General information for g15083.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Cytochrome P450 4d1.
Parent gene
- The parent gene g15083 is located on chr_4: 3841168..3845808 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g15083 | g15083.t1 | TSS | g15083.t1 | 3841047 | 3841047 |
| chr_4 | g15083 | g15083.t1 | isoform | g15083.t1 | 3841168 | 3845808 |
| chr_4 | g15083 | g15083.t1 | exon | g15083.t1.exon1 | 3841168 | 3841314 |
| chr_4 | g15083 | g15083.t1 | cds | g15083.t1.CDS1 | 3841168 | 3841314 |
| chr_4 | g15083 | g15083.t1 | exon | g15083.t1.exon2 | 3841426 | 3841633 |
| chr_4 | g15083 | g15083.t1 | cds | g15083.t1.CDS2 | 3841426 | 3841633 |
| chr_4 | g15083 | g15083.t1 | exon | g15083.t1.exon3 | 3841698 | 3842171 |
| chr_4 | g15083 | g15083.t1 | cds | g15083.t1.CDS3 | 3841698 | 3842171 |
| chr_4 | g15083 | g15083.t1 | exon | g15083.t1.exon4 | 3842765 | 3842929 |
| chr_4 | g15083 | g15083.t1 | cds | g15083.t1.CDS4 | 3842765 | 3842929 |
| chr_4 | g15083 | g15083.t1 | exon | g15083.t1.exon5 | 3842994 | 3843156 |
| chr_4 | g15083 | g15083.t1 | cds | g15083.t1.CDS5 | 3842994 | 3843156 |
| chr_4 | g15083 | g15083.t1 | exon | g15083.t1.exon6 | 3843221 | 3843270 |
| chr_4 | g15083 | g15083.t1 | cds | g15083.t1.CDS6 | 3843221 | 3843270 |
| chr_4 | g15083 | g15083.t1 | exon | g15083.t1.exon7 | 3845609 | 3845671 |
| chr_4 | g15083 | g15083.t1 | cds | g15083.t1.CDS7 | 3845609 | 3845671 |
| chr_4 | g15083 | g15083.t1 | exon | g15083.t1.exon8 | 3845729 | 3845808 |
| chr_4 | g15083 | g15083.t1 | cds | g15083.t1.CDS8 | 3845729 | 3845808 |
| chr_4 | g15083 | g15083.t1 | TTS | g15083.t1 | NA | NA |
Sequences
>g15083.t1 Gene=g15083 Length=1350
ATGGCAATAGTTGCAAAATTACCTGGACCATATCGATGGCCATTTGTTGGAAATGCAGCA
CTGTTCATTTGGAAATCACCACCTGAAATGATTAATATAATAACAGAAATTCATCGGCAG
TTTCCTCGTATAATTGCCTCATGCTTGCAAACTGGACTTTTGACAGCAACTGGTAAAAAA
TGGTTTCAACGACGCAAAGTCATCACACCGGCATTTCATTTTAAAATTCTTGACCAATTT
GTTGAAATTTTTGATAAGCAAAGTGCAGTTTTTGTGGAGAATCTTGCAAAATCAAAAGGT
CAACCTTTGGACGTTTTTCAACCTATCACACTTTGCGCACTCGACATTATCTGTGAAACT
GCAATGGGTGTACAAATACAAGCACAAATTAATTCAGATTCTGTTTATGTACAAGCTGTA
AAAAGAGTAAATGCTTTTTTTTGTTTACATAAGGGAAATCCCAGAATTAAAAATAATTTT
TTTCATATCTGTAGAATCAGTGGACTATTAAGTAAGAGGATTTTCACTTTTTATCTTCGA
AATGATTTTATATTCAATTTAACACCATTGAAAAGACGACAAGATAAATTGTTGAAAATT
TTACATGGTTTTACTGATGAAGTGATTGTTTCACGACGTGCTGAACTTATGAATGATAAA
AAACAAGATTCTTCATCAAATCATGATCAAGATGATATTGGAGTTAAAAAGAAGATGGCA
TTTCTTGATATTTTGTTGCAGTCAACAATTGAAGGGAAACCATTGACAAATATGGATATA
AGAGAAAAGTGGATACTTTTATGTTTGAGGGCCATGACACAACTAGCAGCATATGAAGAA
GTTCGACATGTGATCGGTGATGATTTGGATACTCCAGTTACAATAAAACTTCTCAATGAT
CTCAATTATCTTGAAATGGTTATAAAAGAGACTTTGAGACTTTATCCAAGTGTTCCTATG
TATGGTAGAAAAATGCAAGAAAATATTGACATGAATGGATTTATAATTCCAAAAGGTTCA
AATATTGGTATTTCACCTATTTTTATGGCTCGTGATCCAACATTGTGGGAAAATCCTTTT
GAATTTATTCCTGAAAGATTCGAGTCTGATAATCAATATCATCCTTATTTAAATGTTCCA
TTCAGTGCTGGTCCAAGAAATTGCATCGGGCAAAAGTTTGCAATGCTTGAAATGAAGAGC
ACAATAACACATATGCTGTATCAGCTTGCACAAACACTTGCATTTTTACCATTTCTTTTG
AACAATCAATGTAATTGCTATTGCCCAATTCTTGAGTGTGTAGTTGGATGTGTCCTCAAT
GTTGCCACCTGTACTTGCGATCCTATTTAA
>g15083.t1 Gene=g15083 Length=449
MAIVAKLPGPYRWPFVGNAALFIWKSPPEMINIITEIHRQFPRIIASCLQTGLLTATGKK
WFQRRKVITPAFHFKILDQFVEIFDKQSAVFVENLAKSKGQPLDVFQPITLCALDIICET
AMGVQIQAQINSDSVYVQAVKRVNAFFCLHKGNPRIKNNFFHICRISGLLSKRIFTFYLR
NDFIFNLTPLKRRQDKLLKILHGFTDEVIVSRRAELMNDKKQDSSSNHDQDDIGVKKKMA
FLDILLQSTIEGKPLTNMDIREKWILLCLRAMTQLAAYEEVRHVIGDDLDTPVTIKLLND
LNYLEMVIKETLRLYPSVPMYGRKMQENIDMNGFIIPKGSNIGISPIFMARDPTLWENPF
EFIPERFESDNQYHPYLNVPFSAGPRNCIGQKFAMLEMKSTITHMLYQLAQTLAFLPFLL
NNQCNCYCPILECVVGCVLNVATCTCDPI
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 16 | g15083.t1 | Gene3D | G3DSA:1.10.630.10 | Cytochrome p450 | 3 | 267 | 1.9E-25 |
| 15 | g15083.t1 | Gene3D | G3DSA:1.10.630.10 | Cytochrome p450 | 268 | 415 | 5.9E-50 |
| 2 | g15083.t1 | PANTHER | PTHR24291:SF143 | CYTOCHROME P450 4D1-RELATED | 45 | 262 | 2.9E-111 |
| 4 | g15083.t1 | PANTHER | PTHR24291 | CYTOCHROME P450 FAMILY 4 | 45 | 262 | 2.9E-111 |
| 3 | g15083.t1 | PANTHER | PTHR24291:SF143 | CYTOCHROME P450 4D1-RELATED | 270 | 407 | 2.9E-111 |
| 5 | g15083.t1 | PANTHER | PTHR24291 | CYTOCHROME P450 FAMILY 4 | 270 | 407 | 2.9E-111 |
| 11 | g15083.t1 | PRINTS | PR00465 | E-class P450 group IV signature | 301 | 317 | 2.1E-14 |
| 6 | g15083.t1 | PRINTS | PR00385 | P450 superfamily signature | 306 | 317 | 3.4E-8 |
| 10 | g15083.t1 | PRINTS | PR00465 | E-class P450 group IV signature | 334 | 348 | 2.1E-14 |
| 9 | g15083.t1 | PRINTS | PR00465 | E-class P450 group IV signature | 350 | 368 | 2.1E-14 |
| 7 | g15083.t1 | PRINTS | PR00385 | P450 superfamily signature | 379 | 388 | 3.4E-8 |
| 8 | g15083.t1 | PRINTS | PR00385 | P450 superfamily signature | 388 | 399 | 3.4E-8 |
| 12 | g15083.t1 | PRINTS | PR00465 | E-class P450 group IV signature | 388 | 406 | 2.1E-14 |
| 1 | g15083.t1 | Pfam | PF00067 | Cytochrome P450 | 49 | 406 | 3.0E-67 |
| 14 | g15083.t1 | ProSitePatterns | PS00086 | Cytochrome P450 cysteine heme-iron ligand signature. | 381 | 390 | - |
| 13 | g15083.t1 | SUPERFAMILY | SSF48264 | Cytochrome P450 | 8 | 408 | 9.43E-79 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0020037 | heme binding | MF |
| GO:0016705 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | MF |
| GO:0005506 | iron ion binding | MF |
| GO:0004497 | monooxygenase activity | MF |
| GO:0055114 | NA | NA |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed