General information for g14005.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Activating transcription factor of chaperone.
Parent gene
- The parent gene g14005 is located on chr_1: 33965851..33967151 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g14005 | g14005.t1 | TSS | g14005.t1 | 33961789 | 33961789 |
| chr_1 | g14005 | g14005.t1 | isoform | g14005.t1 | 33961926 | 33966740 |
| chr_1 | g14005 | g14005.t1 | exon | g14005.t1.exon1 | 33961926 | 33961936 |
| chr_1 | g14005 | g14005.t1 | cds | g14005.t1.CDS1 | 33961926 | 33961936 |
| chr_1 | g14005 | g14005.t1 | exon | g14005.t1.exon2 | 33962699 | 33962802 |
| chr_1 | g14005 | g14005.t1 | cds | g14005.t1.CDS2 | 33962699 | 33962802 |
| chr_1 | g14005 | g14005.t1 | exon | g14005.t1.exon3 | 33962864 | 33962959 |
| chr_1 | g14005 | g14005.t1 | cds | g14005.t1.CDS3 | 33962864 | 33962959 |
| chr_1 | g14005 | g14005.t1 | exon | g14005.t1.exon4 | 33963026 | 33963109 |
| chr_1 | g14005 | g14005.t1 | cds | g14005.t1.CDS4 | 33963026 | 33963109 |
| chr_1 | g14005 | g14005.t1 | exon | g14005.t1.exon5 | 33965851 | 33966740 |
| chr_1 | g14005 | g14005.t1 | cds | g14005.t1.CDS5 | 33965851 | 33966740 |
| chr_1 | g14005 | g14005.t1 | TTS | g14005.t1 | 33967151 | 33967151 |
Sequences
>g14005.t1 Gene=g14005 Length=1185
ATGCGTTTCGAACCAAATTTATCAGCCGCCATGGCTACTTTTACACAACAAGAAGAAAGT
TTTACAAACGACTCCAGCTTCTATACATACAACAAATTGACAGATCGGATATCAACTCTG
TTATTCGAAAAAATGATAATGGGCCTTCCATCAGCCTCCGATATGACTACACCCACTGAG
GATATAATATTCGAAGACAACTTCGCTAATGAAATTTATATGAAATACGTTGATGAATCC
CCTGGCATTGATCTTTTTGCGGAAATGGAGCAAGATGATAAAATATATCTTGACGAGTTG
CAGTCGATAACAAACAAGATCGATTTACCCATAAACGATTTTGTTGCATCGATTGAAAAC
CCCGAAGAGTTTGAGAACATCGAAGGATCTAAAAGTGAGCAATTGCTACTTGATTTCAAC
TCCATTTTCGATGGTGTTGAAAATGAATTGACACCACCACAATCACCACCACAATTATTT
ACTTCATCTTTGCAAGAACAACAACAATTTTCACCAAACAACATTCCAGCAACAGTCAAT
AATCAATATGAATTTTTCAACACTTATCAACCAGTTCAACAAGCATTAACACAAGGGGAA
CAGTTTATTTACATTCAAAATGCATCTCCTGCTGCATCCACTCCATCGCAAGGAAATGTA
GAAGTTTCTATCGTTTATGAAAACAACAATCAATCGATTATACCTAGTGATGAAATTATT
TTTGATCCTGACAGCATTATCTCATCACCAACTGACATTCAACGCGAATTAGAAGTTGTT
GATGAATTAGTGCGTGCACATTCACGACAGACTTCGGATTATGAAGAATCAGCATCATCA
TCATGGTCTCCACGTAGTGAATATTCGAGTAGTGGATATTCACAATATGATGATGAACCA
GTTAAAAAATCAAAGTCTGGCTTGAAGGGCGTTACAAAGAAACGTACACGTGGCTATGGA
AGAAATCCAGAAGAAAAGAAATCGCGTAAGAAGGAACAAAATAAGAATGCTGCTACTCGC
TATCGTATGAAGAAGAAGCAAAAAGTTGAGGTCATTATGGACGAGGAGAAAATTTTAATG
GATAAGAACAAGAGATTGACAACAGCCTATAAAGATACAAAGCGCGAAGTTAAATACCTG
AAAAGCTTGTTGCGAGATCTTTTCAAAGCTCGCGGATTCATTTAA
>g14005.t1 Gene=g14005 Length=394
MRFEPNLSAAMATFTQQEESFTNDSSFYTYNKLTDRISTLLFEKMIMGLPSASDMTTPTE
DIIFEDNFANEIYMKYVDESPGIDLFAEMEQDDKIYLDELQSITNKIDLPINDFVASIEN
PEEFENIEGSKSEQLLLDFNSIFDGVENELTPPQSPPQLFTSSLQEQQQFSPNNIPATVN
NQYEFFNTYQPVQQALTQGEQFIYIQNASPAASTPSQGNVEVSIVYENNNQSIIPSDEII
FDPDSIISSPTDIQRELEVVDELVRAHSRQTSDYEESASSSWSPRSEYSSSGYSQYDDEP
VKKSKSGLKGVTKKRTRGYGRNPEEKKSRKKEQNKNAATRYRMKKKQKVEVIMDEEKILM
DKNKRLTTAYKDTKREVKYLKSLLRDLFKARGFI
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 5 | g14005.t1 | CDD | cd14692 | bZIP_ATF4 | 325 | 386 | 3.8146E-21 |
| 4 | g14005.t1 | Gene3D | G3DSA:1.20.5.170 | - | 325 | 387 | 1.8E-18 |
| 10 | g14005.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 267 | 344 | - |
| 9 | g14005.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 273 | 297 | - |
| 8 | g14005.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 317 | 344 | - |
| 2 | g14005.t1 | PANTHER | PTHR13044 | ACTIVATING TRANSCRIPTION FACTOR ATF 4/5 | 150 | 392 | 2.8E-20 |
| 1 | g14005.t1 | Pfam | PF00170 | bZIP transcription factor | 324 | 383 | 1.5E-6 |
| 6 | g14005.t1 | ProSitePatterns | PS00036 | Basic-leucine zipper (bZIP) domain signature. | 329 | 344 | - |
| 11 | g14005.t1 | ProSiteProfiles | PS50217 | Basic-leucine zipper (bZIP) domain profile. | 324 | 387 | 10.45 |
| 7 | g14005.t1 | SMART | SM00338 | brlzneu | 322 | 386 | 1.4E-11 |
| 3 | g14005.t1 | SUPERFAMILY | SSF57959 | Leucine zipper domain | 332 | 385 | 1.19E-8 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0006355 | regulation of transcription, DNA-templated | BP |
| GO:0003700 | DNA-binding transcription factor activity | MF |
KEGG
Orthology
- This transcript has been annotated with K04374 (cyclic AMP-dependent transcription factor ATF-4)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed