General information for g14284.t12
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial.
Parent gene
- The parent gene g14284 is located on chr_1: 36304645..36305722 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g14284 | g14284.t12 | isoform | g14284.t12 | 36304352 | 36305722 |
| chr_1 | g14284 | g14284.t12 | exon | g14284.t12.exon1 | 36304352 | 36305001 |
| chr_1 | g14284 | g14284.t12 | cds | g14284.t12.CDS1 | 36304352 | 36305001 |
| chr_1 | g14284 | g14284.t12 | exon | g14284.t12.exon2 | 36305050 | 36305112 |
| chr_1 | g14284 | g14284.t12 | cds | g14284.t12.CDS2 | 36305050 | 36305068 |
| chr_1 | g14284 | g14284.t12 | exon | g14284.t12.exon3 | 36305164 | 36305722 |
| chr_1 | g14284 | g14284.t12 | TSS | g14284.t12 | NA | NA |
| chr_1 | g14284 | g14284.t12 | TTS | g14284.t12 | NA | NA |
Sequences
>g14284.t12 Gene=g14284 Length=1272
ATGGTAATTTTAATTAATTATTCCATAAATCAGCATAATTTTAATCAAAATACTATATAG
ATTCGAACATCTAAGTTTATTGTAGGCCTCAAGCCGCATAAACTAGCAGTAATTGGTAAT
TTTACAAGAAGCATGTCATCATCGAGTGATGTACTTGTGACTGAGCGAGGAAATGCAGGA
ATAATTACTATAAATCGGCCAAAAACATTGAATGCAATCAATACTGATATGGTCAAGTGT
GTAGATTTTCTAAAAATATCTTTATCAACTCTATTACGATATTAAAATTATAATTTATTA
TTTAAAGAACAATTTATGCAGCAATGAAAGATTTTGCATCAAAAGATGATAAGCATTTGG
TGATAATTAAGGGAGCTGGAGAAAAGTCATTTTGCGCTGGTGGTGACGTAAGAGCTGTAG
TTGAAAATGATGTTTCATTTGGAAAAGATTTCTTTAGAAATGAATACAAGAATAATGAAT
TGATAGGAAATTACAAAAAACCATATATTGCAATTATTGATGGCATCACAATGGGCGGTG
GTGTTGGTCTAAGCGGTATTACATGGAAAATATCGAGTTGCAACAGAAAGGACATTGTTC
GCGATGCCTGAAACAGCAATTGGTCTTTTTCCTGATGTTGGTGGCGGTTATTTTTTGCCA
CGAATGAATGGAAACCTCGGTATATATCTCGGGCTGACTGGATTTAGACTGAAAGGTCGT
GATGTACAAAAAGCAGGTGTGGCTACTCATTTCATTGAAAGCTCTGCACTTGAAGACTTA
GAAAATCAGCTTACAAAATGCAAGAATTTTGATGATATTGATAAAACATTGGAAAAACTT
CAGTCTCAGTTTAAAGATACCACAGACTTTGTATTACAGCCTCATTTAAAACAAATTGAA
AAGGCTTTTGGTGGTGATACGATGGAGCAAATTTTGAAAAATCTTCACTCTGATGGCTCT
GAGTGGGCAATGTCAACACTTAAATTAATTAGCAAAATGAGTCCAACGAGCCTTAAAGTA
ACTCTTCGTCAACTTCAACTTGGCAAATCAATGTCTTTGCGTGAGTGCCTTCAAATGGAA
TTTCGCTTAGCTGTTCATTGCTGCATCGAGAGCGATTTTAAAGAAGGTGTTCGGGCATTA
CTTATTGATAAAGATCAACAACCAAAATGGAATCCCAGTAAAATCGAAGACGTGACACAA
GGTCATGTTTTAAAATTTTTTGTCCCTCTTCCCGATAACGACGAATTGGTTTTTGATCAT
TCAAAATTGTAA
>g14284.t12 Gene=g14284 Length=222
MPETAIGLFPDVGGGYFLPRMNGNLGIYLGLTGFRLKGRDVQKAGVATHFIESSALEDLE
NQLTKCKNFDDIDKTLEKLQSQFKDTTDFVLQPHLKQIEKAFGGDTMEQILKNLHSDGSE
WAMSTLKLISKMSPTSLKVTLRQLQLGKSMSLRECLQMEFRLAVHCCIESDFKEGVRALL
IDKDQQPKWNPSKIEDVTQGHVLKFFVPLPDNDELVFDHSKL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 5 | g14284.t12 | Gene3D | G3DSA:3.90.226.40 | - | 1 | 221 | 0 |
| 2 | g14284.t12 | PANTHER | PTHR43176 | 3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED | 1 | 212 | 0 |
| 3 | g14284.t12 | PANTHER | PTHR43176:SF3 | 3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL | 1 | 212 | 0 |
| 1 | g14284.t12 | Pfam | PF16113 | Enoyl-CoA hydratase/isomerase | 1 | 206 | 0 |
| 4 | g14284.t12 | SUPERFAMILY | SSF52096 | ClpP/crotonase | 1 | 189 | 0 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0003860 | 3-hydroxyisobutyryl-CoA hydrolase activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
