General information for g13832.t12
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Tyrosine aminotransferase.
Parent gene
- The parent gene g13832 is located on chr_1: 32628734..32630336 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g13832 | g13832.t12 | TTS | g13832.t12 | 32627693 | 32627693 |
| chr_1 | g13832 | g13832.t12 | isoform | g13832.t12 | 32627774 | 32630336 |
| chr_1 | g13832 | g13832.t12 | exon | g13832.t12.exon1 | 32627774 | 32627968 |
| chr_1 | g13832 | g13832.t12 | exon | g13832.t12.exon2 | 32628031 | 32628930 |
| chr_1 | g13832 | g13832.t12 | cds | g13832.t12.CDS1 | 32628167 | 32628930 |
| chr_1 | g13832 | g13832.t12 | exon | g13832.t12.exon3 | 32628995 | 32629138 |
| chr_1 | g13832 | g13832.t12 | cds | g13832.t12.CDS2 | 32628995 | 32629085 |
| chr_1 | g13832 | g13832.t12 | exon | g13832.t12.exon4 | 32629994 | 32630095 |
| chr_1 | g13832 | g13832.t12 | exon | g13832.t12.exon5 | 32630185 | 32630336 |
| chr_1 | g13832 | g13832.t12 | TSS | g13832.t12 | 32630493 | 32630493 |
Sequences
>g13832.t12 Gene=g13832 Length=1493
ATGGCAACGAAAGTCGAACAGACGACTAATGAAGTATTGCATTTTATTGGAAATTTTGGT
GCAAGTGAAAAGCCAAAGCCAATCGACAATAAAAGAAAGCTTCTTCGTCGTCAAAGTACT
GTTCGTGATTTAAGATGGAATGTAAAAATAAGTGGATTCGCTCAAAAAACTCATAATCCG
ATCAGAGCAATTGTAGATGGATTGACAATCGTACCTAATCCTGAAAAAAAAATGATTGCA
CTTTCGATTGGTAAGTGACCCCACAACTTTTGGAAATTTGCTACCTGCGAATGAAATTCT
TGATGCCATGAAAAAAGTTATTGATGATAAAAATTTTAATGGTTATGCACCCTCAGTTGG
ATTCATAGAAGCACGAGAAGCAGTTGCTGAGTATTCCGCTCATCAAGGAGTCATAAAAGA
AATTTCTGCAAAAGATGTAATTTTGTGTTCAGGCTGCAGTTGTGCACTCGATCTTTGCAT
AGCTGCAATTGCCAATGAAGGACAAAATATTTTGATTCCAAAGCCAGGATTTTCAATTTA
CAGAACTTTAGCGGAAGGTTTTGGAATCGAATGTCGTTCATATAATTTAATTCCAGAGCA
AGGTTGGGAAATTGATTTGGATCATTTGGAAGAATTAATTGATGAAAATACTGCCGCCAT
TATTGTTACCAATCCATCAAATCCTTGTGGCAGTGTGTTCAGTAAGCAACACATTTTAGA
TATTTTAGAGATTGCTGAGCGTCACTATGTACCTATTATTGCTGATGAAATTTATGAACA
TTTTGTATTTCCTGGCAATGAATATTTTTCAATGGCTTCATTGTCAAAAAATGTACCTAT
ATTAAGCTGTGGTGGTACTACTAAACGATTTTTAGTGCCAGGTTGGCGTTTGGGATGGAT
TATTGTTCATGATCGTCATGGAGCATTTAGTGAAGTCAGACAGGGACTCTTAAATTTATC
GGCCAGAATTTTAGGTCCAAATTCACTTGTGCAAGGAGCACTGCCAGCAATTCTTAAAAA
TACTCCACAAAAGTTTTATGATGAACTTGTTGAGACACTTCAAAATCATGCTAATATTGC
TTATTCAATGTTAAAAGAAATTCCTGGTTTAACACCAATTATGCCACAAGGTGCAATGTA
TATGATGGTTCTCCGTACGTAGTTTACATCTTCATTAATTATTTATTTAAAACTTTTTTA
TTTATTTTTTATTAACCTTTATTATTACAGTGGATATGAAAAATTTTCCGGAGTTTCATG
ATGAACTTGATTTTGTTCAATCTCTTGTGGCTGAGCAAAGTGTCTTTTGTCTTCCCGGAA
AATGTTTCGATATTGATGATTTCATACGGATTGTACTAACAGTTCCAAAAGAGATGATCA
TCGAAGCATGTGAACGAATTCAAGAGTTTTGTGAAAATCATTATCGACCCCCAAAAATTG
ATGAAGAAATTGACGATCTTGCAACAAATTTTATTAAAATTACAGATTTTTGA
>g13832.t12 Gene=g13832 Length=284
MKKVIDDKNFNGYAPSVGFIEAREAVAEYSAHQGVIKEISAKDVILCSGCSCALDLCIAA
IANEGQNILIPKPGFSIYRTLAEGFGIECRSYNLIPEQGWEIDLDHLEELIDENTAAIIV
TNPSNPCGSVFSKQHILDILEIAERHYVPIIADEIYEHFVFPGNEYFSMASLSKNVPILS
CGGTTKRFLVPGWRLGWIIVHDRHGAFSEVRQGLLNLSARILGPNSLVQGALPAILKNTP
QKFYDELVETLQNHANIAYSMLKEIPGLTPIMPQGAMYMMVLRT
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g13832.t12 | CDD | cd00609 | AAT_like | 1 | 281 | 2.60902E-75 |
| 7 | g13832.t12 | Gene3D | G3DSA:3.40.640.10 | - | 1 | 234 | 9.9E-69 |
| 6 | g13832.t12 | Gene3D | G3DSA:3.90.1150.10 | Aspartate Aminotransferase | 235 | 282 | 3.3E-7 |
| 2 | g13832.t12 | PANTHER | PTHR45744 | TYROSINE AMINOTRANSFERASE | 2 | 281 | 1.6E-119 |
| 3 | g13832.t12 | PANTHER | PTHR45744:SF2 | TYROSINE AMINOTRANSFERASE | 2 | 281 | 1.6E-119 |
| 1 | g13832.t12 | Pfam | PF00155 | Aminotransferase class I and II | 4 | 281 | 3.8E-58 |
| 5 | g13832.t12 | ProSitePatterns | PS00105 | Aminotransferases class-I pyridoxal-phosphate attachment site. | 183 | 196 | - |
| 4 | g13832.t12 | SUPERFAMILY | SSF53383 | PLP-dependent transferases | 4 | 281 | 7.1E-70 |
| 8 | g13832.t12 | TIGRFAM | TIGR01265 | tyr_nico_aTase: tyrosine/nicotianamine family aminotransferase | 1 | 281 | 1.4E-124 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0009058 | biosynthetic process | BP |
| GO:0006520 | cellular amino acid metabolic process | BP |
| GO:0008483 | transaminase activity | MF |
| GO:0003824 | catalytic activity | MF |
| GO:0030170 | pyridoxal phosphate binding | MF |
KEGG
Orthology
- This transcript has been annotated with K00812 (aspartate aminotransferase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed