA
ACAAGTAAAGAACAGTGATTACTGCGAATATTTACGACCACCAATAGATAAATATAAAAC
TTTAGCATTTGGTTCATTTGATGAGATTAAAGAAGTTGGTTATGCTTATGGTAAAGCATA
CTTTGAAAATATTACTAAGAATGGTGGCATATCTAAATTCACAAAATGGTCGTTAAAGAA
AAATTCGGATGAAAGTCGTGAAACGAGTCCGATCAACCAATCAACTTATACATTCGTTGA
TTTAGCACAAATTGTCTGTAAAATTCCAGAGATATGTCAAGATAAAAATGAAGATTTATC
AAGTGAAGACGATTATTTTGCCGGATATGCCTCTGAACCATCAACTTTAAGGTCTAGTGC
AAAACCACGTCCACTCAGAACAGGCGGTTCTTTGTCATTATCTGAAAATGAATATGAGAG
TGATGACTCAATTTCAGATGCTGGTACTTCATCACCCATAAAGAAAACAAATGGTGAAAT
TTAA
>g13166.t4 Gene=g13166 Length=435
MFTRKSQYRVNDLYTKVLNSEPNIHSDFSRLARWLTGNSVGLVLGGGGARGAAHVGMLKA
IQEASIPIDMVGGVSIGAFMGALWCSERNLTVVTQKAREWCKKMTHYGLQLLDLTYPITS
MFSGKQFNKTIRDTFGDNLKIEDLWIPYFTLTTDITDSCSRIHTHGHLWRYVRASMSLSG
YMPPLCDPIDGHHLLDGGYCNNLPSDVMRAQGANIIIAIDVGSQDDTDLTDYGDDLSGWW
VLYKRYNPFTAPVKVMSIPDIQSRLAYVSCVRQLEQVKNSDYCEYLRPPIDKYKTLAFGS
FDEIKEVGYAYGKAYFENITKNGGISKFTKWSLKKNSDESRETSPINQSTYTFVDLAQIV
CKIPEICQDKNEDLSSEDDYFAGYASEPSTLRSSAKPRPLRTGGSLSLSENEYESDDSIS
DAGTSSPIKKTNGEI
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 6 | g13166.t4 | CDD | cd07225 | Pat_PNPLA6_PNPLA7 | 25 | 331 | 0.0 |
| 5 | g13166.t4 | Gene3D | G3DSA:3.40.1090.10 | Cytosolic phospholipase A2 catalytic domain | 24 | 150 | 1.4E-26 |
| 8 | g13166.t4 | MobiDBLite | mobidb-lite | consensus disorder prediction | 388 | 435 | - |
| 9 | g13166.t4 | MobiDBLite | mobidb-lite | consensus disorder prediction | 404 | 435 | - |
| 2 | g13166.t4 | PANTHER | PTHR14226 | NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER | 1 | 395 | 1.0E-167 |
| 3 | g13166.t4 | PANTHER | PTHR14226:SF23 | PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN 7 | 1 | 395 | 1.0E-167 |
| 1 | g13166.t4 | Pfam | PF01734 | Patatin-like phospholipase | 42 | 207 | 8.9E-20 |
| 7 | g13166.t4 | ProSitePatterns | PS01237 | Uncharacterized protein family UPF0028 signature. | 45 | 77 | - |
| 10 | g13166.t4 | ProSiteProfiles | PS51635 | Patatin-like phospholipase (PNPLA) domain profile. | 42 | 209 | 40.49 |
| 4 | g13166.t4 | SUPERFAMILY | SSF52151 | FabD/lysophospholipase-like | 36 | 324 | 2.62E-57 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0004622 | lysophospholipase activity | MF |
| GO:0046470 | phosphatidylcholine metabolic process | BP |
| GO:0006629 | lipid metabolic process | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
