Gene loci information

Transcript annotation

  • This transcript has been annotated as ATP-binding cassette sub-family G member 1.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_4 g15445 g15445.t2 isoform g15445.t2 5473703 5489183
chr_4 g15445 g15445.t2 exon g15445.t2.exon1 5473703 5473902
chr_4 g15445 g15445.t2 TSS g15445.t2 5473720 5473720
chr_4 g15445 g15445.t2 exon g15445.t2.exon2 5475063 5475535
chr_4 g15445 g15445.t2 TTS g15445.t2 5475302 5475302
chr_4 g15445 g15445.t2 exon g15445.t2.exon3 5483175 5483305
chr_4 g15445 g15445.t2 cds g15445.t2.CDS1 5483242 5483305
chr_4 g15445 g15445.t2 exon g15445.t2.exon4 5484535 5484670
chr_4 g15445 g15445.t2 cds g15445.t2.CDS2 5484535 5484670
chr_4 g15445 g15445.t2 exon g15445.t2.exon5 5486947 5487491
chr_4 g15445 g15445.t2 cds g15445.t2.CDS3 5486947 5487491
chr_4 g15445 g15445.t2 exon g15445.t2.exon6 5487560 5488027
chr_4 g15445 g15445.t2 cds g15445.t2.CDS4 5487560 5488027
chr_4 g15445 g15445.t2 exon g15445.t2.exon7 5488080 5488336
chr_4 g15445 g15445.t2 cds g15445.t2.CDS5 5488080 5488336
chr_4 g15445 g15445.t2 exon g15445.t2.exon8 5488437 5489183
chr_4 g15445 g15445.t2 cds g15445.t2.CDS6 5488437 5488778

Sequences

>g15445.t2 Gene=g15445 Length=2957
ACTCAACTCAACTGCTTCAGTTGACAGATAATCGTGATCGGCGCAAGACGCAAAATTTTA
TTATTAAACTTCCGCTTTCATCAGCATGTGCATAAAAGAGAGCAGAAAATCACTGTTTGT
AGTTTTTTGTGTGTAATGAAAGAAAGTGTTTTGTGTATGAAAAAAAATAAAGAAATATTG
TGAGAAAAAAATTGAGCAAATTTAACTTTGATTGATCATCATAAAACCAAAAAACCTTGA
ACTTAGTCCACTTTTCAATCACTCAATGCAATAGCAACAACAGACATAATAGAATCTGAG
TCAAGATTGATAGAAAGTTTTACATAGTGACTGCTAAATGCATAAAATACAAACAATTGA
TAAGAACTAAAAATCTCATATTGCAAGCTATAAAAAATTACTCACGATTTGGACTTTGAA
ATTGTAAAAAGAAAGGAAATAAAAAAACATTTGTGAATTAATTGTGAAAAAAAAAAAATT
CAATTGTCGTTAAATAAAATACAAGCAAATTTGAATAATTTCAATAAAAATTTAATTCAG
TGTGAATTGTGATTGTAATGTAGGAAAAAGAACAAAGTAAATGTGTCATTGATTTGAAAT
TTAAATATTAAACAAGAAAGAGAATTTAAATTAAATTAAAAGTTCAACTGCAAGCGTAAA
TTTTGAAATAAAGCCAAACATAAAAGATAATATCAATAGCATTTTTCTTGATGTGATAAA
AAAATTCCAATCATAACAAAATGTCAACAAAAACAGTTAGTTTCGAAGATGTAATCTATG
AGGTACAAACGAAACGCAATTTCACAAGCAATTCATCCGTTCAAAAACAACAATTGCTTA
AAGGTGTTTCTGGAATTTTTAGACATGGTCAGCTTTCTGTAATCATGGGACCATCAGGAG
CTGGCAAAAGTAGTTTACTAAATGCTCTTTCTGGTTATAGAACAGAAGGCGTTTCAGGAA
CAATTTTGTTAAACCGTAAAACCTCATGTTATATTCAACAAGAAGACTATCACCATACAC
TGATCACTGTCAATGAAATGATGATGATGGCATGTCGATTAAAGCTCAAAAATTCAGTTT
CAACTGACTATAAAAAGCAAATTGATGAAATTCTTGCTGGTCTTAATTTAAGTCACAGAA
AATCATCAACAGCAAAGACTTTAAGTGGTGGCGAAAAAAAGCGACTTTCAATTGCACTCG
AATTGGTCACAAATCCCCAAATTATGTTCCTTGACGAGCCTACAAGTGGACTTGATGAAG
TAACAGCATCAGCGTGTATAAGACTGTTAAGACAATTGGCACATGAAGATAGAACAATAA
TTTGCACAATTCATCAACCATCAGCTGCAACCTTTGATTTATTCGATAATATTTACTTGC
TTGCTCAAGGACAATGCGTTTATTCCGGTTCACCAAGAGTTCTTATTCCATTTTTATTGA
ATCAGAATTATACATGTCCTAAGTACAATAATCCTGCTGATTATATAATTGAACTTTGCG
ACACAGAACCAGAAGTGATTCCACATTTTTCATCTCATTTTCTGAATGGCAAAATTCAAT
GTCTTCCAACAAATTCTTCATCAAATGATGCCTCAATTTGTGAATACCAAATGAAGCATT
CAATTAATACTCTACAAATGGAAATTCACAGACCAAAAGAAAGCACAATTATGCAAAAAA
TGAAACAACTTTCAAAATTCTTCAAAAGTGAATATGCTTTGTCAAGTCTTCAACAATTTC
TTGTACTTTTTAATATGATGATGACAAAAATTATGAGAAATCGTGTCGTGCTGTGGATTC
AATTATTCCATCATCTTGGTTGTGGATTTTTTATTGGTCTAATATTTTTAAATTCTGCAA
ATGATGGAATGAGAATGTTTGATCATCTAAAGTTCTGCATGGGTTGTGTCTTTTTTGTTG
TTTATACACAAATTATGGTGCCAATTTTAAGCTATCCATCAGAACTAAGAGTCGTTAAAA
AAGAATGTTTCAACAGATGGTATGGACTGACACCTTACTATCTTGCACTTACTTTTTCAC
GTTTACCACTGCAAATTTTCTTCAATTTAATCTTCTCATCGATTGTGTACTTTTTGAGTG
GTCTGCCAATGGAACCATGGAGATTTTTCCTTTTCGCACTTATTGGAGTTGTTGTTTCTA
TTGTTGCTGAAGGATTGGGTTTGGCTATTGGTGCTACTTTTAATGTCACGAATGGTAGCG
CAGTTGGACCAGCACTCATGGCACCATTCCTTGGACTAGCAATTTATGGTTTCGATTTTG
CTGCCGATGTTCCAATTTTTATGTATGCACTCATGAAATTTTCATTCATACGTGGTGGCG
TTGTTTCTTTAGTTTTGACAGTTTTTGGCTTCAATCGTGAAAAACTTGAATGCAGTGATG
TTTATTGCCATTTTGATGATCCAAAAGTACTTTTAAGATATTTAAGAATTGAAAATGTTT
CATTGTTCACTGAAATTAGTGTTCTTATTGGTTTAATGATTGCTTTTAGAGCTTTATTTT
ATTTAAGTTTAAGAAAAAGATTTTATAAGTAAAATTATCAGAAATATTATTGGAAGGAAA
AATTTATAAACAGGAAATGGAAATTTTTTTAGTTCTTATAATTTAACTCTCTTTTTCAAG
ACTTATGAATCTCTTTGTAAATTTAAGTTTTGATTAAAAAATATCAAAAAAATCAATTTT
TTTAGAATATTTCGAAATTTTTCTAAAAGTTTTTGTTTTAACGACGAAGCAGAAAGAAAT
ACAAAAATAATCAAAAGAAAATTTTTTCATGCCTTGAGTATTTTATTAAAAAAGTATGAA
AAATAAAATTTGATAAATATAATCTCATTAAAAATTATTTGAAACATAAATAGCAAATAG
TTTTAATGTTTTGTAAATTTCTTAATTATTTATTGCATTATTTCCAAAATAAAGAACTCA
TGATTAAAATTATTGAA

>g15445.t2 Gene=g15445 Length=603
MSTKTVSFEDVIYEVQTKRNFTSNSSVQKQQLLKGVSGIFRHGQLSVIMGPSGAGKSSLL
NALSGYRTEGVSGTILLNRKTSCYIQQEDYHHTLITVNEMMMMACRLKLKNSVSTDYKKQ
IDEILAGLNLSHRKSSTAKTLSGGEKKRLSIALELVTNPQIMFLDEPTSGLDEVTASACI
RLLRQLAHEDRTIICTIHQPSAATFDLFDNIYLLAQGQCVYSGSPRVLIPFLLNQNYTCP
KYNNPADYIIELCDTEPEVIPHFSSHFLNGKIQCLPTNSSSNDASICEYQMKHSINTLQM
EIHRPKESTIMQKMKQLSKFFKSEYALSSLQQFLVLFNMMMTKIMRNRVVLWIQLFHHLG
CGFFIGLIFLNSANDGMRMFDHLKFCMGCVFFVVYTQIMVPILSYPSELRVVKKECFNRW
YGLTPYYLALTFSRLPLQIFFNLIFSSIVYFLSGLPMEPWRFFLFALIGVVVSIVAEGLG
LAIGATFNVTNGSAVGPALMAPFLGLAIYGFDFAADVPIFMYALMKFSFIRGGVVSLVLT
VFGFNREKLECSDVYCHFDDPKVLLRYLRIENVSLFTEISVLIGLMIAFRALFYLSLRKR
FYK

Protein features from InterProScan

Transcript Database ID Name Start End E.value
25 g15445.t2 CDD cd03213 ABCG_EPDR 5 223 2.57335E-72
7 g15445.t2 Gene3D G3DSA:3.40.50.300 - 19 232 1.5E-51
4 g15445.t2 PANTHER PTHR48041:SF78 ABC TRANSPORTER EXPRESSED IN TRACHEA, ISOFORM A-RELATED 6 599 3.7E-155
5 g15445.t2 PANTHER PTHR48041 ABC TRANSPORTER G FAMILY MEMBER 28 6 599 3.7E-155
3 g15445.t2 Pfam PF00005 ABC transporter 33 169 9.8E-25
1 g15445.t2 Pfam PF19055 ABC-2 type transporter 198 321 6.0E-6
2 g15445.t2 Pfam PF01061 ABC-2 type transporter 331 536 1.3E-20
12 g15445.t2 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 1 324 -
19 g15445.t2 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 325 345 -
15 g15445.t2 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 346 350 -
17 g15445.t2 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 351 373 -
8 g15445.t2 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 374 384 -
21 g15445.t2 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 385 406 -
13 g15445.t2 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 407 425 -
18 g15445.t2 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 426 452 -
10 g15445.t2 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 453 463 -
23 g15445.t2 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 464 487 -
16 g15445.t2 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 488 492 -
24 g15445.t2 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 493 511 -
9 g15445.t2 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 512 522 -
22 g15445.t2 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 523 544 -
14 g15445.t2 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 545 574 -
20 g15445.t2 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 575 597 -
11 g15445.t2 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 598 603 -
33 g15445.t2 ProSitePatterns PS00211 ABC transporters family signature. 141 155 -
35 g15445.t2 ProSiteProfiles PS50893 ATP-binding cassette, ABC transporter-type domain profile. 6 241 17.901
34 g15445.t2 SMART SM00382 AAA_5 42 217 4.6E-8
6 g15445.t2 SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases 28 232 3.55E-45
29 g15445.t2 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 349 371 -
31 g15445.t2 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 383 405 -
28 g15445.t2 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 435 454 -
26 g15445.t2 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 461 483 -
32 g15445.t2 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 498 520 -
30 g15445.t2 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 527 544 -
27 g15445.t2 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 575 597 -

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0016020 membrane CC
GO:0005524 ATP binding MF
GO:0042626 ATPase-coupled transmembrane transporter activity MF
GO:0016887 ATP hydrolysis activity MF

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values