General information for g14384.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Calcium-activated chloride channel regulator 2.
Parent gene
- The parent gene g14384 is located on chr_4: 198141..199420 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g14384 | g14384.t1 | isoform | g14384.t1 | 178298 | 199420 |
| chr_4 | g14384 | g14384.t1 | exon | g14384.t1.exon1 | 178298 | 178450 |
| chr_4 | g14384 | g14384.t1 | cds | g14384.t1.CDS1 | 178298 | 178450 |
| chr_4 | g14384 | g14384.t1 | exon | g14384.t1.exon2 | 196229 | 198077 |
| chr_4 | g14384 | g14384.t1 | cds | g14384.t1.CDS2 | 196229 | 198077 |
| chr_4 | g14384 | g14384.t1 | exon | g14384.t1.exon3 | 198141 | 199420 |
| chr_4 | g14384 | g14384.t1 | cds | g14384.t1.CDS3 | 198141 | 199420 |
| chr_4 | g14384 | g14384.t1 | TSS | g14384.t1 | NA | NA |
| chr_4 | g14384 | g14384.t1 | TTS | g14384.t1 | NA | NA |
Sequences
>g14384.t1 Gene=g14384 Length=3282
ATGTCAAATAGCATAAAATTTGTGTGCCTGATGCTGTGCATCGGGCTTACTCGCTCAATT
ATTGTACGAAATGGTGTATATGAGAATTTTGTGATTGAAATTCAAAAGGACGTAAGCGAT
GACGATTGTAATAAATTTTTATTAACACTTGAGAAAATATTGTCATCGTCTTCACAATAT
CTTCACTCAACTCTTGATAACAGAATTTTATTCAATTCAATAGATATTATTTTACCTCCA
GCTTGGTCAAATAATTGTGTAACAAATACAACTGTAACTAGTTACAATGGTGCTTCAACT
GACGCACAAATTATAACGACACATTCAATCTTTGGTGACGATTTATGGACAAAACAAGCA
AGTAGTTGTGGCGAGCATGGTGAACAGATTTATATGAGTGAACGTTCAATTCGCGAAAGC
TATGAAAATGTTGAAAAGAAATTTGTTACAGAATTTATGAAATATCGCTATGGTGTGTTT
GACACAAATGGATTTGATAGTGATCCAATATATCCAAAATGTAGTGCAAGCAATAATCCA
ATTTGCAATGATGCTATGAGTCTTGAATCATCAGCTTCATATAATCGATATATGCCGACG
AAACAAAATCAACTTTGTAATAGAATGAGTCGTATGGATGTGGTTATGGGAAATTCAGAT
TTTAATAGCAGTTTTAATGGACAGAGAACTGTTGAGTATATGCCACCAACTTTCAATTAT
GTACGCAAAATGAGTACTCGATATATGGTTGTAGTTGATGATCATGCTGATATTTCCATT
CGTGATAGTTATTCATTTCTACGTGATGCTATTCGTAAATGGCTTGATAAGGATTTAACG
CATCATGGCACTGAAGTCGGAATAACTAAAATCAGTTCAAATGAAGGAAGCACAATTAGA
ACAATCACATCAAGTCACGATTCTGATGAATTATTTGCAAAACTTCCATTTATCGTTAGT
AATCGAGCAGGTCTCGGTAAATGCAATATTGAAAGTTCTATTGATCGTTCAATTGAGCTC
ATGCGAGATCGTGTAAAAGTACATGGTGATGCCATTAGTGCAATAATTTTGATAGCTCCT
GGAATGTACAATTGCAGTCAAGAAGTACTGGATGGGATTATAAATAGAGCAAATGCCGCT
TATATTAAAATTGTGACCATTAATTATCCGAAAATTGGAACTAATCGTGTTCCATTAGAT
GAGTTAGCGATTCGCACTGGTGGACAAGCTTTTACAGTTGTCGAACGCAAGAGTAATGAA
GATCGTAGTTTATTATCAACATTTTTTGAGTTAACAAGTGTATTTATGCAAATTAGTGCA
GCATATCATCATGGTGATCAAGCTGATTTGCCAATTGAAATTTATCGTAAAGAACTGCAT
GATGCCAATATCTCAGGTGATTCAACCAAGGCTCGCACATATACAGATAGTTTTAATGTT
GATGATGCCACCAGAAATATTCATTTTTATTTGTACTTTTATGATCGAAAAGATATTGGA
ATGTTCATTGATGGGATGAGTTTAACTTCGCCTAATCAGCAGACATTTACTGCATATACT
GAACTCAGATCTGACTATCATCAATTGACTTTTGTAAGTAATCTCAGTGGAGCTGGATCA
TGGCATTATAATGTTAAACGTTTTAATGGACCACAACCTCATTTTGTACAAGTTCTTGCT
TATCCTAAAATTGATACAACAAGTTTTATTAAAGCAAGAGCATGGATTCATAAGCCAAAT
AATGGTGGACCAAATAAAATTTATGTTGAAGTCATGCAGGGTAATCTTCCAATTGTTGAT
GCACTTGTGGAAATTAATGTGAAATTACCAAATGGAAGAGAAGAGAAAATGCAATTATTT
GACAGTGGAAGTGGAGATCCCGATGTGACAAGAGGTGATGGAATTTACTCTAGATATTTC
ATGGCTGAAGATATTGGAATGCATCAATTTGCAATTAAAATCAGTGATAATGGAAATACA
GCTTATATTCAAATAGATAGAGATCCATTAAAACAAATTCATTGTTGTGGAAGTGCAATA
ATTACTCCCTCAAAACAACCAGTAACACCTTTCACACGTCACATTGCACCATTAACAATT
TTCATCACTCAAGATGATCTTGATAATGCGAGAGAAAAATTATCTTCAATTGGTCGTATT
GGTGATCTTCATGTAACAGCAACAAATGGAAGTGAAAAAGTAATTCTTGAATGGACTGGA
CCAGATACTGGTTTAGAAAATAGCAAAGCTGAATTTGAAATTCGTTATGCACTATCACTT
AAAGATATTGTTGATTCATTTGACAATATTGCTATGCCATGGCCACTTGCAGAAACTATT
CCTCATTCAATTGGTCAAGGAGCTTCTGTAACTCTCAATCTACTCAATGAACCTACACTC
ATTGGTGTACCTTTTTATGTTGCAATTCGTTCAGCAAACACAATTTCAAATTATGCAAGA
ATTTTTGTACCAAAACGAAAGCCTACAGCATCACCAACTTATACTCATATTGATAACGAT
ATTTACGAGACTGATCCATCAATGGAACCAGCTGATGAGGACGATGGAATTTTCAAACAT
CATAATTTAGCTTCAATCCCTTGGTCAATTATCATTCCAATAATTGTGTGCTGTCTTTTC
ATTCTTTTGGCTTTCATAATTTATTTCTGTTGTTGTCGAAGAAATTATAAACAACCGACT
AAATCACCTGCAAAACCAGCAATTTCTGTTATCACACCAAGCACTCCTGTTCAACAAAAT
CAATATCATGTTGAACCAGGCTATCTTGTTGACGTTCCAGATCATCATACTGTAGGATTG
CCAATGATTGACGATGAATTAATGAAGCCAGATTTTACTGATCATGATAAAATGTTGATT
GAAGAAATGAAACAACAGCAACGTTTTCAACAAGCTTTTGATCAGCAGCAACAAATTATT
ACATCAACATTGACAAGAAATGGTCAATATCTTTCACCATATGAAAGTTGGTCAGCATCA
ACTCTTCTGAATGAACATGAAGTGCGACAATCACCTTTAGATATGTATGTCGATGCAAAT
GGAGACATTGTGCCACAAATACCTCCCCATCCTTATCATCAACAACAAAACACTGCATAT
GGATATGTAGATCCAAATAGAGCACCTCCGCCTCAATACAGCAGCGTTTATCGACCATTA
GTAAGAGGTGTACCTGGTCAAGGATCAATGCAATCTGTAGTTAGTAGTGCGATGATGAGT
AATAGTGATGGAAAGAAAATACGAAATGTAACGATGGTGTAA
>g14384.t1 Gene=g14384 Length=1093
MSNSIKFVCLMLCIGLTRSIIVRNGVYENFVIEIQKDVSDDDCNKFLLTLEKILSSSSQY
LHSTLDNRILFNSIDIILPPAWSNNCVTNTTVTSYNGASTDAQIITTHSIFGDDLWTKQA
SSCGEHGEQIYMSERSIRESYENVEKKFVTEFMKYRYGVFDTNGFDSDPIYPKCSASNNP
ICNDAMSLESSASYNRYMPTKQNQLCNRMSRMDVVMGNSDFNSSFNGQRTVEYMPPTFNY
VRKMSTRYMVVVDDHADISIRDSYSFLRDAIRKWLDKDLTHHGTEVGITKISSNEGSTIR
TITSSHDSDELFAKLPFIVSNRAGLGKCNIESSIDRSIELMRDRVKVHGDAISAIILIAP
GMYNCSQEVLDGIINRANAAYIKIVTINYPKIGTNRVPLDELAIRTGGQAFTVVERKSNE
DRSLLSTFFELTSVFMQISAAYHHGDQADLPIEIYRKELHDANISGDSTKARTYTDSFNV
DDATRNIHFYLYFYDRKDIGMFIDGMSLTSPNQQTFTAYTELRSDYHQLTFVSNLSGAGS
WHYNVKRFNGPQPHFVQVLAYPKIDTTSFIKARAWIHKPNNGGPNKIYVEVMQGNLPIVD
ALVEINVKLPNGREEKMQLFDSGSGDPDVTRGDGIYSRYFMAEDIGMHQFAIKISDNGNT
AYIQIDRDPLKQIHCCGSAIITPSKQPVTPFTRHIAPLTIFITQDDLDNAREKLSSIGRI
GDLHVTATNGSEKVILEWTGPDTGLENSKAEFEIRYALSLKDIVDSFDNIAMPWPLAETI
PHSIGQGASVTLNLLNEPTLIGVPFYVAIRSANTISNYARIFVPKRKPTASPTYTHIDND
IYETDPSMEPADEDDGIFKHHNLASIPWSIIIPIIVCCLFILLAFIIYFCCCRRNYKQPT
KSPAKPAISVITPSTPVQQNQYHVEPGYLVDVPDHHTVGLPMIDDELMKPDFTDHDKMLI
EEMKQQQRFQQAFDQQQQIITSTLTRNGQYLSPYESWSASTLLNEHEVRQSPLDMYVDAN
GDIVPQIPPHPYHQQQNTAYGYVDPNRAPPPQYSSVYRPLVRGVPGQGSMQSVVSSAMMS
NSDGKKIRNVTMV
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 8 | g14384.t1 | Gene3D | G3DSA:3.40.50.410 | - | 249 | 423 | 4.4E-6 |
| 2 | g14384.t1 | PANTHER | PTHR10579 | CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR | 9 | 176 | 1.0E-37 |
| 4 | g14384.t1 | PANTHER | PTHR10579:SF2 | CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR 4 | 9 | 176 | 1.0E-37 |
| 3 | g14384.t1 | PANTHER | PTHR10579 | CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR | 192 | 769 | 1.0E-37 |
| 5 | g14384.t1 | PANTHER | PTHR10579:SF2 | CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR 4 | 192 | 769 | 1.0E-37 |
| 1 | g14384.t1 | Pfam | PF08434 | Calcium-activated chloride channel N terminal | 22 | 171 | 1.1E-16 |
| 11 | g14384.t1 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 19 | - |
| 12 | g14384.t1 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 6 | - |
| 13 | g14384.t1 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 7 | 14 | - |
| 15 | g14384.t1 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 15 | 19 | - |
| 10 | g14384.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 20 | 867 | - |
| 14 | g14384.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 868 | 891 | - |
| 9 | g14384.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 892 | 1093 | - |
| 17 | g14384.t1 | ProSiteProfiles | PS50234 | VWFA domain profile. | 247 | 428 | 8.545 |
| 6 | g14384.t1 | SUPERFAMILY | SSF53300 | vWA-like | 264 | 416 | 4.82E-5 |
| 7 | g14384.t1 | SignalP_EUK | SignalP-noTM | SignalP-noTM | 1 | 19 | - |
| 16 | g14384.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 868 | 890 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
There are no GO annotations for this transcript.
KEGG
Orthology
- This transcript has been annotated with K05028 (calcium-activated chloride channel regulator 2)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
