Gene loci information

Transcript annotation

  • This transcript has been annotated as Deoxycytidylate deaminase.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g13262 g13262.t3 TSS g13262.t3 28851250 28851250
chr_1 g13262 g13262.t3 isoform g13262.t3 28851444 28852076
chr_1 g13262 g13262.t3 exon g13262.t3.exon1 28851444 28852076
chr_1 g13262 g13262.t3 cds g13262.t3.CDS1 28851461 28851922
chr_1 g13262 g13262.t3 TTS g13262.t3 28852036 28852036

Sequences

>g13262.t3 Gene=g13262 Length=633
ATTGGGAAGATTATTTCATGGGAATAGCATTTTTAGCAGCTCAGAGGAGTAAAGATCCAG
CAACACAAGTAGGAGCTTGTATTGTAAATGATGAGATGAAAATTGTTGCAATAGGATATA
ATGGTTTTCCCATAAATTGTTCTGATGATAAATTTCCATGGACAAAAGAATCTAATGATC
CATTAGAAAATAAATACATGTATGTATGTCATGCTGAAGTAAATGCTATTCTCAACAAAA
ATAGCTTCGATGTGAAAGGTTGCTCGCTTTATGTGGCTCTCTTTCCTTGCAACGAATGTG
CAAAAATCATCATTCAATCAAGAATCAAAGAAATTGTTTATTTATCAGATAAACATGCTG
ACAAACCACAAACTAAAGCTTCAAAGATGATGCTTGACTCTGCAGGTATAAAATACAGGC
AGTATAAACCTAAACACTCGAAAATTGTTATTGATTTTGATAAGATTAACGAAAATTGAC
TTTATTATGTATTCAGAAAAACTTTATAATGACGATAAAATTATTGAAGCAAAAACCAAT
ACAAAAGCTGATTGCTTAATATTATAACTTGATGATTTTTCATCAATTAATGGCAAATAT
GACCAATCAATTTTGTTTGTCTTTACAATTTCA

>g13262.t3 Gene=g13262 Length=153
MGIAFLAAQRSKDPATQVGACIVNDEMKIVAIGYNGFPINCSDDKFPWTKESNDPLENKY
MYVCHAEVNAILNKNSFDVKGCSLYVALFPCNECAKIIIQSRIKEIVYLSDKHADKPQTK
ASKMMLDSAGIKYRQYKPKHSKIVIDFDKINEN

Protein features from InterProScan

Transcript Database ID Name Start End E.value
6 g13262.t3 CDD cd01286 deoxycytidylate_deaminase 1 127 2.10037E-51
4 g13262.t3 Gene3D G3DSA:3.40.140.10 Cytidine Deaminase 1 153 4.0E-58
2 g13262.t3 PANTHER PTHR11086 DEOXYCYTIDYLATE DEAMINASE-RELATED 1 152 2.8E-73
5 g13262.t3 PIRSF PIRSF006019 dCMP_deaminase 1 146 6.3E-45
1 g13262.t3 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 1 109 1.7E-24
7 g13262.t3 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 65 98 -
8 g13262.t3 ProSiteProfiles PS51747 Cytidine and deoxycytidylate deaminases domain profile. 1 125 21.89
3 g13262.t3 SUPERFAMILY SSF53927 Cytidine deaminase-like 1 137 2.48E-33

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0004132 dCMP deaminase activity MF
GO:0016787 hydrolase activity MF
GO:0006220 pyrimidine nucleotide metabolic process BP
GO:0008270 zinc ion binding MF
GO:0003824 catalytic activity MF

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values