General information for g14128.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Glutathione S-transferase T1.
Parent gene
- The parent gene g14128 is located on chr_1: 34832926..34834071 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g14128 | g14128.t1 | TTS | g14128.t1 | 34832096 | 34832096 |
| chr_1 | g14128 | g14128.t1 | isoform | g14128.t1 | 34832128 | 34832926 |
| chr_1 | g14128 | g14128.t1 | exon | g14128.t1.exon1 | 34832128 | 34832662 |
| chr_1 | g14128 | g14128.t1 | cds | g14128.t1.CDS1 | 34832128 | 34832662 |
| chr_1 | g14128 | g14128.t1 | exon | g14128.t1.exon2 | 34832718 | 34832926 |
| chr_1 | g14128 | g14128.t1 | cds | g14128.t1.CDS2 | 34832718 | 34832926 |
| chr_1 | g14128 | g14128.t1 | TSS | g14128.t1 | 34832980 | 34832980 |
Sequences
>g14128.t1 Gene=g14128 Length=744
ATGAAATTTTATTTCGACTTACTTTCACAACCTTCACGTGCATTATACATTTTTCTTAAA
GTCACTAAAACACCAGTTGAGTTTGTTAAAATTGATTTAAAGCGATTAGAGCATTTAACG
AATGAATTTAAAGCAGTGAATAGATTTCAAAAAGTTCCTTGCATTGTTGATAATGGATTC
AAATTATCTGAGTCGGTGGCAATATTTAGATATTTGATGCAATCAAATCCAAATATTTCT
GAAAATTGGTATCCTAAAGATGCAAAATCACGAGCACTTGTTGATGAGTTTCTTGAGTAT
CAACATATTGGTGTCAGATATCCTTGCGCAATTTATTTTCAAACCAAATGGCTTTTACCA
ACTTTCTCAGGCAAACCTCCAAATGAGAAAAAAGTGAGAGAATATGAAAACTTGATGATA
AAGTCACTAGATACATTTGAGAATATTTGGCTTGCAAGTGATCAAAAAGAATTTTTAGCC
ACAAAAGAAATTTCCTTTGCTGATATTTTGGCATGCTGCGAACTTGAGCAACCACGAATG
GCAGACTTTGATACATTTAAAGACCGACCGAGATTGAAAAAGTGGCATGAAAAAGTTAAG
AAAGAAACGAATCCATATTACGATGAAGCACATAAAAATGTTTATGACATAATTCAGTCA
AAAGGAAAACTTTCAAGTAAATTTGATTTGGTTTTCATTTATCGCTACTTGAGATATATA
AAATTCAAAAAATTCTTTGAATAA
>g14128.t1 Gene=g14128 Length=247
MKFYFDLLSQPSRALYIFLKVTKTPVEFVKIDLKRLEHLTNEFKAVNRFQKVPCIVDNGF
KLSESVAIFRYLMQSNPNISENWYPKDAKSRALVDEFLEYQHIGVRYPCAIYFQTKWLLP
TFSGKPPNEKKVREYENLMIKSLDTFENIWLASDQKEFLATKEISFADILACCELEQPRM
ADFDTFKDRPRLKKWHEKVKKETNPYYDEAHKNVYDIIQSKGKLSSKFDLVFIYRYLRYI
KFKKFFE
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 10 | g14128.t1 | CDD | cd03050 | GST_N_Theta | 2 | 72 | 0.0000000 |
| 11 | g14128.t1 | CDD | cd03183 | GST_C_Theta | 91 | 217 | 0.0000000 |
| 7 | g14128.t1 | Gene3D | G3DSA:3.40.30.10 | Glutaredoxin | 1 | 77 | 0.0000000 |
| 6 | g14128.t1 | Gene3D | G3DSA:1.20.1050.10 | - | 80 | 233 | 0.0000000 |
| 3 | g14128.t1 | PANTHER | PTHR43917 | - | 2 | 225 | 0.0000000 |
| 2 | g14128.t1 | Pfam | PF02798 | Glutathione S-transferase, N-terminal domain | 13 | 73 | 0.0000000 |
| 1 | g14128.t1 | Pfam | PF00043 | Glutathione S-transferase, C-terminal domain | 126 | 199 | 0.0000008 |
| 9 | g14128.t1 | ProSiteProfiles | PS50404 | Soluble glutathione S-transferase N-terminal domain profile. | 1 | 80 | 17.2340000 |
| 8 | g14128.t1 | ProSiteProfiles | PS50405 | Soluble glutathione S-transferase C-terminal domain profile. | 87 | 224 | 15.4500000 |
| 12 | g14128.t1 | SFLD | SFLDG00358 | Main (cytGST) | 1 | 201 | 0.0000000 |
| 13 | g14128.t1 | SFLD | SFLDS00019 | Glutathione Transferase (cytosolic) | 1 | 201 | 0.0000000 |
| 4 | g14128.t1 | SUPERFAMILY | SSF52833 | Thioredoxin-like | 1 | 91 | 0.0000000 |
| 5 | g14128.t1 | SUPERFAMILY | SSF47616 | GST C-terminal domain-like | 82 | 212 | 0.0000000 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0006749 | glutathione metabolic process | BP |
| GO:0005515 | protein binding | MF |
KEGG
Orthology
- This transcript has been annotated with K00799 (glutathione S-transferase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
