General information for g145.t21
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative dTTP/UTP pyrophosphatase.
Parent gene
- The parent gene g145 is located on chr_3: 1335186..1336814 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g145 | g145.t21 | TTS | g145.t21 | 1335069 | 1335069 |
| chr_3 | g145 | g145.t21 | isoform | g145.t21 | 1335186 | 1336768 |
| chr_3 | g145 | g145.t21 | exon | g145.t21.exon1 | 1335186 | 1335728 |
| chr_3 | g145 | g145.t21 | cds | g145.t21.CDS1 | 1335186 | 1335728 |
| chr_3 | g145 | g145.t21 | exon | g145.t21.exon2 | 1335782 | 1335889 |
| chr_3 | g145 | g145.t21 | cds | g145.t21.CDS2 | 1335782 | 1335871 |
| chr_3 | g145 | g145.t21 | exon | g145.t21.exon3 | 1336725 | 1336768 |
| chr_3 | g145 | g145.t21 | TSS | g145.t21 | NA | NA |
Sequences
>g145.t21 Gene=g145 Length=695
GTAAAATTTTTAAACCATAGTCATACATAAAAATATTGAAAACAAAAATTAAGGACAAAA
TAATGTTGGCTCCTTTACAAGATCAATTAAAAAATGTACGCTTCATTCTTGCAAGTGGCA
GTCCTAGACGTCAGGAATATATTAAAAACTTGGGAATTGAAGCTGAATTATGTTCATCGG
AATTTGATGAGAGAACTATCAAGCCAAAAGATTACAAGTCATATGACGAATTTGTAATAG
CAATTGCAAATGGAAAAGCAGAAGAAGTTGAAAAAAGATTACAAAATGAATTAAAAGACA
CACAATATTGTATAATTGGAGCTGATACAATTAATGTATTGAATGATAAAATTTTCGGAA
AACCAAAGGATGAAGATGAAGCATTTCGAATGTTAAAAGAATTGAATGGTCAGCCACATT
TTGTGTACACTGGATGTGTGCTTAAATTTAACGATAAAGTTGTGAAATTTTGTGAGAGCA
CAAAAGTATTTTTTGGAAAATTAACAGAAGAGCAAATTAAGGCATACATTGACTCTAGAG
AACCTCTTGATAAATGTGGAGCTTATGGCACAGAAGATCTTGGTTCTTGTATGGTTGAAA
GAATTGAGGGAGATTATTTTGCAAATGTCGGGATTCCTCTCTATCGTATAAGTGTAGAAC
TCTGTAAAGCATTTAATTACGATACAAACAAATAA
>g145.t21 Gene=g145 Length=210
MLAPLQDQLKNVRFILASGSPRRQEYIKNLGIEAELCSSEFDERTIKPKDYKSYDEFVIA
IANGKAEEVEKRLQNELKDTQYCIIGADTINVLNDKIFGKPKDEDEAFRMLKELNGQPHF
VYTGCVLKFNDKVVKFCESTKVFFGKLTEEQIKAYIDSREPLDKCGAYGTEDLGSCMVER
IEGDYFANVGIPLYRISVELCKAFNYDTNK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g145.t21 | CDD | cd00555 | Maf | 14 | 200 | 1.20461E-75 |
| 7 | g145.t21 | Coils | Coil | Coil | 59 | 79 | - |
| 6 | g145.t21 | Gene3D | G3DSA:3.90.950.10 | - | 9 | 205 | 1.4E-59 |
| 4 | g145.t21 | Hamap | MF_00528 | dTTP/UTP pyrophosphatase. | 13 | 205 | 25.329342 |
| 2 | g145.t21 | PANTHER | PTHR43213 | BIFUNCTIONAL DTTP/UTP PYROPHOSPHATASE/METHYLTRANSFERASE PROTEIN-RELATED | 2 | 204 | 3.2E-54 |
| 3 | g145.t21 | PANTHER | PTHR43213:SF5 | BIFUNCTIONAL DTTP/UTP PYROPHOSPHATASE/METHYLTRANSFERASE PROTEIN-RELATED | 2 | 204 | 3.2E-54 |
| 8 | g145.t21 | PIRSF | PIRSF006305 | Maf | 5 | 209 | 2.4E-55 |
| 1 | g145.t21 | Pfam | PF02545 | Maf-like protein | 13 | 202 | 6.6E-53 |
| 5 | g145.t21 | SUPERFAMILY | SSF52972 | ITPase-like | 10 | 200 | 4.05E-52 |
| 10 | g145.t21 | TIGRFAM | TIGR00172 | maf: septum formation protein Maf | 13 | 196 | 2.1E-47 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0047429 | nucleoside-triphosphate diphosphatase activity | MF |
KEGG
Orthology
- This transcript has been annotated with K06287 (nucleoside triphosphate pyrophosphatase [EC:3.6.1.-])
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
