General information for g14829.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Ornithine aminotransferase, mitochondrial.
Parent gene
- The parent gene g14829 is located on chr_4: 2569792..2571099 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g14829 | g14829.t3 | TSS | g14829.t3 | 2569708 | 2569708 |
| chr_4 | g14829 | g14829.t3 | isoform | g14829.t3 | 2569792 | 2571099 |
| chr_4 | g14829 | g14829.t3 | exon | g14829.t3.exon1 | 2569792 | 2570527 |
| chr_4 | g14829 | g14829.t3 | cds | g14829.t3.CDS1 | 2569792 | 2570527 |
| chr_4 | g14829 | g14829.t3 | exon | g14829.t3.exon2 | 2570696 | 2571099 |
| chr_4 | g14829 | g14829.t3 | cds | g14829.t3.CDS2 | 2570696 | 2571099 |
| chr_4 | g14829 | g14829.t3 | TTS | g14829.t3 | 2571342 | 2571342 |
Sequences
>g14829.t3 Gene=g14829 Length=1140
ATGTCTCGTTTACATTTGTTCTCACGTGTTGTTCAACTACGTTCACTTTCAACATCGCAA
TCTCGTCTCGGACACGCAGTAAATCTCGATACACTACCACAAAAATCGCGTGATATCATC
AAACGAGAACGACTCGTAACTTGCAATAATTATTCAGCATTGCCAGCTGTTTTATGTGCC
GGCAAAGGCGTGTTTCTTTATGACGTTGATGGAAATAAATATTACGATTATTTGAGCGGT
TATTCAAGTGTAAATCAAGGTCACTGTCATCCAAAAATCATTGATGCACTTGTCAAACAA
GTTACAGTGCTGCATCATACATCCAGGGCTTTTCATAGTGATTTGTTGGTCGAATATGCT
GAATTTCTTACTGATCTATTCAAATATGATGCTATGCTACCTATGAATACTGGCGTTGAA
GCTGCCGAAAGTGCAGTAAAAATAGCTCGCAAATGGGGCTATAAAGTAAAGAAAATTCCC
ACAAACAAAGCAAAAATTATTTTCTGTGAAAACAATTTCTGGGGTCGTTCAATTGCTGCA
GTATCAGCATCAACTGACCCAACTGCCTATGAAAATTATGGACCATTTGTGCCAGGATTT
GTAAACATTCCCTATGATGATATTGAAAGTTTAGAGAAAGAATTGCAGGATGAAAATGTT
TGTGCATTTATGGCTGAACCAATACAAGGTGAAGCAGGTGTGGTTGTGCCATCTGATGGA
TATTTAACAAAAGTTCCTGATCGTCATATTATGGATGTTGTTGAACCTGGAACTCATGGA
TCAACTTATGGTGGAAATCCTCTTGCTGCTAAAGTCGCGATTGCTGCATTAAAAGTTCTT
GAAAATGAAAGATTAGCCGAAAATGCTGAAAAAATGGGAAAAATATTAAGACAAGGGTTG
AGTGAATTGGACAAAGACATTGTATTGGCTTATCGAGGCAAAGGTTTATTGAATGCGATT
GTTATCAATAATGAGAGAATTGATGCATTTGATTTGTGCTTAAAACTCAAGGAAAATGGT
TTATTATCAAAACCAACACATGATAATATTCTCAGACTTGCGCCACCATTGATTATTACT
GAAGAACAGATCAATGAATCTCTTGAAATTATCAGAAATACATTGAAAGAGATCAAGTAA
>g14829.t3 Gene=g14829 Length=379
MSRLHLFSRVVQLRSLSTSQSRLGHAVNLDTLPQKSRDIIKRERLVTCNNYSALPAVLCA
GKGVFLYDVDGNKYYDYLSGYSSVNQGHCHPKIIDALVKQVTVLHHTSRAFHSDLLVEYA
EFLTDLFKYDAMLPMNTGVEAAESAVKIARKWGYKVKKIPTNKAKIIFCENNFWGRSIAA
VSASTDPTAYENYGPFVPGFVNIPYDDIESLEKELQDENVCAFMAEPIQGEAGVVVPSDG
YLTKVPDRHIMDVVEPGTHGSTYGGNPLAAKVAIAALKVLENERLAENAEKMGKILRQGL
SELDKDIVLAYRGKGLLNAIVINNERIDAFDLCLKLKENGLLSKPTHDNILRLAPPLIIT
EEQINESLEIIRNTLKEIK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 13 | g14829.t3 | CDD | cd00610 | OAT_like | 39 | 375 | 0.0e+00 |
| 9 | g14829.t3 | Gene3D | G3DSA:3.40.640.10 | - | 90 | 248 | 0.0e+00 |
| 8 | g14829.t3 | Gene3D | G3DSA:3.90.1150.10 | Aspartate Aminotransferase | 254 | 379 | 0.0e+00 |
| 3 | g14829.t3 | PANTHER | PTHR11986 | AMINOTRANSFERASE CLASS III | 36 | 246 | 0.0e+00 |
| 5 | g14829.t3 | PANTHER | PTHR11986:SF18 | ORNITHINE AMINOTRANSFERASE, MITOCHONDRIAL | 36 | 246 | 0.0e+00 |
| 4 | g14829.t3 | PANTHER | PTHR11986 | AMINOTRANSFERASE CLASS III | 247 | 377 | 0.0e+00 |
| 6 | g14829.t3 | PANTHER | PTHR11986:SF18 | ORNITHINE AMINOTRANSFERASE, MITOCHONDRIAL | 247 | 377 | 0.0e+00 |
| 10 | g14829.t3 | PIRSF | PIRSF000521 | Transaminase_4ab_Lys_Orn | 7 | 187 | 6.0e-07 |
| 12 | g14829.t3 | PIRSF | PIRSF000521 | Transaminase_4ab_Lys_Orn | 205 | 253 | 3.2e-02 |
| 11 | g14829.t3 | PIRSF | PIRSF000521 | Transaminase_4ab_Lys_Orn | 247 | 378 | 0.0e+00 |
| 1 | g14829.t3 | Pfam | PF00202 | Aminotransferase class-III | 53 | 245 | 0.0e+00 |
| 2 | g14829.t3 | Pfam | PF00202 | Aminotransferase class-III | 248 | 375 | 0.0e+00 |
| 7 | g14829.t3 | SUPERFAMILY | SSF53383 | PLP-dependent transferases | 34 | 377 | 0.0e+00 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0004587 | ornithine-oxo-acid transaminase activity | MF |
| GO:0008483 | transaminase activity | MF |
| GO:0003824 | catalytic activity | MF |
| GO:0030170 | pyridoxal phosphate binding | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed