General information for g15013.t18
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Chymotrypsin-2.
Parent gene
- The parent gene g15013 is located on chr_4: 3513904..3515591 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g15013 | g15013.t18 | TSS | g15013.t18 | 3513859 | 3513859 |
| chr_4 | g15013 | g15013.t18 | isoform | g15013.t18 | 3513904 | 3515116 |
| chr_4 | g15013 | g15013.t18 | exon | g15013.t18.exon1 | 3513904 | 3513949 |
| chr_4 | g15013 | g15013.t18 | exon | g15013.t18.exon2 | 3514053 | 3514541 |
| chr_4 | g15013 | g15013.t18 | cds | g15013.t18.CDS1 | 3514264 | 3514541 |
| chr_4 | g15013 | g15013.t18 | exon | g15013.t18.exon3 | 3514600 | 3514700 |
| chr_4 | g15013 | g15013.t18 | cds | g15013.t18.CDS2 | 3514600 | 3514700 |
| chr_4 | g15013 | g15013.t18 | exon | g15013.t18.exon4 | 3515087 | 3515116 |
| chr_4 | g15013 | g15013.t18 | cds | g15013.t18.CDS3 | 3515087 | 3515115 |
| chr_4 | g15013 | g15013.t18 | TTS | g15013.t18 | 3515192 | 3515192 |
Sequences
>g15013.t18 Gene=g15013 Length=666
ATGTTTAAATTTATCGTTCTTTTGGGCCTTGTGTCATCAGCACTCTATCATCAGGAAATG
CTCATTTCTGTGGTGGTTTCATTATTAACAATCGCTGGGTTGGATCAGCTGCTCACTGCA
CAGTTGGACGTACTGCCGCAAACACAATCTCAGTTGTTGGTACCAACAGTCGTACATCAG
GTGGTGTTGCTCACAGTACATCACGCATTGTCAACCATCCAAGTTACAATGGCAACACAT
TGGCCAATGATATTTCAATGGTTTTCACTGCATCAACAATTACCTTCAATAACTTGGTTC
AACCAATCACTCTTGGATCAGCTCATGTTGGCGGTGGTGTTTCAGCAACTGCATCAGGTT
GGGGTCAAACATCACATCCAGGCTCAGCTGCTGCCAATTTGCAATTCTTAACTAAACCAA
CTTTGACAAATGCTGACTGCCGTGCTCGTCACTCTGCTGGAAATGCTGCCCGTGTCTTTG
ACAACACTATCTGTACATTCTTGAGAGCAGGAGCTGGTATGTGCATGGGTGACAGTGGTG
GCCCATTGATTGCTGGTGGTACAGTTATTGGTGCAGTTTCATGGGGTATTGCATGCGCTC
AAGGATTCCCTGATGTTTTCGCTGTAATGACTCAAACATCGCACATGGATGATCAACCAA
ATGTAA
>g15013.t18 Gene=g15013 Length=136
MVFTASTITFNNLVQPITLGSAHVGGGVSATASGWGQTSHPGSAAANLQFLTKPTLTNAD
CRARHSAGNAARVFDNTICTFLRAGAGMCMGDSGGPLIAGGTVIGAVSWGIACAQGFPDV
FAVMTQTSHMDDQPNV
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 8 | g15013.t18 | Gene3D | G3DSA:2.40.10.10 | - | 4 | 16 | 7.8E-25 |
| 7 | g15013.t18 | Gene3D | G3DSA:2.40.10.10 | - | 17 | 124 | 7.8E-25 |
| 2 | g15013.t18 | PANTHER | PTHR24256:SF458 | IP10114P-RELATED | 6 | 125 | 8.7E-20 |
| 3 | g15013.t18 | PANTHER | PTHR24256 | TRYPTASE-RELATED | 6 | 125 | 8.7E-20 |
| 1 | g15013.t18 | Pfam | PF00089 | Trypsin | 5 | 125 | 2.6E-22 |
| 6 | g15013.t18 | ProSitePatterns | PS00135 | Serine proteases, trypsin family, serine active site. | 87 | 98 | - |
| 9 | g15013.t18 | ProSiteProfiles | PS50240 | Serine proteases, trypsin domain profile. | 1 | 136 | 13.472 |
| 5 | g15013.t18 | SMART | SM00020 | trypsin_2 | 1 | 125 | 2.9E-4 |
| 4 | g15013.t18 | SUPERFAMILY | SSF50494 | Trypsin-like serine proteases | 4 | 122 | 3.95E-27 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0004252 | serine-type endopeptidase activity | MF |
| GO:0006508 | proteolysis | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed