General information for g14652.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Serine protease inhibitor 42Dd.
Parent gene
- The parent gene g14652 is located on chr_4: 1754505..1755933 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g14652 | g14652.t1 | TSS | g14652.t1 | 1754502 | 1754502 |
| chr_4 | g14652 | g14652.t1 | isoform | g14652.t1 | 1754505 | 1755933 |
| chr_4 | g14652 | g14652.t1 | exon | g14652.t1.exon1 | 1754505 | 1754609 |
| chr_4 | g14652 | g14652.t1 | cds | g14652.t1.CDS1 | 1754505 | 1754609 |
| chr_4 | g14652 | g14652.t1 | exon | g14652.t1.exon2 | 1754664 | 1754880 |
| chr_4 | g14652 | g14652.t1 | cds | g14652.t1.CDS2 | 1754664 | 1754880 |
| chr_4 | g14652 | g14652.t1 | exon | g14652.t1.exon3 | 1754957 | 1755540 |
| chr_4 | g14652 | g14652.t1 | cds | g14652.t1.CDS3 | 1754957 | 1755540 |
| chr_4 | g14652 | g14652.t1 | exon | g14652.t1.exon4 | 1755600 | 1755744 |
| chr_4 | g14652 | g14652.t1 | cds | g14652.t1.CDS4 | 1755600 | 1755744 |
| chr_4 | g14652 | g14652.t1 | exon | g14652.t1.exon5 | 1755797 | 1755933 |
| chr_4 | g14652 | g14652.t1 | cds | g14652.t1.CDS5 | 1755797 | 1755933 |
| chr_4 | g14652 | g14652.t1 | TTS | g14652.t1 | NA | NA |
Sequences
>g14652.t1 Gene=g14652 Length=1188
ATGATATTATTGAAAATTTTTCTTATCTCTTATGTTGCATCCCAAAGTGATGCAAGTGAT
GATTTTTACAAACCTTTGTCAACTTTTGCTATTAAATTATTTCAAAAAGCAACAGATAAA
GTTTATGGAAATGTCATGATCTCACCAATGTCAATTGATTCAGCTTTAACAATGGCAATG
TATGGAGCAAATGGAGATACGAAAACATCATTATTTAATGGACTTTATTATTCAAGTTTT
GGAAGTTTGAGTTATGATACAGTTTTGAATAATTTTCAGCAAATGATGAAAAATTTGAAT
GGAAATCAAGCTTTGCAAATGGCTATAAAAATTTATGTAACCGATCAGTATAATTTGTCA
TTATATTTCAAATCAATTGCAACTGATTCATTTTTGTCTGAAATTGAAAGCATTAATTTT
GAAAAAAATGTTGATGCTGCGAATACTATAAATAATTGGGTTTCAAGCAAGACAAATCAA
AGAATACAAAATTTAATTGATCCATCTTCACTTATTAATGCAACAAGACTTGTTTTTATT
AACACAATTTTCTTTACTGCATTTTGGATTAAAAAGTTTCCAGCTGTTAATACAAAACCG
GACAAATTTTACACTGGTCCGAATTCATATGTCAAAGGTGATTTCATGAATATGATGGAT
TTTATTAATTTTGCTGATTTTCCCGAACTTAATGCGACTGCTGTTAAACTTGACTATAAA
AATTCTCCAATGACAATGATAATTTTATTGCCAAATTCAAGAACTGGTTTAGCTTATATG
AAATCACAACTTGATCAAATTGATTGGGCGAATATACAAAATAGATTTTCTTTGCAAACA
ACAGTATTGAAAATTCCCAAATTTAAATATTCTTACCAAATCGACGTCAAAACAACTTTG
AAAAAGATGGGACTGTCATTGATGTTTGAAGATAAAGCAGATTTCACAAACATGATCAAT
AATTATAATTGTATTTTAAAAATTGATAAAGTTTTACACAAAACTTTCATTTCTGTCCAT
GAAAATGGAACTGAAGCTGCTGCTGCTACAGGAATTGACTTCGCTGGTTCTGGTCCACCA
ACAAAACCAATCAATTTTATTGCTAACCATCCTTTTATTTTTATGCTTCAATATGCCGGG
AAAAGTGTTCATTTTATTGGACAAGTTTCTACTTTGATAAATATTTGA
>g14652.t1 Gene=g14652 Length=395
MILLKIFLISYVASQSDASDDFYKPLSTFAIKLFQKATDKVYGNVMISPMSIDSALTMAM
YGANGDTKTSLFNGLYYSSFGSLSYDTVLNNFQQMMKNLNGNQALQMAIKIYVTDQYNLS
LYFKSIATDSFLSEIESINFEKNVDAANTINNWVSSKTNQRIQNLIDPSSLINATRLVFI
NTIFFTAFWIKKFPAVNTKPDKFYTGPNSYVKGDFMNMMDFINFADFPELNATAVKLDYK
NSPMTMIILLPNSRTGLAYMKSQLDQIDWANIQNRFSLQTTVLKIPKFKYSYQIDVKTTL
KKMGLSLMFEDKADFTNMINNYNCILKIDKVLHKTFISVHENGTEAAAATGIDFAGSGPP
TKPINFIANHPFIFMLQYAGKSVHFIGQVSTLINI
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 12 | g14652.t1 | CDD | cd19601 | serpin42Da-like | 26 | 388 | 2.77578E-118 |
| 6 | g14652.t1 | Gene3D | G3DSA:3.30.497.10 | Antithrombin | 31 | 359 | 4.3E-96 |
| 5 | g14652.t1 | Gene3D | G3DSA:2.30.39.10 | - | 190 | 388 | 4.3E-96 |
| 2 | g14652.t1 | PANTHER | PTHR11461 | SERINE PROTEASE INHIBITOR, SERPIN | 26 | 389 | 2.8E-66 |
| 1 | g14652.t1 | Pfam | PF00079 | Serpin (serine protease inhibitor) | 27 | 390 | 1.5E-87 |
| 8 | g14652.t1 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 18 | - |
| 9 | g14652.t1 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 1 | - |
| 10 | g14652.t1 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 2 | 13 | - |
| 11 | g14652.t1 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 14 | 18 | - |
| 7 | g14652.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 19 | 395 | - |
| 13 | g14652.t1 | ProSitePatterns | PS00284 | Serpins signature. | 366 | 376 | - |
| 14 | g14652.t1 | SMART | SM00093 | serpin2 | 31 | 392 | 9.5E-73 |
| 3 | g14652.t1 | SUPERFAMILY | SSF56574 | Serpins | 18 | 390 | 3.01E-92 |
| 4 | g14652.t1 | SignalP_EUK | SignalP-noTM | SignalP-noTM | 1 | 18 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005615 | extracellular space | CC |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed