General information for g13580.t23
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Cytochrome P450 9e2.
Parent gene
- The parent gene g13580 is located on chr_1: 31042311..31047040 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g13580 | g13580.t23 | TSS | g13580.t23 | 31040681 | 31040681 |
| chr_1 | g13580 | g13580.t23 | isoform | g13580.t23 | 31041613 | 31042702 |
| chr_1 | g13580 | g13580.t23 | exon | g13580.t23.exon1 | 31041613 | 31041781 |
| chr_1 | g13580 | g13580.t23 | cds | g13580.t23.CDS1 | 31041623 | 31041781 |
| chr_1 | g13580 | g13580.t23 | exon | g13580.t23.exon2 | 31041837 | 31042235 |
| chr_1 | g13580 | g13580.t23 | cds | g13580.t23.CDS2 | 31041837 | 31042235 |
| chr_1 | g13580 | g13580.t23 | exon | g13580.t23.exon3 | 31042300 | 31042702 |
| chr_1 | g13580 | g13580.t23 | cds | g13580.t23.CDS3 | 31042300 | 31042701 |
| chr_1 | g13580 | g13580.t23 | TTS | g13580.t23 | 31043048 | 31043048 |
Sequences
>g13580.t23 Gene=g13580 Length=971
AGGCTCGAAGATGCGCTTAATGTTCAAATTGATGAATGAAGTGGGATCGAAAATGTCGAA
GACTGTTTGTGATAAAATCAATAAAGGCGCAGACAATAAAGTTGAATTTAAAGAGTTCTC
GAGAAAATTCACGATTGATATAATAGCAACTTGTGCATTTGGCATTGAAGTTAATTCATT
TGAAAATGCAAATAATGACTTCATGAGAATTGCAACAAAAGCTACAAACTTTAATTCTTC
AGGAATGCTTCTTAAATTGATTGGATTTTTTGGATTTCCATGGTTGATGAGTCGATTAAG
AGTAAAATTTTTAGATAGTGAACTTTACGACTTTTTCGATAATGTCATTACTGAAACAAT
TAACACAAGAGAACGAAAAGAAATTACTCGAAATGACATGATTGATTTACTTTTGCAAGC
AAAACATGGAAAGCTTGAATATCAAGAAGAAAAATCATCATCTGATGGATTTGCTACTGT
TGAAGAATCACAAATTGGAAAACAAAAAGTCAAAACTGTCTGGAGCAACCAAGACTTGAT
GGCTCAATGTTTTATCTTCTTCTTTGCTGGTTTCGAAACAGTTTCAAATGTGATGACCTT
TATGGCATATGAACTCATTCTCAATCCTGATATTCAAAAGAAATTGCAAGATGAAATTGA
TGCAATGAATGCTGAACTCAAAGGAGGTGATTTGACTTATGAAGATGTTCAGAAACTAAA
ATATATGGATATGGTACTTTGTGAAACTTTGAGAATGTGGCCACCAGCTCCTATCATTGA
TAGAATGTGTACAAAAGATTTTCTCTTGGAATATGACAACAAAAAAGTTCAAATTGAAGT
TGGCAGAAATTTCTATATTCCTGTCTATTCTTTGCATCATAACGAAAACTACTTTCCAAA
TCCGAATAGATTTGATCCAGAACGTTTCAGTGATGAAAACAAGAAAAACATCAGACAGGA
TTGTTATTTAC
>g13580.t23 Gene=g13580 Length=320
MRLMFKLMNEVGSKMSKTVCDKINKGADNKVEFKEFSRKFTIDIIATCAFGIEVNSFENA
NNDFMRIATKATNFNSSGMLLKLIGFFGFPWLMSRLRVKFLDSELYDFFDNVITETINTR
ERKEITRNDMIDLLLQAKHGKLEYQEEKSSSDGFATVEESQIGKQKVKTVWSNQDLMAQC
FIFFFAGFETVSNVMTFMAYELILNPDIQKKLQDEIDAMNAELKGGDLTYEDVQKLKYMD
MVLCETLRMWPPAPIIDRMCTKDFLLEYDNKKVQIEVGRNFYIPVYSLHHNENYFPNPNR
FDPERFSDENKKNIRQDCYL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g13580.t23 | Gene3D | G3DSA:1.10.630.10 | Cytochrome p450 | 1 | 320 | 3.6E-80 |
| 2 | g13580.t23 | PANTHER | PTHR24292 | CYTOCHROME P450 | 1 | 320 | 1.2E-118 |
| 3 | g13580.t23 | PANTHER | PTHR24292:SF90 | CYTOCHROME P450 317A1-RELATED | 1 | 320 | 1.2E-118 |
| 6 | g13580.t23 | PRINTS | PR00463 | E-class P450 group I signature | 175 | 192 | 9.4E-13 |
| 5 | g13580.t23 | PRINTS | PR00463 | E-class P450 group I signature | 195 | 221 | 9.4E-13 |
| 4 | g13580.t23 | PRINTS | PR00463 | E-class P450 group I signature | 284 | 308 | 9.4E-13 |
| 1 | g13580.t23 | Pfam | PF00067 | Cytochrome P450 | 6 | 317 | 6.1E-52 |
| 11 | g13580.t23 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 1 | 73 | - |
| 14 | g13580.t23 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 74 | 93 | - |
| 12 | g13580.t23 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 94 | 175 | - |
| 13 | g13580.t23 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 176 | 203 | - |
| 10 | g13580.t23 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 204 | 320 | - |
| 8 | g13580.t23 | SUPERFAMILY | SSF48264 | Cytochrome P450 | 2 | 319 | 8.38E-70 |
| 7 | g13580.t23 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 71 | 93 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0020037 | heme binding | MF |
| GO:0016705 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | MF |
| GO:0005506 | iron ion binding | MF |
| GO:0055114 | NA | NA |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
