General information for g14433.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Eukaryotic translation initiation factor 4 gamma 3.
Parent gene
- The parent gene g14433 is located on chr_4: 499943..502207 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g14433 | g14433.t3 | TTS | g14433.t3 | 497690 | 497690 |
| chr_4 | g14433 | g14433.t3 | isoform | g14433.t3 | 497692 | 498612 |
| chr_4 | g14433 | g14433.t3 | exon | g14433.t3.exon1 | 497692 | 497930 |
| chr_4 | g14433 | g14433.t3 | cds | g14433.t3.CDS1 | 497694 | 497930 |
| chr_4 | g14433 | g14433.t3 | exon | g14433.t3.exon2 | 497993 | 498268 |
| chr_4 | g14433 | g14433.t3 | cds | g14433.t3.CDS2 | 497993 | 498268 |
| chr_4 | g14433 | g14433.t3 | exon | g14433.t3.exon3 | 498331 | 498612 |
| chr_4 | g14433 | g14433.t3 | cds | g14433.t3.CDS3 | 498331 | 498552 |
| chr_4 | g14433 | g14433.t3 | TSS | g14433.t3 | NA | NA |
Sequences
>g14433.t3 Gene=g14433 Length=797
AATTTAAGTGGCAAAAAATACTATACAAGAGATCAACTTTTAAAGCTTAAAGATGCAGTT
ATGGTGCCACCAATTCGTCTACCCGATGGTGTTGCAGGTCAATTGTCGAAGAACAACAAA
GAATATCTTACAAACACATTGACACAAGTGATGCCACCTATGGGTATGCGAACACCATAC
GATGCCATTAATAGTGTTGCACCCAAGTTTATGATGAACACTCCCGGTAATCGTAATCCT
TATCAAACTAAAAGACCTAGTCAACAAGGAAATCAACAAAAGGTGCCTGGTCGTGGTGGT
TCACAAACTGGTCCCGATCGTCAAATTTTGAAGATCAATTTGAGTCTACACGATGATGTT
AAGCTCAATGAATCAGAAAATGCATGGAAACCGACACATTTGAAAAAGAATGATAACTTA
AGCGAAGAAGAAAAAACAACAAATGAAACACTTAGTAAATTCCGTTCAATGCTCAATAAA
CTCACTGCGGAAAACTTTGGGGTTTTAGTTGAGCAGGTCCGGACATTTAAAATTGACACG
AGCGAGCGACTTGATGGGGTGATAAATTTACTATTTGAAAAGGCAATTTCAGAACCAAAA
TTTGCCCCAACTTATGCACAGTTATGTAATGAAATTGCCAACATTCAGACAGTGTCAACT
GGTACAGGTTTACAAGATCAAGTTCAAGATAAACAAGCAAAAAAAAATACATTAAAAGTT
CGACTGATTACACAATGTCAAAAAGAATTTGAAAGAAATAAAGAAGATACAATTAAATTT
AGAGAAATTGAAGAAAA
>g14433.t3 Gene=g14433 Length=245
MVPPIRLPDGVAGQLSKNNKEYLTNTLTQVMPPMGMRTPYDAINSVAPKFMMNTPGNRNP
YQTKRPSQQGNQQKVPGRGGSQTGPDRQILKINLSLHDDVKLNESENAWKPTHLKKNDNL
SEEEKTTNETLSKFRSMLNKLTAENFGVLVEQVRTFKIDTSERLDGVINLLFEKAISEPK
FAPTYAQLCNEIANIQTVSTGTGLQDQVQDKQAKKNTLKVRLITQCQKEFERNKEDTIKF
REIEE
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 8 | g14433.t3 | Gene3D | G3DSA:1.25.40.180 | - | 120 | 245 | 8.7E-29 |
| 6 | g14433.t3 | MobiDBLite | mobidb-lite | consensus disorder prediction | 61 | 86 | - |
| 7 | g14433.t3 | MobiDBLite | mobidb-lite | consensus disorder prediction | 61 | 79 | - |
| 5 | g14433.t3 | MobiDBLite | mobidb-lite | consensus disorder prediction | 107 | 127 | - |
| 2 | g14433.t3 | PANTHER | PTHR23253:SF63 | EUKARYOTIC TRANSLATION INITIATION FACTOR 4G1, ISOFORM B-RELATED | 45 | 241 | 3.5E-39 |
| 3 | g14433.t3 | PANTHER | PTHR23253 | EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA | 45 | 241 | 3.5E-39 |
| 1 | g14433.t3 | Pfam | PF02854 | MIF4G domain | 133 | 239 | 5.4E-20 |
| 4 | g14433.t3 | SUPERFAMILY | SSF48371 | ARM repeat | 127 | 240 | 2.19E-19 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0003723 | RNA binding | MF |
| GO:0005515 | protein binding | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
