General information for g15452.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as ATP-binding cassette sub-family G member 1.
Parent gene
- The parent gene g15452 is located on chr_4: 5502518..5504332 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g15452 | g15452.t1 | TTS | g15452.t1 | 5501423 | 5501423 |
| chr_4 | g15452 | g15452.t1 | isoform | g15452.t1 | 5501484 | 5504332 |
| chr_4 | g15452 | g15452.t1 | exon | g15452.t1.exon1 | 5501484 | 5501819 |
| chr_4 | g15452 | g15452.t1 | cds | g15452.t1.CDS1 | 5501484 | 5501819 |
| chr_4 | g15452 | g15452.t1 | exon | g15452.t1.exon2 | 5501877 | 5502133 |
| chr_4 | g15452 | g15452.t1 | cds | g15452.t1.CDS2 | 5501877 | 5502133 |
| chr_4 | g15452 | g15452.t1 | exon | g15452.t1.exon3 | 5502955 | 5503569 |
| chr_4 | g15452 | g15452.t1 | cds | g15452.t1.CDS3 | 5502955 | 5503569 |
| chr_4 | g15452 | g15452.t1 | exon | g15452.t1.exon4 | 5503807 | 5504332 |
| chr_4 | g15452 | g15452.t1 | cds | g15452.t1.CDS4 | 5503807 | 5504332 |
| chr_4 | g15452 | g15452.t1 | TSS | g15452.t1 | 5504344 | 5504344 |
Sequences
>g15452.t1 Gene=g15452 Length=1734
ATGACCGAACATATAAGTCTTCGTTTCGCGAACGTCTCTTGCCATGTGCATACAATTTCA
TTTAGGCATAGATTAAAGAAAATTCTTAAGAATGTTTCGGGTAATTTTAATGGTGGTGAA
TTGACAGCTATTGTTGGTCCAAGTGGAAGTGGAAAAAGTACACTTTTAGATTGTCTTTCG
GGTTTTAGAAGGACAAATGTTAGTGGAAAATTTATCGTCGATGGAAATGAAATTTCAATC
GATGATATTCGACAAATGTCGTCATATGTTATGCAAGATCAAAGTCTCCATATACATCTT
ACTGTGCGCGAAATTATGGCGCTGTCCTTGAACTTGAGAGATAAACAAAATCTGAGTGAT
GCGGCAAAAAAAAATAAAATTTTTAATGTTTTTGAAACACTCGGCATTGAAAGAAAATGT
GAGACTGTAATGACGGAATTAAGTGGTGGCGAAAGAAAAAGAGTTCAAATTGCTATTGAA
TTGGTCAACGATCCGAAAATTTTATTTGTTGATGAAGCTACTACAGGTCTCGACTGTGTA
GCATCAACACGCTGCATTGAATATCTCAAAAAACTCGCACTCGAAGGACGTACTATAATT
TGTACAATTCATCAACCTTCAGCATCGATTCTCAAATTATTTGATCAAATTTATGCAATA
GCAAATGGAAGTTGCATTTATCAAGGCTCATCGACAAAACTTTTGGAATTTTTAAATGAC
ATTGAACTTCCTTGTCCATCAACTTACAATCCAATTGATTTTTTACTTGAAATTGCTAAT
GATTGTTATGGAGAACAAAGTGAAAAATTGATACAAAAAATTGAAAATGGGAAAAATTTT
GATTATTGCAATGTGAAAGAAAAATATGAAAATTTTATTTTATCAGAAGTGAATTATCAT
CAAAGTTCATCATATTCAAAACAAGTTTATTATTTACTAAAAAGAACTTTTCTTACAACG
TCTCGTGACATGACAATTTTTACTTTTCGATATTTCTTTCATTTAATTCTTGGACTTACT
TTTGGGTTAATGTATCATGACATGGGAAATCGAGGAGAATATATGCTGAATAATTACAAA
TATTTGGTGCTCTCTGTGGTTATTTTGGTTTATACTTCTTATTATTCTATTTATTTTCAA
TTTCTTCACGAATTTTCAATAGTAAAAAGAGAATATTTCAATGGCTGGTATTCAACAGAA
GCATACTACACTGCTTTAATACTTTTTGACGTTCCAATGACTCTAATATGTTGTACAACT
TATGTTTCAATAACTTATTGGTTAACAAATCAACCAGCAGAATTTTATCGATATATTTTA
TTCTTAAGTTTCATCATTTTGATGTCATTTGCATCACAATCACTTGGTGTTATGTTTTCA
TCAGTTTTAGACATTAAGACGGCTACAACATTTAGTTTTATGTTTCTTCTTCCATTCATT
GTCTTATCAGGAATTTTAATAGTGACAAGTCACACGCCTGAATTTTTTAAATTTTTCTTC
GATTTTAATTTCCTTGACAGTACTCTAAAAGGAGTTTTGAATTCAGTTTTGGGTCTTGGT
AGGAGAAAAGCAGAATGTGATGATTTATATTGTCATTTGGTAGAACCAGGGAAACTTTTA
AGTGATTTTGGTGCAGTGATTGATATTTCAAGAGCATTTAAAGTTATTTTGATTTATATT
GTGATTTGTCAAATTATTTCTTATTTAATTATTAGATATCGTTTAAGAAAATGA
>g15452.t1 Gene=g15452 Length=577
MTEHISLRFANVSCHVHTISFRHRLKKILKNVSGNFNGGELTAIVGPSGSGKSTLLDCLS
GFRRTNVSGKFIVDGNEISIDDIRQMSSYVMQDQSLHIHLTVREIMALSLNLRDKQNLSD
AAKKNKIFNVFETLGIERKCETVMTELSGGERKRVQIAIELVNDPKILFVDEATTGLDCV
ASTRCIEYLKKLALEGRTIICTIHQPSASILKLFDQIYAIANGSCIYQGSSTKLLEFLND
IELPCPSTYNPIDFLLEIANDCYGEQSEKLIQKIENGKNFDYCNVKEKYENFILSEVNYH
QSSSYSKQVYYLLKRTFLTTSRDMTIFTFRYFFHLILGLTFGLMYHDMGNRGEYMLNNYK
YLVLSVVILVYTSYYSIYFQFLHEFSIVKREYFNGWYSTEAYYTALILFDVPMTLICCTT
YVSITYWLTNQPAEFYRYILFLSFIILMSFASQSLGVMFSSVLDIKTATTFSFMFLLPFI
VLSGILIVTSHTPEFFKFFFDFNFLDSTLKGVLNSVLGLGRRKAECDDLYCHLVEPGKLL
SDFGAVIDISRAFKVILIYIVICQIISYLIIRYRLRK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g15452.t1 | Gene3D | G3DSA:3.40.50.300 | - | 14 | 242 | 1.8E-57 |
| 4 | g15452.t1 | PANTHER | PTHR48041:SF78 | ABC TRANSPORTER EXPRESSED IN TRACHEA, ISOFORM A-RELATED | 5 | 573 | 3.9E-162 |
| 5 | g15452.t1 | PANTHER | PTHR48041 | ABC TRANSPORTER G FAMILY MEMBER 28 | 5 | 573 | 3.9E-162 |
| 3 | g15452.t1 | Pfam | PF00005 | ABC transporter | 29 | 174 | 9.1E-27 |
| 1 | g15452.t1 | Pfam | PF19055 | ABC-2 type transporter | 204 | 263 | 2.4E-5 |
| 2 | g15452.t1 | Pfam | PF01061 | ABC-2 type transporter | 308 | 515 | 1.7E-29 |
| 10 | g15452.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 1 | 323 | - |
| 18 | g15452.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 324 | 345 | - |
| 13 | g15452.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 346 | 360 | - |
| 17 | g15452.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 361 | 381 | - |
| 9 | g15452.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 382 | 401 | - |
| 20 | g15452.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 402 | 429 | - |
| 12 | g15452.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 430 | 434 | - |
| 16 | g15452.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 435 | 459 | - |
| 8 | g15452.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 460 | 470 | - |
| 19 | g15452.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 471 | 489 | - |
| 14 | g15452.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 490 | 551 | - |
| 15 | g15452.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 552 | 571 | - |
| 11 | g15452.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 572 | 577 | - |
| 27 | g15452.t1 | ProSitePatterns | PS00211 | ABC transporters family signature. | 147 | 161 | - |
| 29 | g15452.t1 | ProSiteProfiles | PS50893 | ATP-binding cassette, ABC transporter-type domain profile. | 7 | 247 | 19.635 |
| 28 | g15452.t1 | SMART | SM00382 | AAA_5 | 38 | 224 | 9.6E-14 |
| 6 | g15452.t1 | SUPERFAMILY | SSF52540 | P-loop containing nucleoside triphosphate hydrolases | 17 | 242 | 1.68E-48 |
| 26 | g15452.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 326 | 345 | - |
| 23 | g15452.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 360 | 382 | - |
| 25 | g15452.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 403 | 425 | - |
| 21 | g15452.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 435 | 457 | - |
| 24 | g15452.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 470 | 492 | - |
| 22 | g15452.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 549 | 571 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016020 | membrane | CC |
| GO:0005524 | ATP binding | MF |
| GO:0042626 | ATPase-coupled transmembrane transporter activity | MF |
| GO:0016887 | ATP hydrolysis activity | MF |
KEGG
Orthology
- This transcript has been annotated with K08712 (ATP-binding cassette, subfamily G (WHITE), member 2, SNQ2)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed