General information for g14660.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Poly [ADP-ribose] polymerase.
Parent gene
- The parent gene g14660 is located on chr_4: 1782873..1783573 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g14660 | g14660.t3 | TTS | g14660.t3 | 1782171 | 1782171 |
| chr_4 | g14660 | g14660.t3 | isoform | g14660.t3 | 1782192 | 1783573 |
| chr_4 | g14660 | g14660.t3 | exon | g14660.t3.exon1 | 1782192 | 1782408 |
| chr_4 | g14660 | g14660.t3 | exon | g14660.t3.exon2 | 1782856 | 1783371 |
| chr_4 | g14660 | g14660.t3 | cds | g14660.t3.CDS1 | 1782856 | 1783371 |
| chr_4 | g14660 | g14660.t3 | exon | g14660.t3.exon3 | 1783463 | 1783573 |
| chr_4 | g14660 | g14660.t3 | cds | g14660.t3.CDS2 | 1783463 | 1783573 |
| chr_4 | g14660 | g14660.t3 | TSS | g14660.t3 | 1783664 | 1783664 |
Sequences
>g14660.t3 Gene=g14660 Length=844
ATGGATGAACGTCCATATAAAACTGAATATGCAAAAAGTGGACGAGCAAAGTGTCGCAAA
TGCAGAAAAATTCTCAAAAAAGGAGAGTTAAGACTTGGTGTTTGGGTTGAGTCTAATTTT
TTTGATGGTAAAACATGTCAATGGTACCATTTGAGCTGTTTTTTCAAAAATCATCGCCCA
GGATCAATTCATGATATTGGACATTATGAAGAAATGAGCATTGAAGATCAAAAGAAAATT
CATGAGAAATTGGATGAAAATAAAGGACTTTTTTTGCCTGATACAAATGAAATTAAAAAA
GGCAAAAGACCTCATTCAATTGATGAAGAAGCAGCACCAAAAAATAAAGCTATAATTAAG
GATTTTGGTGTTGAATATGCAAAATCAGGTCGATCAACTTGTGTTGAATGTTTGAAAAAT
ATTGATGAGAATGAAATTCGTGTTAAAAAAATGGACTATTCGTCGGATATTGGGAAGAAA
TTTGGTGGTAAACCAATGTGGCATCATTTAGAATGTTTTGCTGCAAAACGTGAAGATTAC
AATTTTTATTTGGGTGGATCTCAATTACCTGGAATTTCTAAATTATTAAAAGGTGATCAA
AAAATTGTTGCTGATGTTATTCCGTAAGACAATTGATTTAAGCCCATCAGAAGTAAAAAA
AATAAAAGAAGATTTCGAAGAAAAGGAAGAAATTACTCTTGGTTGAATGAACAAAACTGA
ACATTCGTGACAATTTTTAACTTTCTTTTAAAATAATATTAAGTTCTCTTTTAAGAACAG
AAATTTTGAAATTTAATAATGTAAATGAATGAGTGTCATTGGATTGATTCTCAGTAATTA
GAAA
>g14660.t3 Gene=g14660 Length=208
MDERPYKTEYAKSGRAKCRKCRKILKKGELRLGVWVESNFFDGKTCQWYHLSCFFKNHRP
GSIHDIGHYEEMSIEDQKKIHEKLDENKGLFLPDTNEIKKGKRPHSIDEEAAPKNKAIIK
DFGVEYAKSGRSTCVECLKNIDENEIRVKKMDYSSDIGKKFGGKPMWHHLECFAAKREDY
NFYLGGSQLPGISKLLKGDQKIVADVIP
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g14660.t3 | Gene3D | G3DSA:3.30.1740.10 | - | 1 | 106 | 0.000 |
| 10 | g14660.t3 | Gene3D | G3DSA:3.30.1740.10 | - | 112 | 208 | 0.000 |
| 3 | g14660.t3 | PANTHER | PTHR10459 | DNA LIGASE | 7 | 85 | 0.000 |
| 4 | g14660.t3 | PANTHER | PTHR10459:SF43 | POLY [ADP-RIBOSE] POLYMERASE | 7 | 85 | 0.000 |
| 2 | g14660.t3 | Pfam | PF00645 | Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region | 9 | 83 | 0.000 |
| 1 | g14660.t3 | Pfam | PF00645 | Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region | 125 | 207 | 0.000 |
| 12 | g14660.t3 | ProSiteProfiles | PS50064 | Poly(ADP-ribose) polymerase zinc finger domain profile. | 6 | 88 | 25.644 |
| 11 | g14660.t3 | ProSiteProfiles | PS50064 | Poly(ADP-ribose) polymerase zinc finger domain profile. | 122 | 208 | 26.262 |
| 8 | g14660.t3 | SMART | SM01336 | zf_PARP_3 | 9 | 85 | 0.000 |
| 7 | g14660.t3 | SMART | SM01336 | zf_PARP_3 | 125 | 208 | 0.000 |
| 6 | g14660.t3 | SUPERFAMILY | SSF57716 | Glucocorticoid receptor-like (DNA-binding domain) | 3 | 87 | 0.000 |
| 5 | g14660.t3 | SUPERFAMILY | SSF57716 | Glucocorticoid receptor-like (DNA-binding domain) | 120 | 207 | 0.000 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0003677 | DNA binding | MF |
| GO:0008270 | zinc ion binding | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
