General information for g14131.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Tyrosine aminotransferase.
Parent gene
- The parent gene g14131 is located on chr_1: 34838871..34839437 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g14131 | g14131.t1 | TSS | g14131.t1 | 34838038 | 34838038 |
| chr_1 | g14131 | g14131.t1 | isoform | g14131.t1 | 34838080 | 34839437 |
| chr_1 | g14131 | g14131.t1 | exon | g14131.t1.exon1 | 34838080 | 34838797 |
| chr_1 | g14131 | g14131.t1 | cds | g14131.t1.CDS1 | 34838080 | 34838797 |
| chr_1 | g14131 | g14131.t1 | exon | g14131.t1.exon2 | 34838855 | 34839072 |
| chr_1 | g14131 | g14131.t1 | cds | g14131.t1.CDS2 | 34838855 | 34839072 |
| chr_1 | g14131 | g14131.t1 | exon | g14131.t1.exon3 | 34839126 | 34839437 |
| chr_1 | g14131 | g14131.t1 | cds | g14131.t1.CDS3 | 34839126 | 34839437 |
| chr_1 | g14131 | g14131.t1 | TTS | g14131.t1 | 34839477 | 34839477 |
Sequences
>g14131.t1 Gene=g14131 Length=1248
ATGGCTGCATCAAAAATTATTAAAAAATGGAATATTTTACCTACTGAATTTTCTAAAAAT
TCCATTAATCCATTAAGACTTTTATGGGAGACTCAACAGCCGAAAGGAAATCCTAAATTG
AAAGAAATTCATTTGCAGCCAGGTGATCCAACTCTTTATGGAAATTTTCCACCTCACCCG
ATTATTGCAAAAGCAATTTCAGACGCAGCTCTTAATGATAAATTTTCATATGTGGAATGT
CTTGGAAGCCGAATAGCAAGACAAGCAGTTGCTGACTACAGTCAACATATGGGAAAGATC
ACAGCTGACGATATAATTTTAACAACTGGTTGTTCTATGGCTGTTGAAGTTGCAATTCGT
TCATTAGCAAATCCTGATGAAAATGTTTTAGTTCCGCGTCCTTCATGGAATTATTCGACC
TGGATCCACGGTTCGGGAATTTTAGCGAAATATTACAATTTAAATCCAGAAAAAGAATGG
GAAATTGATTTGGAAGATTTGCAAAATAAAATCGATAAAAAAACTAAAGCTATAATAGTT
AATAGCCCGGGCAACCCTTGTGGAAACGTTTTTAGCAAAAATCATATTCTTGATATTATT
GAAATTGCTGAAAAAAATTGTTTGCCTATAATTTCTGATGAAATTTATGAATTCTTCACA
ATTCCAAGTGTTAAATTTTACTCATTTGCGACACTTTCAAAAACTGTTCCAGTTTTGGTT
TGTTCGGGATTAACAAAAAGGTTTTTGACTCCTGGTATTCGTTTGGATTGGGTAATTGTG
AATGATAGAGGAGATAAACTAAAGGAAATAAGAAAAGGCTTTCAAAATATTGCTGGAAGA
AATTTTTATCCAAATAGCACTGTGCAACATGCATTACCGAAAATTTTGAGTGAAGTCCCA
CAATCATTTTTTGATAAGAATAATCAAATGATTCATAATAATGCAAAAATTGTCTACGAT
CGATTGAAAAATGTTCCAGGACTTAATCCGATCATGTCAAAAGGAGCAATTTATATGTTG
ATTGGCATAAAACTTGAAAAATTTCCTAATATCAACTCGAGTCTTGAGTTCATGCAACGT
TTAGCAAACGAACAAAGTGTTTTTACATTTCCCTCTGAAGTCTTTAATTTTCCAGGATTT
TTGCGTTTTGTACTGACTTCTCACGATGAAGCTTTGGTTGAAGCATGTGAACGTCTTTCT
AAATTTTGTGAGAAATATTATAAAGATAAAACTTATGAGACTCTTTAA
>g14131.t1 Gene=g14131 Length=415
MAASKIIKKWNILPTEFSKNSINPLRLLWETQQPKGNPKLKEIHLQPGDPTLYGNFPPHP
IIAKAISDAALNDKFSYVECLGSRIARQAVADYSQHMGKITADDIILTTGCSMAVEVAIR
SLANPDENVLVPRPSWNYSTWIHGSGILAKYYNLNPEKEWEIDLEDLQNKIDKKTKAIIV
NSPGNPCGNVFSKNHILDIIEIAEKNCLPIISDEIYEFFTIPSVKFYSFATLSKTVPVLV
CSGLTKRFLTPGIRLDWVIVNDRGDKLKEIRKGFQNIAGRNFYPNSTVQHALPKILSEVP
QSFFDKNNQMIHNNAKIVYDRLKNVPGLNPIMSKGAIYMLIGIKLEKFPNINSSLEFMQR
LANEQSVFTFPSEVFNFPGFLRFVLTSHDEALVEACERLSKFCEKYYKDKTYETL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g14131.t1 | CDD | cd00609 | AAT_like | 43 | 401 | 2.25195E-70 |
| 7 | g14131.t1 | Coils | Coil | Coil | 157 | 177 | - |
| 5 | g14131.t1 | Gene3D | G3DSA:3.90.1150.10 | Aspartate Aminotransferase | 44 | 403 | 3.6E-110 |
| 6 | g14131.t1 | Gene3D | G3DSA:3.40.640.10 | - | 60 | 299 | 3.6E-110 |
| 2 | g14131.t1 | PANTHER | PTHR45744 | TYROSINE AMINOTRANSFERASE | 15 | 409 | 1.6E-122 |
| 3 | g14131.t1 | PANTHER | PTHR45744:SF2 | TYROSINE AMINOTRANSFERASE | 15 | 409 | 1.6E-122 |
| 8 | g14131.t1 | PIRSF | PIRSF000517 | Tyr_transaminase | 1 | 415 | 7.8E-128 |
| 1 | g14131.t1 | Pfam | PF00155 | Aminotransferase class I and II | 43 | 399 | 5.9E-58 |
| 4 | g14131.t1 | SUPERFAMILY | SSF53383 | PLP-dependent transferases | 36 | 407 | 3.68E-74 |
| 10 | g14131.t1 | TIGRFAM | TIGR01265 | tyr_nico_aTase: tyrosine/nicotianamine family aminotransferase | 10 | 406 | 2.4E-126 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0009058 | biosynthetic process | BP |
| GO:0006520 | cellular amino acid metabolic process | BP |
| GO:0008483 | transaminase activity | MF |
| GO:0003824 | catalytic activity | MF |
| GO:0030170 | pyridoxal phosphate binding | MF |
KEGG
Orthology
- This transcript has been annotated with K00812 (aspartate aminotransferase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
