General information for g14041.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as ATP-binding cassette sub-family G member 4.
Parent gene
- The parent gene g14041 is located on chr_1: 34274777..34281707 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g14041 | g14041.t1 | TSS | g14041.t1 | 34274652 | 34274652 |
| chr_1 | g14041 | g14041.t1 | isoform | g14041.t1 | 34274777 | 34281707 |
| chr_1 | g14041 | g14041.t1 | exon | g14041.t1.exon1 | 34274777 | 34275035 |
| chr_1 | g14041 | g14041.t1 | cds | g14041.t1.CDS1 | 34274777 | 34275035 |
| chr_1 | g14041 | g14041.t1 | exon | g14041.t1.exon2 | 34276424 | 34276489 |
| chr_1 | g14041 | g14041.t1 | cds | g14041.t1.CDS2 | 34276424 | 34276489 |
| chr_1 | g14041 | g14041.t1 | exon | g14041.t1.exon3 | 34276569 | 34276583 |
| chr_1 | g14041 | g14041.t1 | cds | g14041.t1.CDS3 | 34276569 | 34276583 |
| chr_1 | g14041 | g14041.t1 | exon | g14041.t1.exon4 | 34276639 | 34276728 |
| chr_1 | g14041 | g14041.t1 | cds | g14041.t1.CDS4 | 34276639 | 34276728 |
| chr_1 | g14041 | g14041.t1 | exon | g14041.t1.exon5 | 34276789 | 34276925 |
| chr_1 | g14041 | g14041.t1 | cds | g14041.t1.CDS5 | 34276789 | 34276925 |
| chr_1 | g14041 | g14041.t1 | exon | g14041.t1.exon6 | 34278612 | 34278757 |
| chr_1 | g14041 | g14041.t1 | cds | g14041.t1.CDS6 | 34278612 | 34278757 |
| chr_1 | g14041 | g14041.t1 | exon | g14041.t1.exon7 | 34278817 | 34279055 |
| chr_1 | g14041 | g14041.t1 | cds | g14041.t1.CDS7 | 34278817 | 34279055 |
| chr_1 | g14041 | g14041.t1 | exon | g14041.t1.exon8 | 34279121 | 34279525 |
| chr_1 | g14041 | g14041.t1 | cds | g14041.t1.CDS8 | 34279121 | 34279525 |
| chr_1 | g14041 | g14041.t1 | exon | g14041.t1.exon9 | 34279586 | 34279810 |
| chr_1 | g14041 | g14041.t1 | cds | g14041.t1.CDS9 | 34279586 | 34279810 |
| chr_1 | g14041 | g14041.t1 | exon | g14041.t1.exon10 | 34279872 | 34279903 |
| chr_1 | g14041 | g14041.t1 | cds | g14041.t1.CDS10 | 34279872 | 34279903 |
| chr_1 | g14041 | g14041.t1 | exon | g14041.t1.exon11 | 34281235 | 34281271 |
| chr_1 | g14041 | g14041.t1 | cds | g14041.t1.CDS11 | 34281235 | 34281271 |
| chr_1 | g14041 | g14041.t1 | exon | g14041.t1.exon12 | 34281345 | 34281507 |
| chr_1 | g14041 | g14041.t1 | cds | g14041.t1.CDS12 | 34281345 | 34281507 |
| chr_1 | g14041 | g14041.t1 | exon | g14041.t1.exon13 | 34281566 | 34281707 |
| chr_1 | g14041 | g14041.t1 | cds | g14041.t1.CDS13 | 34281566 | 34281707 |
| chr_1 | g14041 | g14041.t1 | TTS | g14041.t1 | NA | NA |
Sequences
>g14041.t1 Gene=g14041 Length=1956
ATGGAACTAATACAGGAATCAAATTTAAACACAATTGCGGCACTTTCAATGTCTGCAATG
AAAGTTGATAACAATCATACAACTATCAATAAGCACGTTCAAACGGAATACGTAAAGGGA
TCAATGGACGCAACAGTCATTGATTACCAACATTCACCATCAGCTGTTCGTGCTGCCTTT
CATAACATGCCTGTATGTGAGCCAATAGAAATCTCTTTCAAGGATGTTTCTTATTCCGTT
CAAAAAATGTTTTCTAAAACTCGTAAGGAAATTTTACATAGAGTGAGCGGTAACTTTCCA
AGTGGAAATCTCATCGCAATAATGGGACCGAGTGGTGCTGGAAAGTCAACACTACTCAAC
GCCCTTTCTGGCTACAAAACGAGAAATGTAAGCGGCGCAATTTATGTGAATGGAAGAATT
CGTGATTTAAATGAATTTAAGAAATCAACCTGTTACATTACTCAAGATGATAGACTGCAA
CTGCTTCTAACAGTATACGAGAATATGAAAGTAGCTGCAGATTTGAAACTCGGAAATAAC
GTCAGTGAGATGGAGAAGAATGGCAGAATCGAAAATATTCTTACAGCACTTGGTCTTTAT
GATCACCAACACACAATGACTGAACGGCTGTCAGGTGGACAAAAGAAACGATTATCAGTC
GCACTTGAATTGATAAATAATCCAACTGTCTTATGGCTTGATGAACCCACGACCGGTCTC
GATTCATATTCATGCTGGCAAATGATTGCATATTTGAAACAACTCGCACAGCAAGGACGA
ACTGTCATTTGCACGATTCATCAACCAAGTGCTAAACTTTTTGAGAAATTTGATTTGGTT
TATATTTTAGCGTATGGAAAATGTCTCTACCAAGGTCATTCATCAAAACTCGTTCCATTT
CTTCAATCAGTTTCACTTCCATGTCCGAAATTTCATAATCCTGCTGATTATGCAATTGAA
TTAGCATCAGGTGATTATGGCATGGATAAAGTGAAAACACTCTGTAATTCGATCGGTAAT
GGTGAATGTATTACATGGTATGAAAATCCAAATCGAGTTATGAAATTAGAACAACTTCGT
CAGCAATATCCGATCGGTGAGGAGCGCAAGAAATCTGACGACGTTAGTGAATTGCACAAA
CTCAAAATACTGATACGACGCGGTGTCATCAAAACAAAACGTGATCAGACATTGACCCAT
TTAAGAATCTTCGTCAATATTCTCGTTGCAATATTGCTGGGCTGGCTGTTTATTGGTTCG
GGAACAGATGGCTCACGTGTTCTTGCCAACTATAATCTGATGTTTGCAATTCTTATTCAT
CATGTCTTTTCAACCATGATGCTTACAATTCTAACATTCCCAACAGAAAAATCGACAGTA
CTGAGGGAAAACTTTAATCGATGGTATTCTGTAAAAAGTTATTACATTGCGAACACTCTC
ATCGATTTTCCAGTGACATTTCTTTCATGTCTGCTCTTTTCTATCATTATTTACATCATG
GTTGGTTGGCCAATGGAAGCTGATAGATTTTCTGTGTTCTTCATTGTTAGTTTATTAATT
GTTATGATTGCACAAGCTATAGGTCTAATTATTGGAACATGCTGTAATGTTATTAACGGT
ACATTCTTGGGTCCAATACTCGCTGTACCAGCGATGATGCTAGCGGGATTTGGTGTCACT
TTAAAAGATCTTCCAATGTTTTTAAAGTGGGGAAGTTATGTCTCGTATTTACGTTATGGA
CTTGAAGGTTACGTTGGTGCTCTGTTTTATGAACGAGAACAATTAAAGTGCGATGCTATG
TATTGTCACTACAAATATCCAGATAAGTTTTTAAAGGACATTGCAATGGAAGCTGATAGA
TTCATGCACGATATTGCCGCACTTATTTTCACACTTCTTTTGCTTCGTATCATTTGCTAT
TACTTACTAAAATGGCGCATTGTGCTTAGTCGTTAA
>g14041.t1 Gene=g14041 Length=651
MELIQESNLNTIAALSMSAMKVDNNHTTINKHVQTEYVKGSMDATVIDYQHSPSAVRAAF
HNMPVCEPIEISFKDVSYSVQKMFSKTRKEILHRVSGNFPSGNLIAIMGPSGAGKSTLLN
ALSGYKTRNVSGAIYVNGRIRDLNEFKKSTCYITQDDRLQLLLTVYENMKVAADLKLGNN
VSEMEKNGRIENILTALGLYDHQHTMTERLSGGQKKRLSVALELINNPTVLWLDEPTTGL
DSYSCWQMIAYLKQLAQQGRTVICTIHQPSAKLFEKFDLVYILAYGKCLYQGHSSKLVPF
LQSVSLPCPKFHNPADYAIELASGDYGMDKVKTLCNSIGNGECITWYENPNRVMKLEQLR
QQYPIGEERKKSDDVSELHKLKILIRRGVIKTKRDQTLTHLRIFVNILVAILLGWLFIGS
GTDGSRVLANYNLMFAILIHHVFSTMMLTILTFPTEKSTVLRENFNRWYSVKSYYIANTL
IDFPVTFLSCLLFSIIIYIMVGWPMEADRFSVFFIVSLLIVMIAQAIGLIIGTCCNVING
TFLGPILAVPAMMLAGFGVTLKDLPMFLKWGSYVSYLRYGLEGYVGALFYEREQLKCDAM
YCHYKYPDKFLKDIAMEADRFMHDIAALIFTLLLLRIICYYLLKWRIVLSR
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 21 | g14041.t1 | CDD | cd03213 | ABCG_EPDR | 68 | 292 | 3.9298E-80 |
| 7 | g14041.t1 | Gene3D | G3DSA:3.40.50.300 | - | 69 | 302 | 1.1E-55 |
| 4 | g14041.t1 | PANTHER | PTHR48041:SF26 | FI22810P1 | 22 | 646 | 3.5E-277 |
| 5 | g14041.t1 | PANTHER | PTHR48041 | ABC TRANSPORTER G FAMILY MEMBER 28 | 22 | 646 | 3.5E-277 |
| 3 | g14041.t1 | Pfam | PF00005 | ABC transporter | 92 | 237 | 4.4E-27 |
| 1 | g14041.t1 | Pfam | PF19055 | ABC-2 type transporter | 267 | 326 | 3.6E-5 |
| 2 | g14041.t1 | Pfam | PF01061 | ABC-2 type transporter | 381 | 589 | 2.2E-38 |
| 10 | g14041.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 1 | 402 | - |
| 17 | g14041.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 403 | 421 | - |
| 14 | g14041.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 422 | 432 | - |
| 16 | g14041.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 433 | 453 | - |
| 8 | g14041.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 454 | 473 | - |
| 18 | g14041.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 474 | 500 | - |
| 13 | g14041.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 501 | 511 | - |
| 15 | g14041.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 512 | 535 | - |
| 11 | g14041.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 536 | 541 | - |
| 20 | g14041.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 542 | 561 | - |
| 12 | g14041.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 562 | 624 | - |
| 19 | g14041.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 625 | 643 | - |
| 9 | g14041.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 644 | 651 | - |
| 28 | g14041.t1 | ProSitePatterns | PS00211 | ABC transporters family signature. | 210 | 224 | - |
| 30 | g14041.t1 | ProSiteProfiles | PS50893 | ATP-binding cassette, ABC transporter-type domain profile. | 71 | 310 | 18.227 |
| 29 | g14041.t1 | SMART | SM00382 | AAA_5 | 101 | 289 | 2.7E-14 |
| 6 | g14041.t1 | SUPERFAMILY | SSF52540 | P-loop containing nucleoside triphosphate hydrolases | 71 | 302 | 4.5E-46 |
| 22 | g14041.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 401 | 418 | - |
| 26 | g14041.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 433 | 455 | - |
| 24 | g14041.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 475 | 497 | - |
| 27 | g14041.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 510 | 532 | - |
| 25 | g14041.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 539 | 561 | - |
| 23 | g14041.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 621 | 643 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016020 | membrane | CC |
| GO:0005524 | ATP binding | MF |
| GO:0042626 | ATPase-coupled transmembrane transporter activity | MF |
| GO:0016887 | ATP hydrolysis activity | MF |
KEGG
Orthology
- This transcript has been annotated with K05680 (ATP-binding cassette, subfamily G (WHITE), member 4)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed