General information for g13357.t2
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Myosin heavy chain, non-muscle.
Parent gene
- The parent gene g13357 is located on chr_1: 29507532..29507964 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g13357 | g13357.t2 | isoform | g13357.t2 | 29497951 | 29499332 |
| chr_1 | g13357 | g13357.t2 | exon | g13357.t2.exon1 | 29497951 | 29499332 |
| chr_1 | g13357 | g13357.t2 | cds | g13357.t2.CDS1 | 29497953 | 29499284 |
| chr_1 | g13357 | g13357.t2 | TTS | g13357.t2 | 29497972 | 29497972 |
| chr_1 | g13357 | g13357.t2 | TSS | g13357.t2 | NA | NA |
Sequences
>g13357.t2 Gene=g13357 Length=1382
TGCATTAATTACACAAACGAAAAGCTTCAACAACTTTTTAATCATACAATGTTTATTTTG
GAACAAGAAGAGTATCAACGCGAAGGCATTGATTGGAAATTTATCGATTTTGGTCTCGAT
TTGCAACCAACTATTGATTTGATTGATAAGCCTGGTGGAATTATGGCACTCCTCGATGAA
GAATGTTGGTTCCCGAAAGCAACTGATAAGACTTTTGTAGAAAAATTGACATCAGCCCAC
AGCGCTCACCCGAAATATATGAAAACTGATTTCCGAGGTGTTGCTGATTTTGCAATTGTA
CATTATGCTGGCAGAGTCGATTATTCAGCGGAAAAGTGGCTTATGAAAAATATGGATCCA
TTAAATGAAAACGTTGTTTCATTATTGCAATCATCAGCAGATCCATTTGTTGTTCAAATT
TGGAAAGATGCAGAAATTGTTGGAATGGCTCAACAAGCTCTCAGTGACACACAATTTGGG
GCTCGTACACGTAAAGGAATGTTTAGAACTGTTTCACATTTATATAAGGAACAACTCTCT
AAGCTTATGGATACATTGAAAAATACAAATCCCAATTTTGTTCGTTGCATATTACCAAAT
CATGAAAAGCGTTCTGGTAAAATTGAAGCTCAATTGGTGCTCGATCAACTTCGTTGCAAT
GGAGTTCTCGAAGGGATTCGTATTTGCCGTCAAGGTTTTCCTAATAGAATTCCATTCCAA
GAATTCCGTCAACGCTATGAATTGCTTACTCCAAATGTCATTCCAAAAGGTTTTATGGAC
GGCAAAAAAGCTTGTGAAAAGATGATTCAGGCACTTGAACTTGACAATAATTTATACCGA
GTTGGTCAATCAAAAATTTTCTTCCGTGCTGGTGTTCTAGCTCATCTTGAAGAAGAGCGT
GATTATAAGATAACTGATTTAATTGTCAACTTCCAAGCATTCTGTCGTGGTTATTTAGCT
CGCAGAAATTATCAAAAACGTTTGCAGCAATTGAATGCCATTAGAATCATACAGCGTAAC
TGTGCTGCTTATCTGAAATTGCGTAATTGGCAATGGTGGCGTTTATATACAAAAGTCAAA
CCACTATTGGAAGTCACAAAACAAGAAGAAAAACTTGTGCAAAAGGAAGATGAATTGCGT
CAAATTCGTGAGAAGCTTGATACACTCTCAAAAGCAACAGCTGAGTATGAAAACAAATAT
CAAATGGCCATCGAAGAAAAGACTCATCTGGCTGAACAATTGCAAGCCGAGATTGAATTA
TGTGCTGAAGCAGAAGAAAGTAGAATGCGATTGGCTTCACGCAAACAAGAACTTGAAGAG
ATGATGCAAGATTTAGAGGCGCGTGTCGAAGAAGAAGAAGAAAGGGTCAATGCACTTAAC
AA
>g13357.t2 Gene=g13357 Length=444
MFILEQEEYQREGIDWKFIDFGLDLQPTIDLIDKPGGIMALLDEECWFPKATDKTFVEKL
TSAHSAHPKYMKTDFRGVADFAIVHYAGRVDYSAEKWLMKNMDPLNENVVSLLQSSADPF
VVQIWKDAEIVGMAQQALSDTQFGARTRKGMFRTVSHLYKEQLSKLMDTLKNTNPNFVRC
ILPNHEKRSGKIEAQLVLDQLRCNGVLEGIRICRQGFPNRIPFQEFRQRYELLTPNVIPK
GFMDGKKACEKMIQALELDNNLYRVGQSKIFFRAGVLAHLEEERDYKITDLIVNFQAFCR
GYLARRNYQKRLQQLNAIRIIQRNCAAYLKLRNWQWWRLYTKVKPLLEVTKQEEKLVQKE
DELRQIREKLDTLSKATAEYENKYQMAIEEKTHLAEQLQAEIELCAEAEESRMRLASRKQ
ELEEMMQDLEARVEEEEERVNALN
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 14 | g13357.t2 | Coils | Coil | Coil | 349 | 444 | - |
| 13 | g13357.t2 | Gene3D | G3DSA:1.20.58.530 | - | 1 | 173 | 3.6E-56 |
| 10 | g13357.t2 | Gene3D | G3DSA:3.30.70.3240 | - | 216 | 285 | 1.1E-27 |
| 12 | g13357.t2 | Gene3D | G3DSA:4.10.270.10 | Myosin | 286 | 344 | 2.5E-29 |
| 11 | g13357.t2 | Gene3D | G3DSA:1.20.5.1050 | - | 345 | 444 | 5.3E-13 |
| 4 | g13357.t2 | PANTHER | PTHR45615:SF16 | MYOSIN-9 | 1 | 443 | 1.9E-229 |
| 5 | g13357.t2 | PANTHER | PTHR45615 | MYOSIN HEAVY CHAIN, NON-MUSCLE | 1 | 443 | 1.9E-229 |
| 1 | g13357.t2 | Pfam | PF00063 | Myosin head (motor domain) | 1 | 273 | 1.2E-111 |
| 3 | g13357.t2 | Pfam | PF00612 | IQ calmodulin-binding motif | 291 | 309 | 1.5E-5 |
| 2 | g13357.t2 | Pfam | PF01576 | Myosin tail | 350 | 443 | 1.4E-24 |
| 15 | g13357.t2 | ProSiteProfiles | PS51456 | Myosin motor domain profile. | 1 | 285 | 102.233 |
| 16 | g13357.t2 | ProSiteProfiles | PS50096 | IQ motif profile. | 288 | 317 | 10.621 |
| 9 | g13357.t2 | SMART | SM00242 | MYSc_2a | 1 | 286 | 2.2E-27 |
| 8 | g13357.t2 | SMART | SM00015 | iq_5 | 287 | 309 | 2.0E-4 |
| 7 | g13357.t2 | SUPERFAMILY | SSF52540 | P-loop containing nucleoside triphosphate hydrolases | 1 | 347 | 1.86E-109 |
| 6 | g13357.t2 | SUPERFAMILY | SSF90257 | Myosin rod fragments | 345 | 443 | 3.79E-15 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005524 | ATP binding | MF |
| GO:0005515 | protein binding | MF |
| GO:0016459 | myosin complex | CC |
| GO:0003774 | cytoskeletal motor activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed