General information for g1392.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Glutamyl aminopeptidase.
Parent gene
- The parent gene g1392 is located on chr_3: 10624726..10626545 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g1392 | g1392.t1 | TTS | g1392.t1 | 10622801 | 10622801 |
| chr_3 | g1392 | g1392.t1 | isoform | g1392.t1 | 10622879 | 10626545 |
| chr_3 | g1392 | g1392.t1 | exon | g1392.t1.exon1 | 10622879 | 10623530 |
| chr_3 | g1392 | g1392.t1 | cds | g1392.t1.CDS1 | 10622879 | 10623530 |
| chr_3 | g1392 | g1392.t1 | exon | g1392.t1.exon2 | 10623587 | 10624374 |
| chr_3 | g1392 | g1392.t1 | cds | g1392.t1.CDS2 | 10623587 | 10624374 |
| chr_3 | g1392 | g1392.t1 | exon | g1392.t1.exon3 | 10624432 | 10624665 |
| chr_3 | g1392 | g1392.t1 | cds | g1392.t1.CDS3 | 10624432 | 10624665 |
| chr_3 | g1392 | g1392.t1 | exon | g1392.t1.exon4 | 10624726 | 10624848 |
| chr_3 | g1392 | g1392.t1 | cds | g1392.t1.CDS4 | 10624726 | 10624848 |
| chr_3 | g1392 | g1392.t1 | exon | g1392.t1.exon5 | 10624907 | 10624922 |
| chr_3 | g1392 | g1392.t1 | cds | g1392.t1.CDS5 | 10624907 | 10624922 |
| chr_3 | g1392 | g1392.t1 | exon | g1392.t1.exon6 | 10625009 | 10625039 |
| chr_3 | g1392 | g1392.t1 | cds | g1392.t1.CDS6 | 10625009 | 10625039 |
| chr_3 | g1392 | g1392.t1 | exon | g1392.t1.exon7 | 10625106 | 10625524 |
| chr_3 | g1392 | g1392.t1 | cds | g1392.t1.CDS7 | 10625106 | 10625524 |
| chr_3 | g1392 | g1392.t1 | exon | g1392.t1.exon8 | 10625615 | 10626209 |
| chr_3 | g1392 | g1392.t1 | cds | g1392.t1.CDS8 | 10625615 | 10626209 |
| chr_3 | g1392 | g1392.t1 | exon | g1392.t1.exon9 | 10626401 | 10626545 |
| chr_3 | g1392 | g1392.t1 | cds | g1392.t1.CDS9 | 10626401 | 10626545 |
| chr_3 | g1392 | g1392.t1 | TSS | g1392.t1 | NA | NA |
Sequences
>g1392.t1 Gene=g1392 Length=3003
ATGCCAAATCAAAATAATTTAATTAGACCATCAAGTTATAGCTCTTCTTCAAAGCAGCAT
CTTGATAAAGTTGAGCTATCTAGGAAAAGAACATCCATTTTAATATTAACGTTGATATCA
TTAGTCATATTTTTATTCATTTTATCTTTATTGTTAATCTGTGCATTAGTAGTTGTTGGA
AAAGGTTTATCACAAAAAAACGATAGCCTATCGGACATAAATACTCAGCAAACAGTTTCA
AGTATTTCATTGATAAATCATTTGTCGAATAATATTAATAAGAACAAAATTGATACGAGT
ACTGAATCAAAGTTTAGTGTGAACGGAAACAGCATGAGTATGAATAGAATTGTAGACAAT
TTAACATTTCGTTTACCACGGCAAATTACACCATCACTTTACAACTTATTTCTTCATCCT
GATCTAAAGAAAAAGACATTTAGAGGAAATGTAAAAATTGATATTCAAGTCTCAGAACAA
ATGCCATTCCTTGCACTCCATTCAAAATTTCTTAACATCACGCAAGTAAAGTTGATGAAA
AGTTTAGTCAATGGAAAAGAAGGATTGAATGTGAAGAATTCATTCATGTATGATAAATTT
GAGTTCTTTATCATTGAGCCAGAACAGCCACTTGCTGTCGGAAATTATACGGTTGACTTA
GATTTTGAAGGCTCACTTGATGGAAAAATTGTTGGTTTTTACGGAAGTTCATATTTAGAT
AAAATGAAAAATCAAACGAGGTATATTGCAACATCTAAATTTGAACCAACATTTGCTCGA
CAATCTTTCCCGTGCTTTGATGAACCTTCCATGAAAGCAAAATTTAAAATTTCATTGATA
AGTCCAAAAGATGATGGATATCATGCTTTATCAAACATGAATGTAGAATCAATTGAAGAT
TATGATGAAAACTTCATGAAATATAACTTTTTTGAGTCCGTTCCTATGTCAACATACCTC
ACAGTATTTATTGTGTCAAATTTTCAAAATAAGTCACAAATGGTAAATGTTAATTCTACT
ATTGGTGAGCCATTCTTACTGAGCGTTTACTCAACACCTCAACAAATCGATAAGACTGAT
TATGCTCTTGAAACAGCAAAGAAAGTTATTGAGTACTACATTCAATACTTTAATATAAAA
TATCCATTACCTAAATTAGATCTTGCTGCTATACCAGATTTTGTTAGTGGAGCTATGGAA
ACTTGGGGCTTAGTAACATACAGAGAAACAAATTTGCTTTATGATGCAAAAGTAAGTTCA
ACAGCAAACAAGCAGAGAATTGCATCAGTTATTTCACATGAATTAGCGCATATGTATTTT
GGAAATTTGGTGAGCATGCGATGGTGGAATGACTTATTTTTGAATGAAGGTTTTGCATCA
TACATTGAATTCAAAGGAGAAATGGCCGCAGAGGAAGATTGGGATATGATGTCTCAATTT
ACAATTGATACAATGCATAGTGTTTTAGATTTAGATGCAACACTTGGCTCTCATCCTATT
GTTGTTGGGGTTGAAACTCCCGATCAAATCACAGAAATTTTTGATTCTATCACATACAAT
AAGGGTGCATCTGTTATAAGAATGATTGAAGATTTTGTTGGTGAAGAAAATTTCCGTAAA
GGAGTGACAGAATATTTAAATGAGAAACGTTTTGGAAATGCTGATGCTGATGATTTGTTG
AGAAACTTGAAACCATTTACAGATTTAGATATATTCAGTATTGTCAATACTTTTATTCGT
CAAAAAGGTATTGCAGTTGTAACAGTTGAGAAAATCGGAAATGAACTTCATCTCACACAA
AAACGTTTCCTCACTGATCCAGAAAGTGAAAGTCAAGAGACACTTGCATCTGAATATAAT
TATAAATGGTCACTTCCAATCACTTATTTTACAAATAATAATAAAACTGTTCAACGTGAA
TGGTTCTATCATACTGCAGAAAAGCTCATTATTCCAATTGATGATGCTGATTGGGTGAAA
GTGAACAAAGATCAAATTGGCTATTATCGTGTAAATTATGATAAATCAATGTGGGAAAGC
TTGAATGAAGCACTTAAAGCTGATATCAATGTGATGTCTGTATTAGATCGTGCTCACTTA
TTAAATGATGTCTTCAGTCTTGCTCAAGGACAAAAAGTTGATTATGCAACAGCACTGAAA
ATGACTGAATTCTTACAAAAAGAGACGAGCTTCGTGCCATGGGATGCCGTATCGACAAAG
TTGAAAAATATACGAAATCTTCTTTATAACACTGAATATTTTACAGAATTTAAAGATTAT
GTCAACAACCTTGTTGATGCGACTTACAAAAATATCTCATGGGAAGTTAATATCAATGCA
CATCTTGATAATTTAAAACGCATAACTATTCTCGATTTGGCTTGCTCATTTGATCATGTA
GAATGCATGAATGAAGTTGGTATCCGTTTCCGTCAATGGTTAAATAACCCAGACGAACGT
CCTCATCCTGATTTGCGCTCACTTATCTATTATCACGGCATGCGATCAGTTGGTAATAAA
AATGATTGGGATAAGATGTTTGAAATTTTCGCAGCTGAAAATGATGCAACAGAAAAATCT
AAGCTTCAGTCAGCTCTTGCAGCTATTCAAGATCCAGTTATTTTAATGAAATATATTGAG
CTTGCATCAGCAAATGAAACTTATGTGAGAAGTCAAGATTACTTTAATCTTCTTGCATCT
GTTGCTGGCAATCGGGCAGGTGAAATGCTTGTATGGGACTTTGTAAGAATGAATTGGGAA
AAATTGGTTCAAAAGTTCACATTGAATGAAAGAAATTTAGGAAGAATGATTCCTAATGTA
ACAAATAAATTTTCAAGTGAAATTCGCTTAAAAGAAATGCAAAATTTCTTCAATGAGTAT
CCTGAAGCAGGTGCAGGAGCGAACGCGCGGAAGCAAGCTCTTGAGAATATTCAAAATAAC
ATAAAATGGTTGAAAAATAACAAGCAATCAATTGGTGATTTCTTGCAAAGTTTGAACTTG
TAA
>g1392.t1 Gene=g1392 Length=1000
MPNQNNLIRPSSYSSSSKQHLDKVELSRKRTSILILTLISLVIFLFILSLLLICALVVVG
KGLSQKNDSLSDINTQQTVSSISLINHLSNNINKNKIDTSTESKFSVNGNSMSMNRIVDN
LTFRLPRQITPSLYNLFLHPDLKKKTFRGNVKIDIQVSEQMPFLALHSKFLNITQVKLMK
SLVNGKEGLNVKNSFMYDKFEFFIIEPEQPLAVGNYTVDLDFEGSLDGKIVGFYGSSYLD
KMKNQTRYIATSKFEPTFARQSFPCFDEPSMKAKFKISLISPKDDGYHALSNMNVESIED
YDENFMKYNFFESVPMSTYLTVFIVSNFQNKSQMVNVNSTIGEPFLLSVYSTPQQIDKTD
YALETAKKVIEYYIQYFNIKYPLPKLDLAAIPDFVSGAMETWGLVTYRETNLLYDAKVSS
TANKQRIASVISHELAHMYFGNLVSMRWWNDLFLNEGFASYIEFKGEMAAEEDWDMMSQF
TIDTMHSVLDLDATLGSHPIVVGVETPDQITEIFDSITYNKGASVIRMIEDFVGEENFRK
GVTEYLNEKRFGNADADDLLRNLKPFTDLDIFSIVNTFIRQKGIAVVTVEKIGNELHLTQ
KRFLTDPESESQETLASEYNYKWSLPITYFTNNNKTVQREWFYHTAEKLIIPIDDADWVK
VNKDQIGYYRVNYDKSMWESLNEALKADINVMSVLDRAHLLNDVFSLAQGQKVDYATALK
MTEFLQKETSFVPWDAVSTKLKNIRNLLYNTEYFTEFKDYVNNLVDATYKNISWEVNINA
HLDNLKRITILDLACSFDHVECMNEVGIRFRQWLNNPDERPHPDLRSLIYYHGMRSVGNK
NDWDKMFEIFAAENDATEKSKLQSALAAIQDPVILMKYIELASANETYVRSQDYFNLLAS
VAGNRAGEMLVWDFVRMNWEKLVQKFTLNERNLGRMIPNVTNKFSSEIRLKEMQNFFNEY
PEAGAGANARKQALENIQNNIKWLKNNKQSIGDFLQSLNL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 21 | g1392.t1 | CDD | cd09601 | M1_APN-Q_like | 134 | 580 | 0.0 |
| 17 | g1392.t1 | Coils | Coil | Coil | 967 | 987 | - |
| 14 | g1392.t1 | Gene3D | G3DSA:2.60.40.1730 | tricorn interacting facor f3 domain | 112 | 328 | 1.2E-61 |
| 15 | g1392.t1 | Gene3D | G3DSA:1.10.390.60 | - | 336 | 583 | 1.5E-96 |
| 13 | g1392.t1 | Gene3D | G3DSA:2.60.40.1910 | - | 585 | 673 | 2.5E-22 |
| 16 | g1392.t1 | Gene3D | G3DSA:1.25.50.20 | - | 675 | 999 | 4.1E-98 |
| 4 | g1392.t1 | PANTHER | PTHR11533:SF273 | AMINOPEPTIDASE-RELATED | 61 | 996 | 0.0 |
| 5 | g1392.t1 | PANTHER | PTHR11533 | PROTEASE M1 ZINC METALLOPROTEASE | 61 | 996 | 0.0 |
| 6 | g1392.t1 | PRINTS | PR00756 | Membrane alanyl dipeptidase (M1) family signature | 260 | 275 | 6.8E-25 |
| 9 | g1392.t1 | PRINTS | PR00756 | Membrane alanyl dipeptidase (M1) family signature | 310 | 325 | 6.8E-25 |
| 10 | g1392.t1 | PRINTS | PR00756 | Membrane alanyl dipeptidase (M1) family signature | 394 | 404 | 6.8E-25 |
| 8 | g1392.t1 | PRINTS | PR00756 | Membrane alanyl dipeptidase (M1) family signature | 430 | 445 | 6.8E-25 |
| 7 | g1392.t1 | PRINTS | PR00756 | Membrane alanyl dipeptidase (M1) family signature | 449 | 461 | 6.8E-25 |
| 3 | g1392.t1 | Pfam | PF17900 | Peptidase M1 N-terminal domain | 131 | 320 | 9.3E-48 |
| 2 | g1392.t1 | Pfam | PF01433 | Peptidase family M1 domain | 361 | 578 | 1.7E-76 |
| 1 | g1392.t1 | Pfam | PF11838 | ERAP1-like C-terminal domain | 658 | 978 | 6.0E-76 |
| 18 | g1392.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 1 | 32 | - |
| 20 | g1392.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 33 | 59 | - |
| 19 | g1392.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 60 | 1000 | - |
| 12 | g1392.t1 | SUPERFAMILY | SSF63737 | Leukotriene A4 hydrolase N-terminal domain | 116 | 326 | 5.62E-49 |
| 11 | g1392.t1 | SUPERFAMILY | SSF55486 | Metalloproteases (zincins), catalytic domain | 346 | 590 | 4.15E-78 |
| 22 | g1392.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 38 | 60 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0008237 | metallopeptidase activity | MF |
| GO:0006508 | proteolysis | BP |
| GO:0008270 | zinc ion binding | MF |
KEGG
Orthology
- This transcript has been annotated with K11141 (glutamyl aminopeptidase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
