General information for g14829.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Ornithine aminotransferase, mitochondrial.
Parent gene
- The parent gene g14829 is located on chr_4: 2569792..2571099 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g14829 | g14829.t1 | TSS | g14829.t1 | 2569708 | 2569708 |
| chr_4 | g14829 | g14829.t1 | isoform | g14829.t1 | 2569792 | 2571099 |
| chr_4 | g14829 | g14829.t1 | exon | g14829.t1.exon1 | 2569792 | 2571099 |
| chr_4 | g14829 | g14829.t1 | cds | g14829.t1.CDS1 | 2569792 | 2571099 |
| chr_4 | g14829 | g14829.t1 | TTS | g14829.t1 | 2571342 | 2571342 |
Sequences
>g14829.t1 Gene=g14829 Length=1308
ATGTCTCGTTTACATTTGTTCTCACGTGTTGTTCAACTACGTTCACTTTCAACATCGCAA
TCTCGTCTCGGACACGCAGTAAATCTCGATACACTACCACAAAAATCGCGTGATATCATC
AAACGAGAACGACTCGTAACTTGCAATAATTATTCAGCATTGCCAGCTGTTTTATGTGCC
GGCAAAGGCGTGTTTCTTTATGACGTTGATGGAAATAAATATTACGATTATTTGAGCGGT
TATTCAAGTGTAAATCAAGGTCACTGTCATCCAAAAATCATTGATGCACTTGTCAAACAA
GTTACAGTGCTGCATCATACATCCAGGGCTTTTCATAGTGATTTGTTGGTCGAATATGCT
GAATTTCTTACTGATCTATTCAAATATGATGCTATGCTACCTATGAATACTGGCGTTGAA
GCTGCCGAAAGTGCAGTAAAAATAGCTCGCAAATGGGGCTATAAAGTAAAGAAAATTCCC
ACAAACAAAGCAAAAATTATTTTCTGTGAAAACAATTTCTGGGGTCGTTCAATTGCTGCA
GTATCAGCATCAACTGACCCAACTGCCTATGAAAATTATGGACCATTTGTGCCAGGATTT
GTAAACATTCCCTATGATGATATTGAAAGTTTAGAGAAAGAATTGCAGGATGAAAATGTT
TGTGCATTTATGGCTGAACCAATACAAGGTGAAGCAGGTGTGGTTGTGCCATCTGATGGA
TATTTAACAAAAGTTCGTGAACTCTGTACAAAACACAATGTTTTATTTATTGCTGATGAA
ATTCAAACAGGATTGGGAAGAACTGGACGAAGACTTGCAGTTGATCATGAAAATGTTAGA
CCTGATATCATCGTTCTTGGAAAGGCACTTTCAGGTGGTGTGTATCCGATTTCAGCAGTT
CTAGCTGATCGTCATATTATGGATGTTGTTGAACCTGGAACTCATGGATCAACTTATGGT
GGAAATCCTCTTGCTGCTAAAGTCGCGATTGCTGCATTAAAAGTTCTTGAAAATGAAAGA
TTAGCCGAAAATGCTGAAAAAATGGGAAAAATATTAAGACAAGGGTTGAGTGAATTGGAC
AAAGACATTGTATTGGCTTATCGAGGCAAAGGTTTATTGAATGCGATTGTTATCAATAAT
GAGAGAATTGATGCATTTGATTTGTGCTTAAAACTCAAGGAAAATGGTTTATTATCAAAA
CCAACACATGATAATATTCTCAGACTTGCGCCACCATTGATTATTACTGAAGAACAGATC
AATGAATCTCTTGAAATTATCAGAAATACATTGAAAGAGATCAAGTAA
>g14829.t1 Gene=g14829 Length=435
MSRLHLFSRVVQLRSLSTSQSRLGHAVNLDTLPQKSRDIIKRERLVTCNNYSALPAVLCA
GKGVFLYDVDGNKYYDYLSGYSSVNQGHCHPKIIDALVKQVTVLHHTSRAFHSDLLVEYA
EFLTDLFKYDAMLPMNTGVEAAESAVKIARKWGYKVKKIPTNKAKIIFCENNFWGRSIAA
VSASTDPTAYENYGPFVPGFVNIPYDDIESLEKELQDENVCAFMAEPIQGEAGVVVPSDG
YLTKVRELCTKHNVLFIADEIQTGLGRTGRRLAVDHENVRPDIIVLGKALSGGVYPISAV
LADRHIMDVVEPGTHGSTYGGNPLAAKVAIAALKVLENERLAENAEKMGKILRQGLSELD
KDIVLAYRGKGLLNAIVINNERIDAFDLCLKLKENGLLSKPTHDNILRLAPPLIITEEQI
NESLEIIRNTLKEIK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g14829.t1 | CDD | cd00610 | OAT_like | 39 | 431 | 1.36953E-159 |
| 5 | g14829.t1 | Gene3D | G3DSA:3.90.1150.10 | Aspartate Aminotransferase | 47 | 422 | 1.8E-150 |
| 6 | g14829.t1 | Gene3D | G3DSA:3.40.640.10 | - | 90 | 341 | 1.8E-150 |
| 2 | g14829.t1 | PANTHER | PTHR11986 | AMINOTRANSFERASE CLASS III | 36 | 433 | 2.5E-181 |
| 3 | g14829.t1 | PANTHER | PTHR11986:SF18 | ORNITHINE AMINOTRANSFERASE, MITOCHONDRIAL | 36 | 433 | 2.5E-181 |
| 8 | g14829.t1 | PIRSF | PIRSF000521 | Transaminase_4ab_Lys_Orn | 7 | 188 | 7.8E-7 |
| 7 | g14829.t1 | PIRSF | PIRSF000521 | Transaminase_4ab_Lys_Orn | 205 | 434 | 1.5E-36 |
| 1 | g14829.t1 | Pfam | PF00202 | Aminotransferase class-III | 53 | 431 | 4.1E-120 |
| 10 | g14829.t1 | ProSitePatterns | PS00600 | Aminotransferases class-III pyridoxal-phosphate attachment site. | 256 | 293 | - |
| 4 | g14829.t1 | SUPERFAMILY | SSF53383 | PLP-dependent transferases | 47 | 433 | 1.2E-125 |
| 11 | g14829.t1 | TIGRFAM | TIGR01885 | Orn_aminotrans: ornithine–oxo-acid transaminase | 37 | 431 | 2.6E-191 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0004587 | ornithine-oxo-acid transaminase activity | MF |
| GO:0008483 | transaminase activity | MF |
| GO:0003824 | catalytic activity | MF |
| GO:0030170 | pyridoxal phosphate binding | MF |
KEGG
Orthology
- This transcript has been annotated with K00819 (ornithine–oxo-acid transaminase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
