General information for g14878.t14
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Glutamine–fructose-6-phosphate aminotransferase [isomerizing] 2.
Parent gene
- The parent gene g14878 is located on chr_4: 2811719..2812274 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g14878 | g14878.t14 | isoform | g14878.t14 | 2801537 | 2812274 |
| chr_4 | g14878 | g14878.t14 | exon | g14878.t14.exon1 | 2801537 | 2801540 |
| chr_4 | g14878 | g14878.t14 | cds | g14878.t14.CDS1 | 2801537 | 2801540 |
| chr_4 | g14878 | g14878.t14 | exon | g14878.t14.exon2 | 2806040 | 2806551 |
| chr_4 | g14878 | g14878.t14 | cds | g14878.t14.CDS2 | 2806040 | 2806551 |
| chr_4 | g14878 | g14878.t14 | exon | g14878.t14.exon3 | 2806615 | 2806756 |
| chr_4 | g14878 | g14878.t14 | cds | g14878.t14.CDS3 | 2806615 | 2806756 |
| chr_4 | g14878 | g14878.t14 | exon | g14878.t14.exon4 | 2810225 | 2810382 |
| chr_4 | g14878 | g14878.t14 | cds | g14878.t14.CDS4 | 2810225 | 2810382 |
| chr_4 | g14878 | g14878.t14 | exon | g14878.t14.exon5 | 2810565 | 2811404 |
| chr_4 | g14878 | g14878.t14 | cds | g14878.t14.CDS5 | 2810565 | 2811404 |
| chr_4 | g14878 | g14878.t14 | exon | g14878.t14.exon6 | 2811473 | 2811736 |
| chr_4 | g14878 | g14878.t14 | cds | g14878.t14.CDS6 | 2811473 | 2811736 |
| chr_4 | g14878 | g14878.t14 | exon | g14878.t14.exon7 | 2811799 | 2812274 |
| chr_4 | g14878 | g14878.t14 | cds | g14878.t14.CDS7 | 2811799 | 2811909 |
| chr_4 | g14878 | g14878.t14 | TSS | g14878.t14 | NA | NA |
| chr_4 | g14878 | g14878.t14 | TTS | g14878.t14 | NA | NA |
Sequences
>g14878.t14 Gene=g14878 Length=2396
ATGTGTATTTTTGCATACTTGAACTATCTAACACCAAAAACTCGTCGTGAGGTTCTCGAA
TATCTTGTAACCGGCTTGAAGCGTCTCGAGTATCGTGGCTATGATTCGGCTGGTGTTGCT
GTGGATAGCGAGGATGGAAAAGGCATCGTGTTAGTAAAGCAAACTGGCAAGGTTAAAGCA
CTTGAGGAGGCCATCAATGAAAGCATGATTGGCCATGACATCGACAGTCCATTGATGTCT
CATTGCGGTATCTCACATACACGTTGGGCTACTCATGGTGAACCAAGTGAGCTCAATTCA
CATCCACAACGAAGTGATGAAGAAAATAGCTTTGTTGTTGTTCACAATGGAATTATCACC
AATTATAAGGATGTTAAAACTTTCTTGGAAAAACGTGGCTATAAATTTGAGTCTGAAACT
GATACTGAAATCATTGCAAAACTTGTTCATCATTTATACATGCAACATCCAAATTATTCA
TTTAGAGAGTTGGTTGAACAAGTCATTCAGCAATTGGAAGGTGCATTTTCATTGGCCTTC
AAATCAAAACACTTTCCTGGTGAATGTGTCGCCACGCGACGTGGTTCACCACTCCTTGTT
GGAATAAAGACTAAAACACGTCTCGCAACTGATCATATTCCGATTTTGTATGGCAAAGAA
CATCGTCCTCATGGCGCTAATCGTGAAGTTCCAATGATGCCAAGAACTGAAAGCACAAGT
GAATTTCAACCACTCGAAGATAAAGAAGTTGAATATTTCTTTGCATCTGATGCATCAGCT
GTTATTGAACATACAAATCGTGTCATCTATTTGGAAGACGATGACGTCGCAGCAGTCAAA
GAAGGCGCTCTCAGTATTCATCGCCTTAAAAAATCAATGGACGATTCACACGCTCGTGAA
ATTATCACATTAAAAATGGAAATTCAACAAATTATGAAAGGAAATTACGAATATTTCATG
CAAAAGGAAATTTTCGAACAACCTGAATCAGTGGTCAATACAATGCGTGGTCGTGTAAAT
TTAAATGATAATACAGTAACACTTGGTGGAATTAAGGAATACATTCCAGAAATTAAGCGT
TGTCGTCGTCTTATGTTGATTGGTTGTGGAACATCATATCACAGTGCAGTTGCAACAAGA
CAATTACTTGAAGAATTAACAGAATTGCCAGTTATGGTTGAACTTGCAAGTGATTTCTTA
GATCGAAACACACCAATTTTCCGTGATGACGTTTGTTTCTTTATTTCACAATCTGGTGAA
ACTGCCGACACATTAATGGCATTGAGATATTGTAAACAACGTGGTGCATTGATTGTTGGT
ATCACCAACACTGTCGGCAGTTCTATCTGTCGTGAATCACATTGTGGTGTGCATATTAAT
GCTGGACCTGAAATTGGTGTTGCATCAACAAAAGCCTACACATCGCAATTCATTTCACTT
GTTATGTTTGGTCTTGTTATGAGTGAAGATCGAATTTCATTGCAAACAAGAAGACAAGAA
ATTTTAAACGGTTTAAAGAATTTGGATGCCCAAATTAAAGATGTATTGAAACTTGATTCA
CAAGTATTGGATATTGTTAAAGATTTATATCAACAAAAGAGTTTGCTGATTATGGGACGT
GGTTATAATTTTGCTACATGTATGGAAGGTGCTTTGAAAGTGAAAGAATTGACATACATG
CATTGTGAAGGAATCATGGCTGGTGAACTTAAACATGGACCACTTGCTCTTGTTGATGAT
ATGATGCCAATTGTGATGATTGTTATGCGTGATGGAGTTTATAATAAGACAATCAATGCC
ATACAACAAGTTAAAGCTAGAGGAGGTCAACCAATTGTCATTTGTGAAGAAAATGACAAG
GAAACAATGGTGTTTGCCCATAAAGTTCTTGAAGTGCCGAAAACTGTTGATTGCCTTCAA
GGAATTTTGACTGTCATTCCAATGCAACTTCTTTCATACCACATTGCTGTCTTGCGTGGT
TGCAATGTTGATTGTCCAAGAAATCTCGCAAAATCTGTCACTGTGGAGTAAAAATTTCAT
TTCAAGTATTCTATATCGTCTTTTAAGGAATTTTCTCTTTTTTTAAATTTTTATTATTTT
TAGTCAGATTTTTTTGTACTTATGAAAAATTTCGAGTTTTTAAAAGGGATTAAAAATGTC
TTTTAAAAAAATTAGGTAATTTTATTTTATGAAGATTTTTTTATTTACTTAATTTTTCCA
CTTCAATTCAATTGAAATCATTTTTTATTATTTGAATATTTCTGAAAACATTTAAACATT
TAGCATTTTTATTTCTTATACGTAAATAAGTAAGAAAAATAAATAAAAATCGATATTATT
AAACTTTGTAAAAATTTGTTTTATTTTAAAGAAAAATTAAAATTTTTAATTTTTTT
>g14878.t14 Gene=g14878 Length=676
MCIFAYLNYLTPKTRREVLEYLVTGLKRLEYRGYDSAGVAVDSEDGKGIVLVKQTGKVKA
LEEAINESMIGHDIDSPLMSHCGISHTRWATHGEPSELNSHPQRSDEENSFVVVHNGIIT
NYKDVKTFLEKRGYKFESETDTEIIAKLVHHLYMQHPNYSFRELVEQVIQQLEGAFSLAF
KSKHFPGECVATRRGSPLLVGIKTKTRLATDHIPILYGKEHRPHGANREVPMMPRTESTS
EFQPLEDKEVEYFFASDASAVIEHTNRVIYLEDDDVAAVKEGALSIHRLKKSMDDSHARE
IITLKMEIQQIMKGNYEYFMQKEIFEQPESVVNTMRGRVNLNDNTVTLGGIKEYIPEIKR
CRRLMLIGCGTSYHSAVATRQLLEELTELPVMVELASDFLDRNTPIFRDDVCFFISQSGE
TADTLMALRYCKQRGALIVGITNTVGSSICRESHCGVHINAGPEIGVASTKAYTSQFISL
VMFGLVMSEDRISLQTRRQEILNGLKNLDAQIKDVLKLDSQVLDIVKDLYQQKSLLIMGR
GYNFATCMEGALKVKELTYMHCEGIMAGELKHGPLALVDDMMPIVMIVMRDGVYNKTINA
IQQVKARGGQPIVICEENDKETMVFAHKVLEVPKTVDCLQGILTVIPMQLLSYHIAVLRG
CNVDCPRNLAKSVTVE
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 16 | g14878.t14 | CDD | cd00714 | GFAT | 3 | 279 | 0.000 |
| 15 | g14878.t14 | CDD | cd05008 | SIS_GlmS_GlmD_1 | 363 | 488 | 0.000 |
| 14 | g14878.t14 | CDD | cd05009 | SIS_GlmS_GlmD_2 | 521 | 674 | 0.000 |
| 8 | g14878.t14 | Gene3D | G3DSA:3.40.50.10490 | - | 314 | 675 | 0.000 |
| 9 | g14878.t14 | Gene3D | G3DSA:3.40.50.10490 | - | 514 | 661 | 0.000 |
| 4 | g14878.t14 | PANTHER | PTHR10937:SF10 | GLUTAMINE–FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE [ISOMERIZING] 2 | 2 | 676 | 0.000 |
| 5 | g14878.t14 | PANTHER | PTHR10937 | GLUCOSAMINE–FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE, ISOMERIZING | 2 | 676 | 0.000 |
| 3 | g14878.t14 | Pfam | PF13522 | Glutamine amidotransferase domain | 80 | 190 | 0.000 |
| 2 | g14878.t14 | Pfam | PF01380 | SIS domain | 358 | 483 | 0.000 |
| 1 | g14878.t14 | Pfam | PF01380 | SIS domain | 529 | 658 | 0.000 |
| 13 | g14878.t14 | ProSiteProfiles | PS51278 | Glutamine amidotransferase type 2 domain profile. | 2 | 282 | 36.170 |
| 11 | g14878.t14 | ProSiteProfiles | PS51464 | SIS domain profile. | 354 | 493 | 27.808 |
| 12 | g14878.t14 | ProSiteProfiles | PS51464 | SIS domain profile. | 525 | 666 | 24.430 |
| 6 | g14878.t14 | SUPERFAMILY | SSF56235 | N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 14 | 288 | 0.000 |
| 7 | g14878.t14 | SUPERFAMILY | SSF53697 | SIS domain | 313 | 676 | 0.000 |
| 10 | g14878.t14 | TIGRFAM | TIGR01135 | glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) | 250 | 676 | 0.000 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:1901135 | carbohydrate derivative metabolic process | BP |
| GO:0097367 | carbohydrate derivative binding | MF |
| GO:1901137 | carbohydrate derivative biosynthetic process | BP |
| GO:0004360 | glutamine-fructose-6-phosphate transaminase (isomerizing) activity | MF |
KEGG
Orthology
- This transcript has been annotated with K00820 (glutamine—fructose-6-phosphate transaminase (isomerizing))
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed