General information for g13335.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Prestin.
Parent gene
- The parent gene g13335 is located on chr_1: 29363552..29365635 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g13335 | g13335.t1 | TSS | g13335.t1 | 29363411 | 29363411 |
| chr_1 | g13335 | g13335.t1 | isoform | g13335.t1 | 29363552 | 29365635 |
| chr_1 | g13335 | g13335.t1 | exon | g13335.t1.exon1 | 29363552 | 29363696 |
| chr_1 | g13335 | g13335.t1 | cds | g13335.t1.CDS1 | 29363552 | 29363696 |
| chr_1 | g13335 | g13335.t1 | exon | g13335.t1.exon2 | 29363753 | 29365635 |
| chr_1 | g13335 | g13335.t1 | cds | g13335.t1.CDS2 | 29363753 | 29365635 |
| chr_1 | g13335 | g13335.t1 | TTS | g13335.t1 | NA | NA |
Sequences
>g13335.t1 Gene=g13335 Length=2028
ATGCCAGCAAGAATTTTTAAAAACAACATAATCGACATATGTGAGACAAAACCTCGCGTG
ACTATTCCTTATACAGTCACAAGAAATGTGTTCAAGCAAGAAGAACTCGAACAGATTGCT
GGATACGATCGTCACAAAGATACGCCATCTGAAAGCATTCGTGACAATCTTAAAAAATTG
AAGCCGAAAAATTTAATTTATGAGTTATGTCCTGTGTTGAAATGGCTTCCAGAATATCCA
ATAAAAGCGAATTTATTTGGAGACCTTATATCAGGATTTACAGTTGCTATAATGCATATT
CCACAAGGTATGGCTTACGGTTTACTTGCTGGTGTTGATCCAATTGTTGGTCTGTACATG
GCATTCTTTCCTACTTTAATTTATTTTTTATTCGGCACATCGAGACATGTCAGTATGGGA
ACTTTTGCAATTGTCTCAATTATGACATCAAAAATTGTTTCAACTTATGCAGATCCTAAT
TATGGCAATACAAATCTAAATTCAACGAATGATGAACCATTGGATCAATTGCCTTATTAT
CATTACACTCCATTTCAAGTTGCAACAGCAGTTTCAATGGTTTGTGGCTTCTATCAAATT
ATCATGTGTGTGCTTCGTCTTGGAATACTTTCATCACTTTTATCTGAAGCACTTGTCAAT
GGCTTCACAACAGCAGCTGCAGTGCATGTGCTTGTCTCACAATTGAAAGATATTTTAGGC
TTGAGACTTCCACGCCATCAGGGTGCATTTAAAATAATTTTATCTCTTCGTGACATCATC
TTAAATATTCCGAGAGCAAATGTTTACGCCATTTATATCGCAATAGTTTGCATCGCATTT
ATGGTAGTTATGAATGAATTTGTAAAACCTTGGGTAGCTAAAAGGTGCAAATTTCCTATT
CCAACTGAATTAATAGCTGTTGTTGGTTTTACTGTAATATCTTTTGCTTTGAATCTTGGT
GGATCAAAGTATAAAGTTAGAGAAGTAGGAAAAATTCCCACGGGATTGCCAATGCCTCAA
ATGCCTCCTCTTGAGTTATTAAGTTTGGTAGCCGTTGACTCAATTGCAGTCTGCATTGTT
AGCTATTCGATCGTGATGAGTATGGCATTAATTTTTGCTAAGAAAGAATATTATGAAGTA
AGACCGAATCAAGAATTGTTAGCATTAGGGATTTCGAATATTTTTGGATCATTTTTCTCA
TGCATTCCATTGTCATGCTCTTTATCACGATCAATGATTCAATATTTAGCTGGTGGAAAA
ACACAGCTCACTTCAGTATTTTCTTCTGCAATTATTCTCACAGTTTTGCTTTGGCTTGGT
CCATTATTTGAGACATTACCTCGTGCTACACTTGCTGGAATCATCATTGTGGCTTTAAAA
GGACTTTTAATGCAAGTCAAAGATTTAAAAAGATTTTTAAAAGAAGGAATCCTCGAATCA
GCTGAATGGATCGGAACATTTTTGACAGTTGTTATAATTGACATTGATGTTGGACTACTT
GCTGGTGTGATAATCTCAATTCTTGCACTTTACATTAAAGGATTAAAAAGTTACTCAAGT
ATGCTTGGTCAAGTACCAAACACAAACATTTATGTTCCCATTAAAACTCATAGATTTGTC
AGCCAGCTTCCAAATATCAAAATTTTCCGCTATAGCGGTTCAGTCAATTTTGCAACATCT
TCAGCATTTAAGAAAGCTTTATTCAGTAACATTGGCATTGACTGTCGACTCATCAGACGT
GCATCATTGTGTGAAACTCAATCAGAAGCCAGAGGATTCAATAATGGCATTAGATGTTTG
ATTTTAGACTTGGGATCAATTGCACATATTGACATGAGCGGTTATAGAACATTTTTAGAA
ATACGAAATGAAATGAAATTGATTGATGTTCGAGTTTATCTTGCAAATGCTAGTGATTGC
GTTTATGACTCATTGGTTCGTGCTGTAAATCTTGGATACCCATCATTTGAATTATTTTCA
TCAGTTCACGATGCTGTTTTATTTGCACAAGGTCAAAATGAGCATTAA
>g13335.t1 Gene=g13335 Length=675
MPARIFKNNIIDICETKPRVTIPYTVTRNVFKQEELEQIAGYDRHKDTPSESIRDNLKKL
KPKNLIYELCPVLKWLPEYPIKANLFGDLISGFTVAIMHIPQGMAYGLLAGVDPIVGLYM
AFFPTLIYFLFGTSRHVSMGTFAIVSIMTSKIVSTYADPNYGNTNLNSTNDEPLDQLPYY
HYTPFQVATAVSMVCGFYQIIMCVLRLGILSSLLSEALVNGFTTAAAVHVLVSQLKDILG
LRLPRHQGAFKIILSLRDIILNIPRANVYAIYIAIVCIAFMVVMNEFVKPWVAKRCKFPI
PTELIAVVGFTVISFALNLGGSKYKVREVGKIPTGLPMPQMPPLELLSLVAVDSIAVCIV
SYSIVMSMALIFAKKEYYEVRPNQELLALGISNIFGSFFSCIPLSCSLSRSMIQYLAGGK
TQLTSVFSSAIILTVLLWLGPLFETLPRATLAGIIIVALKGLLMQVKDLKRFLKEGILES
AEWIGTFLTVVIIDIDVGLLAGVIISILALYIKGLKSYSSMLGQVPNTNIYVPIKTHRFV
SQLPNIKIFRYSGSVNFATSSAFKKALFSNIGIDCRLIRRASLCETQSEARGFNNGIRCL
ILDLGSIAHIDMSGYRTFLEIRNEMKLIDVRVYLANASDCVYDSLVRAVNLGYPSFELFS
SVHDAVLFAQGQNEH
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 34 | g13335.t1 | CDD | cd07042 | STAS_SulP_like_sulfate_transporter | 544 | 648 | 5.10924E-15 |
| 8 | g13335.t1 | Gene3D | G3DSA:3.30.750.24 | - | 516 | 673 | 2.3E-31 |
| 4 | g13335.t1 | PANTHER | PTHR11814 | SULFATE TRANSPORTER | 15 | 165 | 3.2E-242 |
| 6 | g13335.t1 | PANTHER | PTHR11814:SF189 | FI18412P1 | 15 | 165 | 3.2E-242 |
| 3 | g13335.t1 | PANTHER | PTHR11814 | SULFATE TRANSPORTER | 184 | 672 | 3.2E-242 |
| 5 | g13335.t1 | PANTHER | PTHR11814:SF189 | FI18412P1 | 184 | 672 | 3.2E-242 |
| 1 | g13335.t1 | Pfam | PF00916 | Sulfate permease family | 85 | 481 | 1.2E-102 |
| 2 | g13335.t1 | Pfam | PF01740 | STAS domain | 542 | 665 | 5.8E-17 |
| 14 | g13335.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 1 | 82 | - |
| 22 | g13335.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 83 | 100 | - |
| 16 | g13335.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 101 | 105 | - |
| 30 | g13335.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 106 | 130 | - |
| 10 | g13335.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 131 | 136 | - |
| 26 | g13335.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 137 | 157 | - |
| 21 | g13335.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 158 | 184 | - |
| 32 | g13335.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 185 | 205 | - |
| 15 | g13335.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 206 | 216 | - |
| 33 | g13335.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 217 | 235 | - |
| 18 | g13335.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 236 | 268 | - |
| 27 | g13335.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 269 | 288 | - |
| 13 | g13335.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 289 | 299 | - |
| 28 | g13335.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 300 | 319 | - |
| 19 | g13335.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 320 | 345 | - |
| 24 | g13335.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 346 | 373 | - |
| 9 | g13335.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 374 | 384 | - |
| 31 | g13335.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 385 | 405 | - |
| 17 | g13335.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 406 | 424 | - |
| 25 | g13335.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 425 | 442 | - |
| 12 | g13335.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 443 | 448 | - |
| 29 | g13335.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 449 | 466 | - |
| 20 | g13335.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 467 | 485 | - |
| 23 | g13335.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 486 | 512 | - |
| 11 | g13335.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 513 | 675 | - |
| 45 | g13335.t1 | ProSiteProfiles | PS50801 | STAS domain profile. | 536 | 669 | 20.918 |
| 7 | g13335.t1 | SUPERFAMILY | SSF52091 | SpoIIaa-like | 540 | 665 | 6.28E-14 |
| 46 | g13335.t1 | TIGRFAM | TIGR00815 | sulP: sulfate permease | 71 | 649 | 1.8E-130 |
| 39 | g13335.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 89 | 111 | - |
| 35 | g13335.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 115 | 132 | - |
| 37 | g13335.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 188 | 210 | - |
| 44 | g13335.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 266 | 288 | - |
| 38 | g13335.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 300 | 322 | - |
| 36 | g13335.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 351 | 373 | - |
| 41 | g13335.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 386 | 408 | - |
| 43 | g13335.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 423 | 442 | - |
| 42 | g13335.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 449 | 466 | - |
| 40 | g13335.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 490 | 512 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016020 | membrane | CC |
| GO:0055085 | transmembrane transport | BP |
| GO:0015116 | sulfate transmembrane transporter activity | MF |
| GO:0008272 | sulfate transport | BP |
| GO:0016021 | integral component of membrane | CC |
| GO:0008271 | secondary active sulfate transmembrane transporter activity | MF |
KEGG
Orthology
- This transcript has been annotated with K14453 (solute carrier family 26, other)
Pathway
This gene does not belong to any pathways.
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
