General information for g14575.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative NAD-dependent protein deacylase Sirt4.
Parent gene
- The parent gene g14575 is located on chr_4: 1387140..1388157 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g14575 | g14575.t3 | TTS | g14575.t3 | 1385841 | 1385841 |
| chr_4 | g14575 | g14575.t3 | isoform | g14575.t3 | 1386245 | 1386961 |
| chr_4 | g14575 | g14575.t3 | exon | g14575.t3.exon1 | 1386245 | 1386961 |
| chr_4 | g14575 | g14575.t3 | cds | g14575.t3.CDS1 | 1386246 | 1386548 |
| chr_4 | g14575 | g14575.t3 | TSS | g14575.t3 | 1387169 | 1387169 |
Sequences
>g14575.t3 Gene=g14575 Length=717
TTTGTTGTTTGATCCAGTTTGAGATTTTTCAAAAAATTCTTCCTGCTTATTTTGGGTTTT
TTAAATTTTTATTTCTCTAATTAGATTTTTTTGATAATCCTTTTTGTCTAAATTTAAATT
ATTTAAAAGAAATTCTTTTCTATTTTGAACGTCTTTTTTTATGAAACACCAATTCTTTTA
AAAATTATTTTTGTTTACATTTGAATTTCACTAAATAATTTACCTTTTTAGGCATTCCTG
ATTACCGATCAGAAGGTGTCGGTCTTTATCAACGTTCAAATCACAAACCTGTTCAGTATC
CAGAATTTATTCGATCACATGAAATAAGAAAACGCTATTGGGCAAGAAATTTCCTTGGTT
GGCCAAAATTCAGCAATGTTCAACCAAATTTGACTCATAAAAAACTTGCTGAAATGGAAA
AAGACAAAAAATTGCTTCACATTGTAACACAAAATGTTGACAATTTACATGCAAAAGCAG
GAAGCAAAGAATTCACAGAGCTTCATGGGAATGGCTACAAAGTAATCTGCGTTGGTCATG
AAGGAAAAGATCGCTGCGGTTATTCGATAGATCGTCATGATTTTCAAAAAATTTTAGAAT
CTTTCAATCAAGATTTGAAGGAAAAAGCTGAAATTATGAAATCTGAAAGTTTTCGACCTG
ACGGAGATGTTGAAATTTCATCGGATGATATTAAAAAATTTTATTTGCCGCAATGCC
>g14575.t3 Gene=g14575 Length=101
MEKDKKLLHIVTQNVDNLHAKAGSKEFTELHGNGYKVICVGHEGKDRCGYSIDRHDFQKI
LESFNQDLKEKAEIMKSESFRPDGDVEISSDDIKKFYLPQC
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 4 | g14575.t3 | Gene3D | G3DSA:3.40.50.1220 | - | 1 | 50 | 0.000 |
| 2 | g14575.t3 | PANTHER | PTHR43688 | NAD-DEPENDENT PROTEIN LIPOAMIDASE SIRTUIN-4 | 2 | 101 | 0.000 |
| 1 | g14575.t3 | Pfam | PF02146 | Sir2 family | 1 | 60 | 0.000 |
| 5 | g14575.t3 | ProSiteProfiles | PS50305 | Sirtuin catalytic domain profile. | 1 | 101 | 12.211 |
| 3 | g14575.t3 | SUPERFAMILY | SSF52467 | DHS-like NAD/FAD-binding domain | 2 | 95 | 0.000 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0070403 | NAD+ binding | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed