General information for g15166.t4
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Cytosolic non-specific dipeptidase.
Parent gene
- The parent gene g15166 is located on chr_4: 4213967..4214744 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g15166 | g15166.t4 | TSS | g15166.t4 | 4212692 | 4212692 |
| chr_4 | g15166 | g15166.t4 | isoform | g15166.t4 | 4212807 | 4214744 |
| chr_4 | g15166 | g15166.t4 | exon | g15166.t4.exon1 | 4212807 | 4212841 |
| chr_4 | g15166 | g15166.t4 | cds | g15166.t4.CDS1 | 4212807 | 4212841 |
| chr_4 | g15166 | g15166.t4 | exon | g15166.t4.exon2 | 4212945 | 4213183 |
| chr_4 | g15166 | g15166.t4 | cds | g15166.t4.CDS2 | 4212945 | 4213183 |
| chr_4 | g15166 | g15166.t4 | exon | g15166.t4.exon3 | 4213530 | 4213908 |
| chr_4 | g15166 | g15166.t4 | cds | g15166.t4.CDS3 | 4213530 | 4213908 |
| chr_4 | g15166 | g15166.t4 | exon | g15166.t4.exon4 | 4213967 | 4214744 |
| chr_4 | g15166 | g15166.t4 | cds | g15166.t4.CDS4 | 4213967 | 4214744 |
| chr_4 | g15166 | g15166.t4 | TTS | g15166.t4 | 4214803 | 4214803 |
Sequences
>g15166.t4 Gene=g15166 Length=1431
ATGAGTTTGCCGGAAAAATTGGAGAAATTGTTTGGTTATATCGATCAAAACAAAGCAAAA
TACATTGAAACTTTGACTGAAGCTGTTGCGATAAAATCAGTATCAGCTTGGCCTAATTGT
CGAAATGAATGTCAACGTATGATTGATTTTGCTCAGAAAAAAATGGAAGCACTTGGAATC
AAGTGTGAACAAGTCGATATTGGCATGCAAACTTTACCTGATGGAACAACTTTGAAACTT
CCCAATGTTGTAATGGGAGTACTTGGAAATGTAACAAAGAAGACAATTGTTGTTTATGGA
CATTTAGATGTTCAACCAGCATTGAAAGAAGACGGTTGGGACACTGATCCTTTTATTCTC
ACTTTAAAGGACGGTAAATTATATGGTCGTGGTTCTAGTGACGACAAAGGTCCAGTATTA
GGCTGGCTTAATGCAATTGAGGCTTATCAAAAGTTGGGACTTGATGTGCCAGTGAATTTG
AAATTTGTTTTTGAAGGAATGGAAGAAAGTGGCTCAGAAGGTCTCGATGATCTTTTGGTT
GCTCGCAAAGATTGGTTCAAAGATGTCGATTATGTTTGCATTAGTGACAATTATTGGTTG
GGCAATCAACATCCTTGCATCACTTATGGTCTGAGAGGCATTTGCTACTTTGGCTTAGAA
ATTACTTGTGCATCAAAAGATTTGCATTCAGGTGTCTTTGGCGGTGCTGTACATGAAGCT
ATGACTGATTTGATTCATTTAATGTCAACACTTGTTGATGTAAATGGAAAAATCTTAATT
CCTGGAATTTATGATGATGTTGCTCCATTGCTTCCAAATGAAAATGAAATTTATGAAAAA
ATTTCATTCGATGTTGAAGCTTTCCGTCAAAGTGTTGGTGCACCAGGCAAATTGATGCAT
GACTCAAAAACTAAATTGCTTCAGCACAGATGGCGTTATCCAAGTCTTTCATTGCATGGT
GTTGAAGGTGCTTTCTATGAGCCTGGACAAAAGACTGTAATTCCAAGAAAAGTAATTGGA
AAATTCTCAATTCGTGCTGTCCCGAATCAAGAGCCAGAAAAGATTGAAAAACTTGTTGTT
GATTATGTGACTCGAAAATTTGCTGAATTAAAAAGCCCAAATGAAATTAAATGTTATATG
GCTCATGGTGGTCGACCATGGACAGAAAATCCTAACCATGAGCATTATCAAGCTGCTGTT
CGTGCAACTAAGCATGTCTATAAAGTAGAGCCTGATATGACACGTGAAGGTGGGTCAATT
CCGGTCACTCTTACTTTCCAAGAAGTTTCTGGAAAGAATGTACTGTTGCTGCCCATGGGA
TGTGGTGACGATGGCGCTCACAGCCAAAACGAGAAAATTGATGTTCGCAATTATATTGAA
GGAAGCAAATTACTTGGTGCTTACTTGTATGAAGTTGCTCAAATTCAATAA
>g15166.t4 Gene=g15166 Length=476
MSLPEKLEKLFGYIDQNKAKYIETLTEAVAIKSVSAWPNCRNECQRMIDFAQKKMEALGI
KCEQVDIGMQTLPDGTTLKLPNVVMGVLGNVTKKTIVVYGHLDVQPALKEDGWDTDPFIL
TLKDGKLYGRGSSDDKGPVLGWLNAIEAYQKLGLDVPVNLKFVFEGMEESGSEGLDDLLV
ARKDWFKDVDYVCISDNYWLGNQHPCITYGLRGICYFGLEITCASKDLHSGVFGGAVHEA
MTDLIHLMSTLVDVNGKILIPGIYDDVAPLLPNENEIYEKISFDVEAFRQSVGAPGKLMH
DSKTKLLQHRWRYPSLSLHGVEGAFYEPGQKTVIPRKVIGKFSIRAVPNQEPEKIEKLVV
DYVTRKFAELKSPNEIKCYMAHGGRPWTENPNHEHYQAAVRATKHVYKVEPDMTREGGSI
PVTLTFQEVSGKNVLLLPMGCGDDGAHSQNEKIDVRNYIEGSKLLGAYLYEVAQIQ
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 10 | g15166.t4 | CDD | cd05676 | M20_dipept_like_CNDP | 10 | 475 | 0.0 |
| 8 | g15166.t4 | Gene3D | G3DSA:3.40.630.10 | Zn peptidases | 17 | 465 | 2.8E-189 |
| 7 | g15166.t4 | Gene3D | G3DSA:3.30.70.360 | - | 212 | 386 | 2.8E-189 |
| 3 | g15166.t4 | PANTHER | PTHR43270 | BETA-ALA-HIS DIPEPTIDASE | 6 | 475 | 1.0E-219 |
| 4 | g15166.t4 | PANTHER | PTHR43270:SF11 | CYTOSOLIC NON-SPECIFIC DIPEPTIDASE | 6 | 475 | 1.0E-219 |
| 9 | g15166.t4 | PIRSF | PIRSF037242 | CNDP_dipeptidase | 1 | 476 | 8.3E-229 |
| 2 | g15166.t4 | Pfam | PF01546 | Peptidase family M20/M25/M40 | 98 | 470 | 3.8E-37 |
| 1 | g15166.t4 | Pfam | PF07687 | Peptidase dimerisation domain | 210 | 368 | 2.7E-14 |
| 6 | g15166.t4 | ProSitePatterns | PS00759 | ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. | 132 | 171 | - |
| 5 | g15166.t4 | SUPERFAMILY | SSF53187 | Zn-dependent exopeptidases | 8 | 474 | 5.14E-64 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0070573 | metallodipeptidase activity | MF |
| GO:0016787 | hydrolase activity | MF |
KEGG
Orthology
- This transcript has been annotated with K08660 (cytosolic nonspecific dipeptidase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
