General information for g14460.t2
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial.
Parent gene
- The parent gene g14460 is located on chr_4: 690083..690890 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g14460 | g14460.t2 | isoform | g14460.t2 | 687665 | 690890 |
| chr_4 | g14460 | g14460.t2 | exon | g14460.t2.exon1 | 687665 | 687813 |
| chr_4 | g14460 | g14460.t2 | TTS | g14460.t2 | 687670 | 687670 |
| chr_4 | g14460 | g14460.t2 | exon | g14460.t2.exon2 | 689194 | 689410 |
| chr_4 | g14460 | g14460.t2 | exon | g14460.t2.exon3 | 689521 | 690558 |
| chr_4 | g14460 | g14460.t2 | cds | g14460.t2.CDS1 | 689592 | 690558 |
| chr_4 | g14460 | g14460.t2 | exon | g14460.t2.exon4 | 690660 | 690785 |
| chr_4 | g14460 | g14460.t2 | cds | g14460.t2.CDS2 | 690660 | 690784 |
| chr_4 | g14460 | g14460.t2 | exon | g14460.t2.exon5 | 690884 | 690890 |
| chr_4 | g14460 | g14460.t2 | TSS | g14460.t2 | 690964 | 690964 |
Sequences
>g14460.t2 Gene=g14460 Length=1537
CCTTAAAAATGTTTTCAAAAATTTTAAATGCTTTCAAATCAAATCATGTAAATTTAAAAG
AGGTCAAAAACGCAGCAATTATAACATTCAATCGTCCACAAAAAATGAACACTTTTACAC
CAGAAATGCCAATATACTTATATCAGCTTTTTAAAGATTTAGAAAAGTCAGATAAATCAC
AGGTGATAATTCAAGGCTCTGGAAAGGCATTCTGTGCAGGTCTTGACCTCAAGGAAGCTC
TACAAATGAAATTTGATGAAATAAGCCGTCTTAATTTTTATACTTCAAACATCATGGATT
ACATTTCGCATTATAAAAAACCTTACATTGCCCTTATTGATGGAATTTGTATGGGTGGTG
CATGTTTCTTCTCTATGACTGCCAAATATAGGATTGCAACTGAACGCACAATTTTCGCCA
TGCCAGAGGCTGAAATTGGATTCTTTACTAATGCAGGTGCAAGTTATATCCTTCCAAGGC
TCAAATATAATCTTGGCTTTTATATTGCACTTGCTGGTGCACGACTTTATGGTTATGAAA
CTAAGAAATTTGGACTTGCATCGCATTTTGTTGAAAGCAAGCGAATGGATGAATTATTAA
AAGCTTTAGCTGAATGCAATGATGATTATCAAGTTTCGAAAACAATTGCTAAATTTTCAT
CTATTCCGAATGATTTACATTGTGATATAGATGAAATTTTATCATCAGTTGATAAATGCT
TTGATGGTGACTCAGTTGAGGAAATTGTTGATAATTTGCATCTTGATGGAAGTGAATGGG
CAATGCAAACTGTTAGAACTCTTAATAAAATGTCACCAACTAGTTTAAAAGTTTGTCATA
AACTTTTGACAAATGGAAAGAAATTAAATTTGCAAGAGTGTTTAAAACTTGAACATTTAT
TGATGACAAATATTATGAGAGAATTTAATCATGATTTTATTGAAGGTGTTCGAGCTTTGA
TTCTTGAAAAAGATTTAAAACCAAAATGGGAACCAAAAAAATTGCATGATGTTAAGGATG
ATTTATTGAGTAAAATATTTGCTCCTATTCCAAAGGATAAGGAACTTACTTTTGAAAGCA
ATGAAAAGGCTAAACTGTAGAAAAATTTGACAATAATTTTTAAATATTTCAACATAAAAT
ATGGCCATCTTTACAAATAATATAAAAATGATTCTATAAGAGTTTTTTGACAATATATAT
ATTTGATTCAAATAAACTAATGATATTTCTTTACATTTATAACTTCAGACTAAATTAACA
ACAGAAAAAAACACTGCACAAATTTAAATTAGTTAATTAAAATAGAATGTTCATTTTAGA
ACTTTCTTTCATCAACAGAGGAATGATATAAAATATGAAACTAGACTTTAGATCACATTT
TAAAAACAAAAATTTTCAATGTTTAAATGTTATCAAATTTATAAATTTTCTTAAACATCA
TGTCAATAATAGATGAAAAATTTATAATTCTTTAAAGTAAAAAATTTCAAGTAAAGAAAT
GGAATAAACAAAAATGTTACTTTAAGCAAATCAAAAA
>g14460.t2 Gene=g14460 Length=363
MFSKILNAFKSNHVNLKEVKNAAIITFNRPQKMNTFTPEMPIYLYQLFKDLEKSDKSQVI
IQGSGKAFCAGLDLKEALQMKFDEISRLNFYTSNIMDYISHYKKPYIALIDGICMGGACF
FSMTAKYRIATERTIFAMPEAEIGFFTNAGASYILPRLKYNLGFYIALAGARLYGYETKK
FGLASHFVESKRMDELLKALAECNDDYQVSKTIAKFSSIPNDLHCDIDEILSSVDKCFDG
DSVEEIVDNLHLDGSEWAMQTVRTLNKMSPTSLKVCHKLLTNGKKLNLQECLKLEHLLMT
NIMREFNHDFIEGVRALILEKDLKPKWEPKKLHDVKDDLLSKIFAPIPKDKELTFESNEK
AKL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 5 | g14460.t2 | CDD | cd06558 | crotonase-like | 14 | 202 | 0 |
| 4 | g14460.t2 | Gene3D | G3DSA:3.90.226.40 | - | 9 | 361 | 0 |
| 2 | g14460.t2 | PANTHER | PTHR43176 | 3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED | 20 | 352 | 0 |
| 1 | g14460.t2 | Pfam | PF16113 | Enoyl-CoA hydratase/isomerase | 23 | 344 | 0 |
| 3 | g14460.t2 | SUPERFAMILY | SSF52096 | ClpP/crotonase | 10 | 328 | 0 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0003860 | 3-hydroxyisobutyryl-CoA hydrolase activity | MF |
KEGG
Orthology
- This transcript has been annotated with K05605 (3-hydroxyisobutyryl-CoA hydrolase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
