Gene loci information

Transcript annotation

  • This transcript has been annotated as Putative GTP:AMP phosphotransferase AK3, mitochondrial.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g14018 g14018.t8 TTS g14018.t8 34093640 34093640
chr_1 g14018 g14018.t8 isoform g14018.t8 34093892 34094836
chr_1 g14018 g14018.t8 exon g14018.t8.exon1 34093892 34094187
chr_1 g14018 g14018.t8 cds g14018.t8.CDS1 34093892 34094187
chr_1 g14018 g14018.t8 exon g14018.t8.exon2 34094260 34094581
chr_1 g14018 g14018.t8 cds g14018.t8.CDS2 34094260 34094389
chr_1 g14018 g14018.t8 exon g14018.t8.exon3 34094806 34094836
chr_1 g14018 g14018.t8 TSS g14018.t8 34094956 34094956

Sequences

>g14018.t8 Gene=g14018 Length=649
ATGTCAAAGTTATTTCGTGCATTAATAATGGTAAATTTTTCAGGGAAAAGGAACGATAGC
ATCAAGAATATTAAAAAATTTTAATATTACACATCTCAGTACAGGAGATGTACTTAGGAA
TAATATTGAAAAACTCACACCATTAGGAATTGAGGCGGAAACTTATATAAGAAAAGGTGC
TTTAGTGCCAGATGACAGCATGATCAAATGTATCTTAGAAGAAATGAAAGACATCAATGG
ATCATTTCTTCTTGATGGTTTTCCAAGAACAAAAACACAAGCTGAAAAACTTTGGGAAGT
GCAAAAAATTGACTCTGTTATCAATTTAGTCGTGCCATATGAAATTATTATCGATCGTGT
GAAGCTTCGATATGTCCACATGCCAAGTGGAAGAGTTTATAATCTCGACTATAATCCGCC
AAAAGAACCTATGAAAGACGATGTAACGGGAGAACCACTTACTAAAAGAGAAGATGACGA
TCCAGATATTCTATTGAAACGTTTAAAAGTTTATGATGATCAAACAATTCCAGTGTTGGA
ATTTTACAAATCAAAGGGAATTTTGAATGAATTTAAAGGCAACACATCAGATGAAATTTG
GGCAAAATTGCAACCATTCTTGAATGCTGAAATCAATGGAAAAAATTAA

>g14018.t8 Gene=g14018 Length=141
MKDINGSFLLDGFPRTKTQAEKLWEVQKIDSVINLVVPYEIIIDRVKLRYVHMPSGRVYN
LDYNPPKEPMKDDVTGEPLTKREDDDPDILLKRLKVYDDQTIPVLEFYKSKGILNEFKGN
TSDEIWAKLQPFLNAEINGKN

Protein features from InterProScan

Transcript Database ID Name Start End E.value
11 g14018.t8 CDD cd01428 ADK 2 122 1.6719E-38
10 g14018.t8 Gene3D G3DSA:3.40.50.300 - 2 141 1.5E-43
5 g14018.t8 Hamap MF_00235 Adenylate kinase [adk]. 2 134 23.470232
14 g14018.t8 MobiDBLite mobidb-lite consensus disorder prediction 62 82 -
13 g14018.t8 MobiDBLite mobidb-lite consensus disorder prediction 66 82 -
3 g14018.t8 PANTHER PTHR23359 NUCLEOTIDE KINASE 7 138 1.3E-43
4 g14018.t8 PANTHER PTHR23359:SF68 GTP:AMP PHOSPHOTRANSFERASE AK3, MITOCHONDRIAL 7 138 1.3E-43
8 g14018.t8 PRINTS PR00094 Adenylate kinase signature 8 24 3.7E-15
7 g14018.t8 PRINTS PR00094 Adenylate kinase signature 82 97 3.7E-15
6 g14018.t8 PRINTS PR00094 Adenylate kinase signature 99 113 3.7E-15
2 g14018.t8 Pfam PF00406 Adenylate kinase 4 112 2.1E-16
1 g14018.t8 Pfam PF05191 Adenylate kinase, active site lid 49 84 1.6E-14
12 g14018.t8 ProSitePatterns PS00113 Adenylate kinase signature. 8 19 -
9 g14018.t8 SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases 5 135 2.12E-12

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0005524 ATP binding MF
GO:0006139 nucleobase-containing compound metabolic process BP
GO:0004017 adenylate kinase activity MF
GO:0019205 nucleobase-containing compound kinase activity MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed