General information for g13443.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Protein phosphatase Slingshot.
Parent gene
- The parent gene g13443 is located on chr_1: 30187180..30187710 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g13443 | g13443.t1 | isoform | g13443.t1 | 30170266 | 30187710 |
| chr_1 | g13443 | g13443.t1 | exon | g13443.t1.exon1 | 30170266 | 30170517 |
| chr_1 | g13443 | g13443.t1 | cds | g13443.t1.CDS1 | 30170266 | 30170517 |
| chr_1 | g13443 | g13443.t1 | exon | g13443.t1.exon2 | 30172406 | 30172455 |
| chr_1 | g13443 | g13443.t1 | cds | g13443.t1.CDS2 | 30172406 | 30172455 |
| chr_1 | g13443 | g13443.t1 | exon | g13443.t1.exon3 | 30178241 | 30178448 |
| chr_1 | g13443 | g13443.t1 | cds | g13443.t1.CDS3 | 30178241 | 30178448 |
| chr_1 | g13443 | g13443.t1 | exon | g13443.t1.exon4 | 30179252 | 30179871 |
| chr_1 | g13443 | g13443.t1 | cds | g13443.t1.CDS4 | 30179252 | 30179871 |
| chr_1 | g13443 | g13443.t1 | exon | g13443.t1.exon5 | 30180210 | 30180275 |
| chr_1 | g13443 | g13443.t1 | cds | g13443.t1.CDS5 | 30180210 | 30180275 |
| chr_1 | g13443 | g13443.t1 | exon | g13443.t1.exon6 | 30184622 | 30184816 |
| chr_1 | g13443 | g13443.t1 | cds | g13443.t1.CDS6 | 30184622 | 30184816 |
| chr_1 | g13443 | g13443.t1 | exon | g13443.t1.exon7 | 30184900 | 30185169 |
| chr_1 | g13443 | g13443.t1 | cds | g13443.t1.CDS7 | 30184900 | 30185169 |
| chr_1 | g13443 | g13443.t1 | exon | g13443.t1.exon8 | 30185229 | 30187710 |
| chr_1 | g13443 | g13443.t1 | cds | g13443.t1.CDS8 | 30185229 | 30187710 |
| chr_1 | g13443 | g13443.t1 | TTS | g13443.t1 | 30188100 | 30188100 |
| chr_1 | g13443 | g13443.t1 | TSS | g13443.t1 | NA | NA |
Sequences
>g13443.t1 Gene=g13443 Length=4143
ATGTTGTACATTTTACCGCCTCCAAGTAATCCATCTCCTACTGTTTGGGATTTAATATTA
AATTTTCATCAAAAAGGATGTCAAGAGAACGATACAAGTTGTGGTTCAAATATGGAATCG
CCTTCAGCACGTTCTTCATCATCACATAAATCAAATTCAATAAAATTTGATAAAGGACAA
AACTGTCATAGAAAATCAAAACGCAACAGCTGGTACAAAACATCGTCGCAATCGTCCACA
AATCAATCTCACGATTCTGGCGGTGTATTACGTGAAGAAGAAAATCAGAGAGCATGTAAA
AGTTTAAATGAATGTTATTTCGCTGGCAAAGGTACAGCATTAATGCTAGGTTCAAATGAG
CGCCTACAGCGTCAGGTAGATGGACGACGATTAAGTCAAATATCAAATGAACTCTCTGCA
AGTCAAACGTCAATCGGTAGCAGTATTGATATACAACAACATTTACAATCTATGTTCTAT
TTATTGAGACCCGAAGAAACACTAAAAATGGCTGTAAAGTTGGAATCATTGCGCGCTGGT
CGCACCCGTTATTTAGTGGTAGTTTCACGTCCTGCCTCAAAAAAAGCACAACAATTAACA
GCATGTGCAAGTTCAAACCGTAACAATAATCAACTGCCATTAATGACAACAACATCAACA
ACGACTGAAACTATTACATCACATTTTAATAGTAACATAATTAATAGTTGTAGCGCTGCT
GATGATGAAAATATTAATCAAAGAAGAAATAGTCATGAAGATATTGATTGTAACAATCGA
TTTAGTACAGCATCATCTACAACGATGACAACAGTAACAACTAGTTATCAGCAAATGAAC
AATTTAAGTTCTAATGTGACATCAGCCGTGACATGTGATAATGAATGTTTAACAATGTAT
AATAATCTTGCACAAACTTGCGCCGTTGCCTCAACCTCCTCGTTCTGCAATGCAGATGAC
ATTCAACAATGTGATAATGAATCGACAGTTGGAAGTAGTTGCAGCAGTAAAAGCTCCTCA
AATGAAATCGAGGAATCATGTTTATTAGGAATCGACTGTAATGAGAAGACAACAGTTGGC
TTAGTGCTTAAAGTACTTGCAGATACCGCTATAAGACTAGATGGTGACGGTGGCTTCAGC
GTAAGTGTTTGCGGTCGTCAGCATATCTTTAAGCCAGTTTCTGTTCAAGCCATGTGGTCG
GCTCTTCAAACACTTTACAAAATCTCATCGAAAGCACAAGAGCACAATTTTTTCTCTGGT
GGACAGTCGCATGAATGGGTTCAATATTATGAGAATCGTATAGAATCAGATAGATCGTGT
CTAAATGAATGGCATGCAATGGATTCTATTGAAAGTCGAAGACCTCCTTCGCCAGATACT
ATAAGAAATAAGCCCACTGAACGTGATGAAACTGAGAGAGTTATTCGAACAGCTTTAAAG
GAAATAATGATGTCAGTAGATCTTGATGAAGTTACATCGAAATACATACGAGGGCGACTA
GAAGAACATTTAGATATGGACTTAGGTGAATTCAAGTCATTTATCGATGAAGAGATGCTT
GTGATTTTAGGACAAATGGATGCACCAACAGAAATTTTTGATCATGTATATTTAGGATCA
GAATGGAATGCCAGTAATTTAGAAGAACTTCAAAGAAATGGTGTTGGACACATTTTAAAT
GTCACAAGAGAAATTGACAATTTCTTTCCTGGAATGTTTGATTATTTCAACGTGAGAGTT
TATGATGATGAAAAAACAGATTTACTTAAACATTGGGATAATACATTTAAATATATTTCT
CGTGCCAGACGAGAAGGCTCAAAAGTGCTTGTACATTGTAAAATGGGTATAAGTCGATCG
GCATCAGTAGTTATCGCATATGCAATGAAAGCATACAATTGGGATTTCTGTAAAGCCATT
CAACATGTTAAGGATAAGAGAAGCTGCATAAAACCAAACAAAAACTTTTTAGCACAATTG
GAAACGTATCAGGGTATTCTGGACGCAATGAAGAATAAAGAAAAATTACAACGTAGTAAA
AGTGAAACAAATTTAAAGTCAGAAAATTCAAAAGATGGAAAAAGTTTGCCTGGGAGTGAA
CCAACACCATTGATTCAAGCGCTACAGCACAATAAAAATTCAACATATCCATCGAGTAAA
AAAGAAGCATCTTATTTAAAGCGAATAAATCAGAGACCAAATAGCTCCCCAGACATTTCA
AAATCAGCCAGTGAAACGCTCTCAATAAAACCACTTTCAATCTCTCTGGAGACTCTCGTG
ACAATTGACACTCAGGATCCTCAAGCTACAAATGTGTCGGAAACTACAAATTTACGATGG
CCATGTAAAAATGGTCACTATTCAATATCACAAAACCAAATAATCTACTTGGAAAATGAA
TCAGCCAACAATTCCTTAATTGCTGGAAATTCGAATATAGATAGTGCTGAAACAATAACC
ACAACAAGTGTGCCATTAGTTCGAAGCATCATAACTGAACTTGAGCAGCATCATGAAAAG
ATGAAAAGAAAAGAAGAAGATAATCAAGAGCGAGAAGTTTCACAAAAGAAAGAGCCAGAT
ATTGAGGAGACATCAAAGCAAGTTTATACATGTTCAGCAGAGATAATTCATCAAGATAAA
GTGGCTTCTTTAATTCAACCCCTCTCGGCCATTAAACGATCTCCTAGTGCTAAAAGAGAA
GGAGACAGTTTTAGTAAACAAGTTGATCGAGTATTTGATCGTGAAGAAAAGCGTCAGAGT
TCAAATTTCATTTCACGTCAGAGTAGTTGGAGTAGTGTTGATTCGGCATGTGTAATTGGC
GATTTGCCATCAAGAAATTCATCTATGGGTTCTGCAGATTCAAGGCCATCAAGAAATTCA
TCATGGGGCTCTTATGATACAGCAAAGCCAGTTCAATCAGTCAGTGAAGATGTAGTTATG
GGACAAAGTGGAATTTTTCCTTATGAAAAAAATGAAATTCCCTGGCATCCAGGTACAGTG
AAACGAACAAAACAAAAAATTGAAGAGAAACAAACATTACCCATAATGCGATCATCTTCT
GGTCCAGCGTCAAATCAACAAATTGATGCCAAAAACAATAAAATTCTATGTGATATTAAA
AATATTAAAACGTCTTTACTAATTGACAATTTATCTAATCGCACCACAAATACGAGCAAC
AGAGGACCATCATTATCATCATCACCACAACAGCCGCATAAATTTGCCAAATTACAACAA
TCGTCGTCTGTATCGTCAGCTGCAATAAGCAGTAGTAAAACGCATACACGATGCAGAAGT
GAAGAATATTTATCAGCACAACGCGCTAGAAATAATGATCGAAATAATAATCAACCATTG
TCGGTATCAGCACCCGATACATTTTGTATGAACTTGATTAAAAACAACAAAGATATTGCA
GTTTCATCTGCTACACTTAAACTTCAACAGAGACGAATACAAAAATCACTCACTGTAGAA
AGTGATGTTGATGGAAGTGGTGAACGAAGAAATAGATCGCGAGATAGTCAGCAACAAGTT
GGTAAGGTTAAGAATTTAAAAATGAATTTCGAAGCAAAAGCAAACAATACTAATAGTAAT
AGCGGAAATAATGCAACTGTAATTCGTGAGAATAAGAAAAATAGTCACTCACTTCCGTCT
TCACCAATTGCAATTCATATTGACGTAACTTCTGCTGCCAGTGGCGGATTTCCGAGCTCA
AATTCTTCTGATGTGAGTTCAGAGGACATAAATGTACGTGGACTGGTTGATCGCTATGAA
ATTGGTAAAGTAAAGACTTTAATGTCACCAAATACACGACAACGGCCAAGATCACTTTAT
GAATCAAAATTTCAATTAAAAGCTTTTCAAAATAAGCAACCACTATTGATCTCACATCAA
ACTATTTTCACAAAGGGTGATGAATTTAAACAACAACGTCCACCAATTCCTTTGCAGCAG
CAGCAACCAATTGTGAAAAATACATTGATGACAAGCAATCAAAATTTTGTTTGCAGCACA
AAACAGACGGTTGGCAATTGTCGAAAAATGCAACAAGGAAAGACTCATCCCTTATCTAAA
CTTGGAATAAATAATAAACAAAGAATCAATACAAGTCCAGCGACTGCCTATAATACGATG
TAA
>g13443.t1 Gene=g13443 Length=1380
MLYILPPPSNPSPTVWDLILNFHQKGCQENDTSCGSNMESPSARSSSSHKSNSIKFDKGQ
NCHRKSKRNSWYKTSSQSSTNQSHDSGGVLREEENQRACKSLNECYFAGKGTALMLGSNE
RLQRQVDGRRLSQISNELSASQTSIGSSIDIQQHLQSMFYLLRPEETLKMAVKLESLRAG
RTRYLVVVSRPASKKAQQLTACASSNRNNNQLPLMTTTSTTTETITSHFNSNIINSCSAA
DDENINQRRNSHEDIDCNNRFSTASSTTMTTVTTSYQQMNNLSSNVTSAVTCDNECLTMY
NNLAQTCAVASTSSFCNADDIQQCDNESTVGSSCSSKSSSNEIEESCLLGIDCNEKTTVG
LVLKVLADTAIRLDGDGGFSVSVCGRQHIFKPVSVQAMWSALQTLYKISSKAQEHNFFSG
GQSHEWVQYYENRIESDRSCLNEWHAMDSIESRRPPSPDTIRNKPTERDETERVIRTALK
EIMMSVDLDEVTSKYIRGRLEEHLDMDLGEFKSFIDEEMLVILGQMDAPTEIFDHVYLGS
EWNASNLEELQRNGVGHILNVTREIDNFFPGMFDYFNVRVYDDEKTDLLKHWDNTFKYIS
RARREGSKVLVHCKMGISRSASVVIAYAMKAYNWDFCKAIQHVKDKRSCIKPNKNFLAQL
ETYQGILDAMKNKEKLQRSKSETNLKSENSKDGKSLPGSEPTPLIQALQHNKNSTYPSSK
KEASYLKRINQRPNSSPDISKSASETLSIKPLSISLETLVTIDTQDPQATNVSETTNLRW
PCKNGHYSISQNQIIYLENESANNSLIAGNSNIDSAETITTTSVPLVRSIITELEQHHEK
MKRKEEDNQEREVSQKKEPDIEETSKQVYTCSAEIIHQDKVASLIQPLSAIKRSPSAKRE
GDSFSKQVDRVFDREEKRQSSNFISRQSSWSSVDSACVIGDLPSRNSSMGSADSRPSRNS
SWGSYDTAKPVQSVSEDVVMGQSGIFPYEKNEIPWHPGTVKRTKQKIEEKQTLPIMRSSS
GPASNQQIDAKNNKILCDIKNIKTSLLIDNLSNRTTNTSNRGPSLSSSPQQPHKFAKLQQ
SSSVSSAAISSSKTHTRCRSEEYLSAQRARNNDRNNNQPLSVSAPDTFCMNLIKNNKDIA
VSSATLKLQQRRIQKSLTVESDVDGSGERRNRSRDSQQQVGKVKNLKMNFEAKANNTNSN
SGNNATVIRENKKNSHSLPSSPIAIHIDVTSAASGGFPSSNSSDVSSEDINVRGLVDRYE
IGKVKTLMSPNTRQRPRSLYESKFQLKAFQNKQPLLISHQTIFTKGDEFKQQRPPIPLQQ
QQPIVKNTLMTSNQNFVCSTKQTVGNCRKMQQGKTHPLSKLGINNKQRINTSPATAYNTM
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 8 | g13443.t1 | Coils | Coil | Coil | 827 | 851 | - |
| 7 | g13443.t1 | Gene3D | G3DSA:3.90.190.10 | Protein tyrosine phosphatase superfamily | 523 | 680 | 6.8E-53 |
| 13 | g13443.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 31 | 92 | - |
| 23 | g13443.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 31 | 55 | - |
| 21 | g13443.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 71 | 86 | - |
| 18 | g13443.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 449 | 470 | - |
| 12 | g13443.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 675 | 689 | - |
| 15 | g13443.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 675 | 699 | - |
| 19 | g13443.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 837 | 864 | - |
| 22 | g13443.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 837 | 865 | - |
| 20 | g13443.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 944 | 974 | - |
| 11 | g13443.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1053 | 1094 | - |
| 16 | g13443.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1053 | 1100 | - |
| 14 | g13443.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1158 | 1185 | - |
| 17 | g13443.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1162 | 1177 | - |
| 3 | g13443.t1 | PANTHER | PTHR45864:SF2 | PROTEIN PHOSPHATASE SLINGSHOT | 75 | 1380 | 3.6E-283 |
| 4 | g13443.t1 | PANTHER | PTHR45864 | SLINGSHOT PROTEIN PHOSPHATASE HOMOLOG | 75 | 1380 | 3.6E-283 |
| 1 | g13443.t1 | Pfam | PF08766 | DEK C terminal domain | 470 | 523 | 1.3E-14 |
| 2 | g13443.t1 | Pfam | PF00782 | Dual specificity phosphatase, catalytic domain | 536 | 664 | 4.3E-33 |
| 9 | g13443.t1 | ProSitePatterns | PS00383 | Tyrosine specific protein phosphatases active site. | 611 | 621 | - |
| 24 | g13443.t1 | ProSiteProfiles | PS50054 | Dual specificity protein phosphatase family profile. | 528 | 668 | 38.0 |
| 25 | g13443.t1 | ProSiteProfiles | PS50056 | Tyrosine specific protein phosphatases family profile. | 590 | 647 | 13.075 |
| 10 | g13443.t1 | SMART | SM00195 | dsp_5 | 528 | 666 | 1.6E-43 |
| 5 | g13443.t1 | SUPERFAMILY | SSF109715 | DEK C-terminal domain | 469 | 519 | 6.54E-6 |
| 6 | g13443.t1 | SUPERFAMILY | SSF52799 | (Phosphotyrosine protein) phosphatases II | 519 | 669 | 1.25E-41 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0003779 | actin binding | MF |
| GO:0030837 | negative regulation of actin filament polymerization | BP |
| GO:0008138 | protein tyrosine/serine/threonine phosphatase activity | MF |
| GO:0006470 | protein dephosphorylation | BP |
| GO:0016311 | dephosphorylation | BP |
| GO:0004725 | protein tyrosine phosphatase activity | MF |
| GO:0016791 | phosphatase activity | MF |
KEGG
Orthology
- This transcript has been annotated with K05766 (protein phosphatase slingshot)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
