General information for g13341.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Prestin.
Parent gene
- The parent gene g13341 is located on chr_1: 29377051..29379144 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g13341 | g13341.t1 | isoform | g13341.t1 | 29377051 | 29379144 |
| chr_1 | g13341 | g13341.t1 | exon | g13341.t1.exon1 | 29377051 | 29377195 |
| chr_1 | g13341 | g13341.t1 | cds | g13341.t1.CDS1 | 29377051 | 29377195 |
| chr_1 | g13341 | g13341.t1 | exon | g13341.t1.exon2 | 29377262 | 29379144 |
| chr_1 | g13341 | g13341.t1 | cds | g13341.t1.CDS2 | 29377262 | 29379144 |
| chr_1 | g13341 | g13341.t1 | TTS | g13341.t1 | 29379218 | 29379218 |
| chr_1 | g13341 | g13341.t1 | TSS | g13341.t1 | NA | NA |
Sequences
>g13341.t1 Gene=g13341 Length=2028
ATGTCATGTAAAACATCAAGTAACAGTATTGTTGATATCGAAAAACAAAAGCCTTACAAT
AAAGTGCCTTATCTTGTCGCAAGAAATGTTTTAAAACAAGACGAACTAGAACATGTAGCA
GGATACAATCGACATAAAGACACGCCTCTCGAAACGATACAAGAAAATTTTAAAAAATTT
CAACCAAAAAGTGTCATTTTTGACTTGTTTCCAGCATTGAAATGGATTCCAGAATATCCC
GTTCAGAAAAATCTTGTCAGTGATCTTGTTTCAGGATTTACTGTTGCTATAATGCATATT
CCTCAAGGTATGGGATATGGATTGCTTGCCGGTGTTGATCCAATTGTTGGTCTCTACATG
GCATTCTTTCCTACTTTAATTTATTTTTTATTCGGCACATCGAGACACATAAGCATGGGA
ACTTTTGCTGTCATTTCAATTATGACATCAAAAATTGTTGCGACTTATTCAGATCCTAAT
TATGGAAATACAAACTTAAATTCCACACTTGATGAAGCAGCAGATAATTTGCCTCAATAC
CAATACACTCCATTTCAAGTTGCAACAGCAGTTTCAATGGTTTGTGGCTTCTATCAAATT
ATCATGTGTGTGCTTCGTCTTGGAATACTTTCATCACTTTTATCTGAAGCACTTGTCAAT
GGATTCACAACAGCAGCTGCAGTACATGTTTTTACTTCGCAGTTAAAAGACATCTTAGGC
TTAAAACTCCCTAGACACAAAGGCGCCTTTAAAGTTCTCTTATCACTTCGAGACATTTTT
TCAAATTTACCAAGCGCAAACATGTATGCAATTTATATTTCCATTATTTGCATCTCATTT
ATGTTCTTAATGAACGAATTTGTGAAACCTTGGGTAGCTAAAAAGTGCAAATTTCCTATT
CCAACTGAATTAATGGTGGTCATAAGTTTTACTTTCGTATCATACATGCTCAATCTTGGT
GGATCAGAGTATAAAGTTAGAGAAGTAGGAAAAATTCCCACGGGATTGCCAATGCCTCAA
ATGCCACCAATTGAACTTATTAAGTTGGTAGCTGTTGATTCAATTGCAGTCTGCATTGTT
AGCTATTCCGTCGTCATGAGTATGGCATTAATCTTTGCTAAGAAAGAATATTATGAAGTG
AGACCGAATCAAGAATTGCTCGCATTAGGGCTTTCGAATATTTTTGGATCATTTTTCTCA
TGCATTCCATTATCATGCTCTTTATCACGATCTGTCATTCAATATCAAGCAGGTGGAAAG
ACACAACTCACTTCAGTCTTCTCAGCATCGATAATTCTCACAGTTTTGCTTTGGCTTGGT
CCATTATTTGAGACATTACCTCGTGCTACACTTGCCAGTATTATCATTGTGGCTCTTAAA
GGCATGTTTATGCAAATAAAAGACTTAAAAAGATTTTTAAAAGAAGGAATCCTCGAATCA
GCTGAATGGATCGGAACATTTTTGACAGTTATTATAATTGACATTGATGTTGGACTACTT
GCTGGCGTAATAATCTCAATTCTTGCACTTTACATTAAAGGGTTAAAAAGTTACTCAAGT
ATGCTTGGTCAAGTACCTGATACAGATATTTATGTTAACTTAAATACACACAAAAATGCC
ATACAATTGCCAAATATCAAAATCTTTAGATATAGTGGTTCAATAAATTTTGCAACTTGC
TCAAGTTTTAAGAAAGCACTTTTTGATAATATTGGAGTTAATCATCGACTCATTAGACGT
GCATCATTGTGTGAAACTCAATCAGAAGCTAGAGGATTCAATACTGACATGCATACTTTA
ATAATTGATTTGGGATCAGTGGCACATATTGATATGAGCGGATATAGAACGTTTTTAGAA
ATACGAAGCGAGATGAAACTAATTGATGTCAAAGTATACCTTGCAAATGCCAGTGATTGC
GTTTATGATTCACTTACACGTGCTACAGATCTTGGTCATCCTTCACTCGAATGTTTCTCG
TCTGTACACGATGCTGTTTTATTTGCCTTAAAGAAATTAGAAAATTAG
>g13341.t1 Gene=g13341 Length=675
MSCKTSSNSIVDIEKQKPYNKVPYLVARNVLKQDELEHVAGYNRHKDTPLETIQENFKKF
QPKSVIFDLFPALKWIPEYPVQKNLVSDLVSGFTVAIMHIPQGMGYGLLAGVDPIVGLYM
AFFPTLIYFLFGTSRHISMGTFAVISIMTSKIVATYSDPNYGNTNLNSTLDEAADNLPQY
QYTPFQVATAVSMVCGFYQIIMCVLRLGILSSLLSEALVNGFTTAAAVHVFTSQLKDILG
LKLPRHKGAFKVLLSLRDIFSNLPSANMYAIYISIICISFMFLMNEFVKPWVAKKCKFPI
PTELMVVISFTFVSYMLNLGGSEYKVREVGKIPTGLPMPQMPPIELIKLVAVDSIAVCIV
SYSVVMSMALIFAKKEYYEVRPNQELLALGLSNIFGSFFSCIPLSCSLSRSVIQYQAGGK
TQLTSVFSASIILTVLLWLGPLFETLPRATLASIIIVALKGMFMQIKDLKRFLKEGILES
AEWIGTFLTVIIIDIDVGLLAGVIISILALYIKGLKSYSSMLGQVPDTDIYVNLNTHKNA
IQLPNIKIFRYSGSINFATCSSFKKALFDNIGVNHRLIRRASLCETQSEARGFNTDMHTL
IIDLGSVAHIDMSGYRTFLEIRSEMKLIDVKVYLANASDCVYDSLTRATDLGHPSLECFS
SVHDAVLFALKKLEN
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 30 | g13341.t1 | CDD | cd07042 | STAS_SulP_like_sulfate_transporter | 537 | 663 | 2.79133E-16 |
| 8 | g13341.t1 | Gene3D | G3DSA:3.30.750.24 | - | 518 | 672 | 5.1E-34 |
| 4 | g13341.t1 | PANTHER | PTHR11814 | SULFATE TRANSPORTER | 16 | 165 | 2.4E-238 |
| 6 | g13341.t1 | PANTHER | PTHR11814:SF189 | FI18412P1 | 16 | 165 | 2.4E-238 |
| 3 | g13341.t1 | PANTHER | PTHR11814 | SULFATE TRANSPORTER | 183 | 669 | 2.4E-238 |
| 5 | g13341.t1 | PANTHER | PTHR11814:SF189 | FI18412P1 | 183 | 669 | 2.4E-238 |
| 1 | g13341.t1 | Pfam | PF00916 | Sulfate permease family | 85 | 481 | 9.4E-103 |
| 2 | g13341.t1 | Pfam | PF01740 | STAS domain | 538 | 665 | 1.4E-18 |
| 10 | g13341.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 1 | 105 | - |
| 26 | g13341.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 106 | 131 | - |
| 15 | g13341.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 132 | 184 | - |
| 27 | g13341.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 185 | 205 | - |
| 14 | g13341.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 206 | 216 | - |
| 28 | g13341.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 217 | 235 | - |
| 17 | g13341.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 236 | 268 | - |
| 23 | g13341.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 269 | 288 | - |
| 13 | g13341.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 289 | 299 | - |
| 25 | g13341.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 300 | 317 | - |
| 18 | g13341.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 318 | 345 | - |
| 21 | g13341.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 346 | 373 | - |
| 9 | g13341.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 374 | 384 | - |
| 29 | g13341.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 385 | 405 | - |
| 16 | g13341.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 406 | 424 | - |
| 22 | g13341.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 425 | 442 | - |
| 12 | g13341.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 443 | 448 | - |
| 24 | g13341.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 449 | 466 | - |
| 19 | g13341.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 467 | 485 | - |
| 20 | g13341.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 486 | 512 | - |
| 11 | g13341.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 513 | 675 | - |
| 41 | g13341.t1 | ProSiteProfiles | PS50801 | STAS domain profile. | 536 | 669 | 19.987 |
| 7 | g13341.t1 | SUPERFAMILY | SSF52091 | SpoIIaa-like | 541 | 665 | 2.16E-14 |
| 42 | g13341.t1 | TIGRFAM | TIGR00815 | sulP: sulfate permease | 71 | 664 | 1.9E-135 |
| 35 | g13341.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 89 | 111 | - |
| 31 | g13341.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 115 | 132 | - |
| 33 | g13341.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 188 | 210 | - |
| 40 | g13341.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 266 | 288 | - |
| 34 | g13341.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 300 | 322 | - |
| 32 | g13341.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 351 | 373 | - |
| 37 | g13341.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 386 | 408 | - |
| 39 | g13341.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 423 | 442 | - |
| 38 | g13341.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 449 | 466 | - |
| 36 | g13341.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 490 | 512 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016020 | membrane | CC |
| GO:0055085 | transmembrane transport | BP |
| GO:0015116 | sulfate transmembrane transporter activity | MF |
| GO:0008272 | sulfate transport | BP |
| GO:0016021 | integral component of membrane | CC |
| GO:0008271 | secondary active sulfate transmembrane transporter activity | MF |
KEGG
Orthology
- This transcript has been annotated with K14453 (solute carrier family 26, other)
Pathway
This gene does not belong to any pathways.
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
