General information for g13576.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Cyclin-dependent kinase 5 activator 1.
Parent gene
- The parent gene g13576 is located on chr_1: 31014228..31020183 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g13576 | g13576.t1 | isoform | g13576.t1 | 31014228 | 31020183 |
| chr_1 | g13576 | g13576.t1 | exon | g13576.t1.exon1 | 31014228 | 31014245 |
| chr_1 | g13576 | g13576.t1 | cds | g13576.t1.CDS1 | 31014228 | 31014245 |
| chr_1 | g13576 | g13576.t1 | exon | g13576.t1.exon2 | 31014934 | 31015071 |
| chr_1 | g13576 | g13576.t1 | cds | g13576.t1.CDS2 | 31014934 | 31015071 |
| chr_1 | g13576 | g13576.t1 | exon | g13576.t1.exon3 | 31019509 | 31019714 |
| chr_1 | g13576 | g13576.t1 | cds | g13576.t1.CDS3 | 31019509 | 31019714 |
| chr_1 | g13576 | g13576.t1 | exon | g13576.t1.exon4 | 31019778 | 31020183 |
| chr_1 | g13576 | g13576.t1 | cds | g13576.t1.CDS4 | 31019778 | 31020183 |
| chr_1 | g13576 | g13576.t1 | TTS | g13576.t1 | 31021184 | 31021184 |
| chr_1 | g13576 | g13576.t1 | TSS | g13576.t1 | NA | NA |
Sequences
>g13576.t1 Gene=g13576 Length=768
ATGAAATTTTCAATAAAAGCCTCAACATCTGAGTTGTTAAAATGCCTTGGAATATTTTTA
CGAGATCGCTGCTGCAAACTGCGTGACTTTCAAGCAGGCGATGCCGTCATGTGGCTTCGA
GCTGTTGATCGCAGTTTGTTACTTCAAGGCTGGCAGGACGTAGCATTTATTAATCCAGCT
AATGTTGTCTTTGTTTACATGTTGGTGCGAGAAATGGTCGATGGTCGGGAGACAGAAGAG
TTAGATCTGCAAGCAAAAGTGCTGACATGCTTATATTTATCATATTCATACATGGGAAAT
GAAATTAGTTATCCTTTAAAGCCCTTCTTGGTTGAAGAATCCAAAGATAAATTTTGGGAT
CGTTGTCTTCTTATCGTCAATAAAATGAGCACGAATATGCTTCGTATTAATGCTGAGCCT
GGATATTTTACTGAAATATTTACAGAACTAAAAGCTCGCGGTATAAGCTCGCCAATAGAG
AATCAATTAAATAATAATCATCTCATTAGTCCAAGCTCACACATTACTAACAATTTGTTG
TCGAGCACGATGAACAATTTAAATATAAATGGTAATAGCAGTGGCGGTGGTAACAATAAT
ATTAGTAACAATAATAACAACATAATAACGAGTAGTGTCAATAACAAGAGTTCAACGAAC
GTCAATATTGTCTCACCAACGACAGCTATGAATAACTTAAACAGCATAAACAATAATAAT
CATTTGAGTCAATCAAATGGAAATCTCCAACAATACGGTTCTGCTTGA
>g13576.t1 Gene=g13576 Length=255
MKFSIKASTSELLKCLGIFLRDRCCKLRDFQAGDAVMWLRAVDRSLLLQGWQDVAFINPA
NVVFVYMLVREMVDGRETEELDLQAKVLTCLYLSYSYMGNEISYPLKPFLVEESKDKFWD
RCLLIVNKMSTNMLRINAEPGYFTEIFTELKARGISSPIENQLNNNHLISPSSHITNNLL
SSTMNNLNINGNSSGGGNNNISNNNNNIITSSVNNKSSTNVNIVSPTTAMNNLNSINNNN
HLSQSNGNLQQYGSA
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 4 | g13576.t1 | Gene3D | G3DSA:1.10.472.10 | - | 6 | 154 | 0 |
| 2 | g13576.t1 | PANTHER | PTHR23401 | CYCLIN DEPENDANT KINASE-5 ACTIVATOR | 3 | 178 | 0 |
| 1 | g13576.t1 | Pfam | PF03261 | Cyclin-dependent kinase 5 activator protein | 4 | 154 | 0 |
| 3 | g13576.t1 | SUPERFAMILY | SSF47954 | Cyclin-like | 8 | 152 | 0 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016533 | protein kinase 5 complex | CC |
| GO:0061575 | cyclin-dependent protein serine/threonine kinase activator activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed