General information for g14411.t10
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Cystathionine gamma-lyase.
Parent gene
- The parent gene g14411 is located on chr_4: 362015..362631 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g14411 | g14411.t10 | isoform | g14411.t10 | 361870 | 362631 |
| chr_4 | g14411 | g14411.t10 | exon | g14411.t10.exon1 | 361870 | 362631 |
| chr_4 | g14411 | g14411.t10 | cds | g14411.t10.CDS1 | 362056 | 362631 |
| chr_4 | g14411 | g14411.t10 | TTS | g14411.t10 | 362827 | 362827 |
| chr_4 | g14411 | g14411.t10 | TSS | g14411.t10 | NA | NA |
Sequences
>g14411.t10 Gene=g14411 Length=762
AAAATTTTATAAATAAGATTGAAATTTAAGTTTAAATTTATTTCAAATTTAAGGCCATTG
TTTTAGTTGATAATACATTCCTTTCACCATACTTTCAACGTCCAATTGACCTTGGTGCTG
ATGCTGTAACTTATTCATTAACAAAATATATGAATGGTAATAAAAGCTTAAACTTATAAA
TTAATAATGTTGACTTATTCATCAAATTCAGGCCATGCAGACGTTGTGATGGGGAGTATA
GCTACAAGTAATTCAAAACTATATGAAAGTCTCAAATTTTATCAAAATGCCACTGGAATT
GTACCTTCCCCTTTTGACTGTTATTTGGTTAATCGAAGTCTTAAAACTCTTGCACTTCGT
ATGGAACACCATTTTAAAACATCAGTAGCTATTGCAAAATATCTTGAAACTCATGATAGA
GTTGAAAGAGTTATGCATCCAGCACTGCCATCACATCCTCAATATGATATTACTTTGAAG
CAAACTTATGGTCATTCAGGCATTTTTTCTTTTTATTTACGCAATGGAAATCTCGAAAGT
TCAACGAAATTCTTGCAAGCTTTGAAAATTTTTATGATAGCAGAATCACTTGGTGGATTC
GAGAGTTTGGTTGAATTGCCCTCAGTTATGACACATGCAAGCGTTCCCGAAGAACAAAGA
GCTGAACTTGGAATTAATGATGGATTAATTAGAGTAAGTGTCGGATTGGAAAATGCAAAA
GATTTGATTGAAGATTTTGAAAATGCTTTTAAAGTAATTTAA
>g14411.t10 Gene=g14411 Length=191
MLTYSSNSGHADVVMGSIATSNSKLYESLKFYQNATGIVPSPFDCYLVNRSLKTLALRME
HHFKTSVAIAKYLETHDRVERVMHPALPSHPQYDITLKQTYGHSGIFSFYLRNGNLESST
KFLQALKIFMIAESLGGFESLVELPSVMTHASVPEEQRAELGINDGLIRVSVGLENAKDL
IEDFENAFKVI
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g14411.t10 | Coils | Coil | Coil | 174 | 191 | - |
| 6 | g14411.t10 | Gene3D | G3DSA:3.40.640.10 | - | 5 | 55 | 5.4E-12 |
| 5 | g14411.t10 | Gene3D | G3DSA:3.90.1150.10 | Aspartate Aminotransferase | 56 | 191 | 5.4E-50 |
| 2 | g14411.t10 | PANTHER | PTHR11808:SF15 | CYSTATHIONINE GAMMA-LYASE | 8 | 190 | 2.3E-64 |
| 3 | g14411.t10 | PANTHER | PTHR11808 | TRANS-SULFURATION ENZYME FAMILY MEMBER | 8 | 190 | 2.3E-64 |
| 1 | g14411.t10 | Pfam | PF01053 | Cys/Met metabolism PLP-dependent enzyme | 8 | 189 | 4.8E-65 |
| 4 | g14411.t10 | SUPERFAMILY | SSF53383 | PLP-dependent transferases | 4 | 189 | 7.63E-54 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0019346 | transsulfuration | BP |
| GO:0003824 | catalytic activity | MF |
| GO:0030170 | pyridoxal phosphate binding | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
