General information for g14020.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative GTP:AMP phosphotransferase AK3, mitochondrial.
Parent gene
- The parent gene g14020 is located on chr_1: 34096648..34097600 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g14020 | g14020.t1 | TTS | g14020.t1 | 34096509 | 34096509 |
| chr_1 | g14020 | g14020.t1 | isoform | g14020.t1 | 34096648 | 34097600 |
| chr_1 | g14020 | g14020.t1 | exon | g14020.t1.exon1 | 34096648 | 34096874 |
| chr_1 | g14020 | g14020.t1 | cds | g14020.t1.CDS1 | 34096648 | 34096874 |
| chr_1 | g14020 | g14020.t1 | exon | g14020.t1.exon2 | 34096979 | 34097035 |
| chr_1 | g14020 | g14020.t1 | cds | g14020.t1.CDS2 | 34096979 | 34097035 |
| chr_1 | g14020 | g14020.t1 | exon | g14020.t1.exon3 | 34097097 | 34097406 |
| chr_1 | g14020 | g14020.t1 | cds | g14020.t1.CDS3 | 34097097 | 34097406 |
| chr_1 | g14020 | g14020.t1 | exon | g14020.t1.exon4 | 34097487 | 34097500 |
| chr_1 | g14020 | g14020.t1 | cds | g14020.t1.CDS4 | 34097487 | 34097500 |
| chr_1 | g14020 | g14020.t1 | exon | g14020.t1.exon5 | 34097570 | 34097600 |
| chr_1 | g14020 | g14020.t1 | cds | g14020.t1.CDS5 | 34097570 | 34097600 |
| chr_1 | g14020 | g14020.t1 | TSS | g14020.t1 | 34097632 | 34097632 |
Sequences
>g14020.t1 Gene=g14020 Length=639
ATGTCAAAATTATTTCGAGCAGTTCTATTAGGAGCTCCAGGAGCTGGAAAGAAGAGAATT
GCGTCGCAAATATTAGAGTGTTTTAATATAACACATATAAACATCGGTGATGTCTTGAGA
AATAATGTTGAGAAACTTAGCCCATTGGGTGTGGATATAGAAAAATATGTTAATAAAGGA
GCACTTTTGCCAGATGATGACATGCTTAAAATTGTTCTCAAAGAGATAAATGATATTCAT
GGATCATTTTTTCTTGATGGTTTTCCAAGAACAAAAACACAAGCTGAAAAACTTTGGGAA
GTGCAAAAAATTGATTCTGTTATCAATTTAGTCGTACCGAAAGATGTGATTATAGATGAT
GCTAAGCATCGATATGTTCATGAGCCAAGTGGAAGAGTTTATAATATTAAAGAAAATGCC
ATGAAAACTGATATCACAGGAGAACCATTGTCAAAGCAAGATTATGATGAACCAGAAGTT
ACTGAAAAATGGTTGAAATTTTATAAGGAACAAACTACTCCAATGATTGAATTTTACAAG
TTAAAAGGAATCTTCAATGAATTTGAGGGAGAAACAACTCACGAAATATGGGAAAAACTA
AAACCATTTTTAAGCGAAAGAGTCGATAAACAAAAATAA
>g14020.t1 Gene=g14020 Length=212
MSKLFRAVLLGAPGAGKKRIASQILECFNITHINIGDVLRNNVEKLSPLGVDIEKYVNKG
ALLPDDDMLKIVLKEINDIHGSFFLDGFPRTKTQAEKLWEVQKIDSVINLVVPKDVIIDD
AKHRYVHEPSGRVYNIKENAMKTDITGEPLSKQDYDEPEVTEKWLKFYKEQTTPMIEFYK
LKGIFNEFEGETTHEIWEKLKPFLSERVDKQK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 17 | g14020.t1 | CDD | cd01428 | ADK | 6 | 193 | 2.26535E-59 |
| 11 | g14020.t1 | Gene3D | G3DSA:3.40.50.300 | - | 2 | 212 | 1.1E-57 |
| 4 | g14020.t1 | Hamap | MF_00235 | Adenylate kinase [adk]. | 5 | 205 | 29.647512 |
| 2 | g14020.t1 | PANTHER | PTHR23359 | NUCLEOTIDE KINASE | 4 | 210 | 1.9E-47 |
| 3 | g14020.t1 | PANTHER | PTHR23359:SF68 | GTP:AMP PHOSPHOTRANSFERASE AK3, MITOCHONDRIAL | 4 | 210 | 1.9E-47 |
| 9 | g14020.t1 | PRINTS | PR00094 | Adenylate kinase signature | 8 | 21 | 1.5E-21 |
| 7 | g14020.t1 | PRINTS | PR00094 | Adenylate kinase signature | 36 | 50 | 1.5E-21 |
| 5 | g14020.t1 | PRINTS | PR00094 | Adenylate kinase signature | 83 | 99 | 1.5E-21 |
| 6 | g14020.t1 | PRINTS | PR00094 | Adenylate kinase signature | 153 | 168 | 1.5E-21 |
| 8 | g14020.t1 | PRINTS | PR00094 | Adenylate kinase signature | 170 | 184 | 1.5E-21 |
| 1 | g14020.t1 | Pfam | PF00406 | Adenylate kinase | 9 | 183 | 1.0E-32 |
| 13 | g14020.t1 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 16 | - |
| 14 | g14020.t1 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 3 | - |
| 15 | g14020.t1 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 4 | 11 | - |
| 16 | g14020.t1 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 12 | 16 | - |
| 12 | g14020.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 17 | 212 | - |
| 18 | g14020.t1 | ProSitePatterns | PS00113 | Adenylate kinase signature. | 83 | 94 | - |
| 10 | g14020.t1 | SUPERFAMILY | SSF52540 | P-loop containing nucleoside triphosphate hydrolases | 2 | 206 | 1.59E-24 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005524 | ATP binding | MF |
| GO:0006139 | nucleobase-containing compound metabolic process | BP |
| GO:0019205 | nucleobase-containing compound kinase activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
