General information for g14284.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial.
Parent gene
- The parent gene g14284 is located on chr_1: 36304645..36305722 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g14284 | g14284.t1 | isoform | g14284.t1 | 36304352 | 36305722 |
| chr_1 | g14284 | g14284.t1 | exon | g14284.t1.exon1 | 36304352 | 36305001 |
| chr_1 | g14284 | g14284.t1 | cds | g14284.t1.CDS1 | 36304352 | 36305001 |
| chr_1 | g14284 | g14284.t1 | exon | g14284.t1.exon2 | 36305050 | 36305112 |
| chr_1 | g14284 | g14284.t1 | cds | g14284.t1.CDS2 | 36305050 | 36305112 |
| chr_1 | g14284 | g14284.t1 | exon | g14284.t1.exon3 | 36305168 | 36305415 |
| chr_1 | g14284 | g14284.t1 | cds | g14284.t1.CDS3 | 36305168 | 36305415 |
| chr_1 | g14284 | g14284.t1 | exon | g14284.t1.exon4 | 36305487 | 36305662 |
| chr_1 | g14284 | g14284.t1 | cds | g14284.t1.CDS4 | 36305487 | 36305662 |
| chr_1 | g14284 | g14284.t1 | exon | g14284.t1.exon5 | 36305720 | 36305722 |
| chr_1 | g14284 | g14284.t1 | cds | g14284.t1.CDS5 | 36305720 | 36305722 |
| chr_1 | g14284 | g14284.t1 | TSS | g14284.t1 | NA | NA |
| chr_1 | g14284 | g14284.t1 | TTS | g14284.t1 | NA | NA |
Sequences
>g14284.t1 Gene=g14284 Length=1140
ATGATTCGAACATCTAAGTTTATTGTAGGCCTCAAGCCGCATAAACTAGCAGTAATTGGT
AATTTTACAAGAAGCATGTCATCATCGAGTGATGTACTTGTGACTGAGCGAGGAAATGCA
GGAATAATTACTATAAATCGGCCAAAAACATTGAATGCAATCAATACTGATATGGTCAAA
ACAATTTATGCAGCAATGAAAGATTTTGCATCAAAAGATGATAAGCATTTGGTGATAATT
AAGGGAGCTGGAGAAAAGTCATTTTGCGCTGGTGGTGACGTAAGAGCTGTAGTTGAAAAT
GATGTTTCATTTGGAAAAGATTTCTTTAGAAATGAATACAAGAATAATGAATTGATAGGA
AATTACAAAAAACCATATATTGCAATTATTGATGGCATCACAATGGGCGGTGGTGTTGGT
CTAAGCGTACATGGAAAATATCGAGTTGCAACAGAAAGGACATTGTTCGCGATGCCTGAA
ACAGCAATTGGTCTTTTTCCTGATGTTGGTGGCGGTTATTTTTTGCCACGAATGAATGGA
AACCTCGGTATATATCTCGGGCTGACTGGATTTAGACTGAAAGGTCGTGATGTACAAAAA
GCAGGTGTGGCTACTCATTTCATTGAAAGCTCTGCACTTGAAGACTTAGAAAATCAGCTT
ACAAAATGCAAGAATTTTGATGATATTGATAAAACATTGGAAAAACTTCAGTCTCAGTTT
AAAGATACCACAGACTTTGTATTACAGCCTCATTTAAAACAAATTGAAAAGGCTTTTGGT
GGTGATACGATGGAGCAAATTTTGAAAAATCTTCACTCTGATGGCTCTGAGTGGGCAATG
TCAACACTTAAATTAATTAGCAAAATGAGTCCAACGAGCCTTAAAGTAACTCTTCGTCAA
CTTCAACTTGGCAAATCAATGTCTTTGCGTGAGTGCCTTCAAATGGAATTTCGCTTAGCT
GTTCATTGCTGCATCGAGAGCGATTTTAAAGAAGGTGTTCGGGCATTACTTATTGATAAA
GATCAACAACCAAAATGGAATCCCAGTAAAATCGAAGACGTGACACAAGGTCATGTTTTA
AAATTTTTTGTCCCTCTTCCCGATAACGACGAATTGGTTTTTGATCATTCAAAATTGTAA
>g14284.t1 Gene=g14284 Length=379
MIRTSKFIVGLKPHKLAVIGNFTRSMSSSSDVLVTERGNAGIITINRPKTLNAINTDMVK
TIYAAMKDFASKDDKHLVIIKGAGEKSFCAGGDVRAVVENDVSFGKDFFRNEYKNNELIG
NYKKPYIAIIDGITMGGGVGLSVHGKYRVATERTLFAMPETAIGLFPDVGGGYFLPRMNG
NLGIYLGLTGFRLKGRDVQKAGVATHFIESSALEDLENQLTKCKNFDDIDKTLEKLQSQF
KDTTDFVLQPHLKQIEKAFGGDTMEQILKNLHSDGSEWAMSTLKLISKMSPTSLKVTLRQ
LQLGKSMSLRECLQMEFRLAVHCCIESDFKEGVRALLIDKDQQPKWNPSKIEDVTQGHVL
KFFVPLPDNDELVFDHSKL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 6 | g14284.t1 | CDD | cd06558 | crotonase-like | 32 | 220 | 0 |
| 5 | g14284.t1 | Gene3D | G3DSA:3.90.226.40 | - | 26 | 378 | 0 |
| 2 | g14284.t1 | PANTHER | PTHR43176 | 3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED | 31 | 369 | 0 |
| 3 | g14284.t1 | PANTHER | PTHR43176:SF3 | 3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL | 31 | 369 | 0 |
| 1 | g14284.t1 | Pfam | PF16113 | Enoyl-CoA hydratase/isomerase | 41 | 363 | 0 |
| 4 | g14284.t1 | SUPERFAMILY | SSF52096 | ClpP/crotonase | 28 | 346 | 0 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0003860 | 3-hydroxyisobutyryl-CoA hydrolase activity | MF |
KEGG
Orthology
- This transcript has been annotated with K05605 (3-hydroxyisobutyryl-CoA hydrolase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
