General information for g14219.t13
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Alanine aminotransferase 2.
Parent gene
- The parent gene g14219 is located on chr_1: 35491970..35501657 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g14219 | g14219.t13 | TSS | g14219.t13 | 35491029 | 35491029 |
| chr_1 | g14219 | g14219.t13 | isoform | g14219.t13 | 35491812 | 35494445 |
| chr_1 | g14219 | g14219.t13 | exon | g14219.t13.exon1 | 35491812 | 35492043 |
| chr_1 | g14219 | g14219.t13 | cds | g14219.t13.CDS1 | 35491970 | 35492043 |
| chr_1 | g14219 | g14219.t13 | exon | g14219.t13.exon2 | 35492103 | 35492151 |
| chr_1 | g14219 | g14219.t13 | cds | g14219.t13.CDS2 | 35492103 | 35492151 |
| chr_1 | g14219 | g14219.t13 | exon | g14219.t13.exon3 | 35492609 | 35492668 |
| chr_1 | g14219 | g14219.t13 | cds | g14219.t13.CDS3 | 35492609 | 35492668 |
| chr_1 | g14219 | g14219.t13 | exon | g14219.t13.exon4 | 35492737 | 35492766 |
| chr_1 | g14219 | g14219.t13 | cds | g14219.t13.CDS4 | 35492737 | 35492766 |
| chr_1 | g14219 | g14219.t13 | exon | g14219.t13.exon5 | 35493918 | 35494047 |
| chr_1 | g14219 | g14219.t13 | cds | g14219.t13.CDS5 | 35493918 | 35494047 |
| chr_1 | g14219 | g14219.t13 | exon | g14219.t13.exon6 | 35494107 | 35494445 |
| chr_1 | g14219 | g14219.t13 | cds | g14219.t13.CDS6 | 35494107 | 35494444 |
| chr_1 | g14219 | g14219.t13 | TTS | g14219.t13 | NA | NA |
Sequences
>g14219.t13 Gene=g14219 Length=840
AGAGCTGTTTAACTATGGCAACCCTCACTTCATTCATTTCTCATTCACTTCGTTCAACAA
AACATTTTAGTCGTATTATACACCGGTCGTCGTATAAGTCCGTTTTAAGCTATCATCTAA
ATAATTCTGAAAATTTTTGGTCATCATCACCAAGAGAAATGTCGACTTTAGGAAAATGTC
TTTCTATTGATAACATCAATCCATGCATAAAAACTATGGAATATGCTGTGAGAGGACCTC
TCGTAATTCGTGCGGCAGCTATTGAAAAAGAATTGGAGCAGGGCGTTAAGAAGCCATTTA
ATGAAGTCATACGAGCAAATATTGGCGATTGCCATGCTATGGGTCAAATTCCCATTACTT
TTATTCGTCAAGTACTTGGTCTGTGCGTTTATGAGAAACTTTTTGATGATCCAACAATTC
CCTCGGATGCTAAACAACGTGCACGCGACATCTTGAATGGTTGCAAAGGTGGCTCATTGG
GCTCTTATTCAGACTCGACTGGTATCGAAGTCATAAGAAGACATTGTGCTGAGTACATTC
ATAAACGTGATGGAATCCCATCGAATGCTGACGACATTATTTTGTCAGCTGGTGCTTCTG
GCAGCATTAAAGCAATTCTTGCACTTCTTCGCTGTGATATTGATGGAAAAAGACCAGGTG
TAATGGTACCTATTCCACAATATCCATTATATTCTGCTACAATCGCAGAATTTGACATGC
AACAAATTGGATATTACTTAGATGAATCAAACAATTGGGGATTAGATATTGCTGAATTGC
AAAGATCGATTGATGAGGCAAAGAAAAATTCATATCCACGTGCAATTGTTATTATTAATC
>g14219.t13 Gene=g14219 Length=227
MSTLGKCLSIDNINPCIKTMEYAVRGPLVIRAAAIEKELEQGVKKPFNEVIRANIGDCHA
MGQIPITFIRQVLGLCVYEKLFDDPTIPSDAKQRARDILNGCKGGSLGSYSDSTGIEVIR
RHCAEYIHKRDGIPSNADDIILSAGASGSIKAILALLRCDIDGKRPGVMVPIPQYPLYSA
TIAEFDMQQIGYYLDESNNWGLDIAELQRSIDEAKKNSYPRAIVIIN
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 5 | g14219.t13 | Gene3D | G3DSA:3.90.1150.10 | Aspartate Aminotransferase | 3 | 79 | 0 |
| 6 | g14219.t13 | Gene3D | G3DSA:3.40.640.10 | - | 108 | 227 | 0 |
| 2 | g14219.t13 | PANTHER | PTHR11751 | ALANINE AMINOTRANSFERASE | 5 | 227 | 0 |
| 3 | g14219.t13 | PANTHER | PTHR11751:SF308 | ALANINE AMINOTRANSFERASE 1 | 5 | 227 | 0 |
| 1 | g14219.t13 | Pfam | PF00155 | Aminotransferase class I and II | 71 | 227 | 0 |
| 4 | g14219.t13 | SUPERFAMILY | SSF53383 | PLP-dependent transferases | 46 | 227 | 0 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0009058 | biosynthetic process | BP |
| GO:0003824 | catalytic activity | MF |
| GO:0030170 | pyridoxal phosphate binding | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
