General information for g13490.t184
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Extracellular superoxide dismutase [Cu-Zn].
Parent gene
- The parent gene g13490 is located on chr_1: 30457945..30461971 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g13490 | g13490.t184 | TTS | g13490.t184 | 30456939 | 30456939 |
| chr_1 | g13490 | g13490.t184 | isoform | g13490.t184 | 30457118 | 30461913 |
| chr_1 | g13490 | g13490.t184 | exon | g13490.t184.exon1 | 30457118 | 30457803 |
| chr_1 | g13490 | g13490.t184 | cds | g13490.t184.CDS1 | 30457518 | 30457803 |
| chr_1 | g13490 | g13490.t184 | exon | g13490.t184.exon2 | 30457858 | 30457881 |
| chr_1 | g13490 | g13490.t184 | cds | g13490.t184.CDS2 | 30457858 | 30457881 |
| chr_1 | g13490 | g13490.t184 | exon | g13490.t184.exon3 | 30457941 | 30458040 |
| chr_1 | g13490 | g13490.t184 | cds | g13490.t184.CDS3 | 30457941 | 30458040 |
| chr_1 | g13490 | g13490.t184 | exon | g13490.t184.exon4 | 30458178 | 30458342 |
| chr_1 | g13490 | g13490.t184 | cds | g13490.t184.CDS4 | 30458178 | 30458295 |
| chr_1 | g13490 | g13490.t184 | exon | g13490.t184.exon5 | 30461773 | 30461913 |
| chr_1 | g13490 | g13490.t184 | TSS | g13490.t184 | NA | NA |
Sequences
>g13490.t184 Gene=g13490 Length=1116
TGTAAGAGAGAAAAAAAAATAATTTTTTACATTGTCTGTCTGTTTTAATTTGAAGAAAGA
TTCATTCTATTGTAAAACGTGCATCGCTCGACATTTTGTAGATTTTAATGCTTTTCTTCT
ACTATAATCAAGCTAAAGTAGATCAGTTGCAATCATTTCATTCAACATCAAAGACCTAAA
AATACGAGATGAAATCCTTAGTCATCATTTTCGTAATTTGTCTCTCAACAATCATCGTCA
ATGGCGATGAAGCGAAGCCTGCAAAAGCTATAGCAGTGCTTGGATTCTCAAACTCCGTCC
ATGGAAACATCACTTTCTCACAATCATCCTGTACGGAAGCAGTTCTCGTTCAAATTGAAA
TAACTGGCCTTACACCAGGCAAACACGGCTTTCATGTTCACGAAAAAGGCGATTTGTCGA
ATGGATGCACGAGCACAGGAAGTCATTTCAACCCAGATCGCTTGAATCATGGCGCACGTG
AAGCACAAGTTCGTCACGTTGGTGATTTGGGCAACGTTGTTGCTGATGATCAAGGACGCG
TCTCAACATCATTTTCGGATAATGTCATTACATTGTTTGGTGCTCGAAGTATCATTGGTA
GAGCAATTGTTGTTCACACCGATGAAGATGACCTTGGTCTTACCGATCATCAAGACTCTC
ATAAAACGGGAAATGCTGGTGGACGTGTTGCATGCGGAATTATTGGAATCTTGTAAATAT
TTTTTTCTCTTTTCTCACTTTTCTTATCATCATTTTTGCTTTTTATACATACACAAGAAT
AAGAAGAGAATTTCTGTTTAGTGAGAATAAAAATAATTCTTAATCGTCATGTGTTCATTT
GACCCTGTAAAAATGTTATTAACTGTTGATGTGTGCGTGAGTAAAATGTATCAAGGTGAA
GGTCATTTGCTCACACAATTGATAGCTAAATGTGCATTTATCACTTGACTTTTTTGATCG
AATGAATTTCAATCATTTACAGGGAGCCATCGAATGACGAATGGACATGTAATTCATCAT
CGAGAACACAAGTGGGATTATTGTTGATTCTCGTTATTATTGCTGTAATTAGAGCATAAA
CTCTTCTCTTTTATTTATTTGTAGCATACTCGCTAA
>g13490.t184 Gene=g13490 Length=175
MKSLVIIFVICLSTIIVNGDEAKPAKAIAVLGFSNSVHGNITFSQSSCTEAVLVQIEITG
LTPGKHGFHVHEKGDLSNGCTSTGSHFNPDRLNHGAREAQVRHVGDLGNVVADDQGRVST
SFSDNVITLFGARSIIGRAIVVHTDEDDLGLTDHQDSHKTGNAGGRVACGIIGIL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 17 | g13490.t184 | CDD | cd00305 | Cu-Zn_Superoxide_Dismutase | 26 | 169 | 4.93097E-57 |
| 11 | g13490.t184 | Gene3D | G3DSA:2.60.40.200 | - | 16 | 174 | 3.6E-58 |
| 2 | g13490.t184 | PANTHER | PTHR10003 | SUPEROXIDE DISMUTASE CU-ZN -RELATED | 12 | 174 | 2.5E-53 |
| 3 | g13490.t184 | PANTHER | PTHR10003:SF31 | SUPEROXIDE DISMUTASE [CU-ZN] 3 | 12 | 174 | 2.5E-53 |
| 5 | g13490.t184 | PRINTS | PR00068 | Cu-Zn-superoxide dismutase family signature | 67 | 89 | 6.6E-40 |
| 7 | g13490.t184 | PRINTS | PR00068 | Cu-Zn-superoxide dismutase family signature | 103 | 112 | 6.6E-40 |
| 6 | g13490.t184 | PRINTS | PR00068 | Cu-Zn-superoxide dismutase family signature | 122 | 144 | 6.6E-40 |
| 4 | g13490.t184 | PRINTS | PR00068 | Cu-Zn-superoxide dismutase family signature | 147 | 173 | 6.6E-40 |
| 1 | g13490.t184 | Pfam | PF00080 | Copper/zinc superoxide dismutase (SODC) | 34 | 172 | 1.1E-46 |
| 13 | g13490.t184 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 19 | - |
| 14 | g13490.t184 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 3 | - |
| 15 | g13490.t184 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 4 | 15 | - |
| 16 | g13490.t184 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 16 | 19 | - |
| 12 | g13490.t184 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 20 | 175 | - |
| 19 | g13490.t184 | ProSitePatterns | PS00087 | Copper/Zinc superoxide dismutase signature 1. | 67 | 77 | - |
| 18 | g13490.t184 | ProSitePatterns | PS00332 | Copper/Zinc superoxide dismutase signature 2. | 161 | 172 | - |
| 8 | g13490.t184 | SUPERFAMILY | SSF49329 | Cu,Zn superoxide dismutase-like | 26 | 174 | 3.53E-54 |
| 10 | g13490.t184 | SignalP_EUK | SignalP-noTM | SignalP-noTM | 1 | 19 | - |
| 9 | g13490.t184 | SignalP_GRAM_POSITIVE | SignalP-TM | SignalP-TM | 1 | 22 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0006801 | superoxide metabolic process | BP |
| GO:0004784 | superoxide dismutase activity | MF |
| GO:0046872 | metal ion binding | MF |
| GO:0055114 | NA | NA |
KEGG
Orthology
- This transcript has been annotated with K04565 (superoxide dismutase, Cu-Zn family)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed