General information for g15452.t16
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as ATP-binding cassette sub-family G member 4.
Parent gene
- The parent gene g15452 is located on chr_4: 5502518..5504332 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g15452 | g15452.t16 | isoform | g15452.t16 | 5502518 | 5504332 |
| chr_4 | g15452 | g15452.t16 | exon | g15452.t16.exon1 | 5502518 | 5503569 |
| chr_4 | g15452 | g15452.t16 | cds | g15452.t16.CDS1 | 5502947 | 5503569 |
| chr_4 | g15452 | g15452.t16 | exon | g15452.t16.exon2 | 5503807 | 5504332 |
| chr_4 | g15452 | g15452.t16 | cds | g15452.t16.CDS2 | 5503807 | 5504332 |
| chr_4 | g15452 | g15452.t16 | TSS | g15452.t16 | 5504344 | 5504344 |
| chr_4 | g15452 | g15452.t16 | TTS | g15452.t16 | NA | NA |
Sequences
>g15452.t16 Gene=g15452 Length=1578
ATGACCGAACATATAAGTCTTCGTTTCGCGAACGTCTCTTGCCATGTGCATACAATTTCA
TTTAGGCATAGATTAAAGAAAATTCTTAAGAATGTTTCGGGTAATTTTAATGGTGGTGAA
TTGACAGCTATTGTTGGTCCAAGTGGAAGTGGAAAAAGTACACTTTTAGATTGTCTTTCG
GGTTTTAGAAGGACAAATGTTAGTGGAAAATTTATCGTCGATGGAAATGAAATTTCAATC
GATGATATTCGACAAATGTCGTCATATGTTATGCAAGATCAAAGTCTCCATATACATCTT
ACTGTGCGCGAAATTATGGCGCTGTCCTTGAACTTGAGAGATAAACAAAATCTGAGTGAT
GCGGCAAAAAAAAATAAAATTTTTAATGTTTTTGAAACACTCGGCATTGAAAGAAAATGT
GAGACTGTAATGACGGAATTAAGTGGTGGCGAAAGAAAAAGAGTTCAAATTGCTATTGAA
TTGGTCAACGATCCGAAAATTTTATTTGTTGATGAAGCTACTACAGGTCTCGACTGTGTA
GCATCAACACGCTGCATTGAATATCTCAAAAAACTCGCACTCGAAGGACGTACTATAATT
TGTACAATTCATCAACCTTCAGCATCGATTCTCAAATTATTTGATCAAATTTATGCAATA
GCAAATGGAAGTTGCATTTATCAAGGCTCATCGACAAAACTTTTGGAATTTTTAAATGAC
ATTGAACTTCCTTGTCCATCAACTTACAATCCAATTGATTTTTTACTTGAAATTGCTAAT
GATTGTTATGGAGAACAAAGTGAAAAATTGATACAAAAAATTGAAAATGGGAAAAATTTT
GATTATTGCAATGTGAAAGAAAAATATGAAAATTTTATTTTATCAGAAGTGAATTATCAT
CAAAGTTCATCATATTCAAAACAAGTTTATTATTTACTAAAAAGAACTTTTCTTACAACG
TCTCGTGACATGACAATTTTTACTTTTCGATATTTCTTTCATTTAATTCTTGGACTTACT
TTTGGGTTAATGTATCATGACATGGGAAATCGAGGAGAATATATGCTGAATAATTACAAA
TATTTGGTGCTCTCTGTGGTTATTTTGGTTTATACTTCTTATTATTCTATTTATTTTCAA
TGTAAGTAGATGTTTTATTTTTAAAATAATGGAAAATTTTATTATTTATGGATCTGACTC
AGATCATCTAAATAATTTTCTTATCTACAAATTAATTCTATAATTAATAACTTCTAATCG
AAATTAAAAATCAACAAAAATTCATTTACCACTGAATATTGTTTAAAATTTAAAATAGCT
AAGGTCAATAGCTTTTCAAAAAAATACATTGAAATTTCGCAAAAAAAATTTAAAGTGGTT
AATAAATAATTTTTAAGTAGATACTCAAATATTTGAGGTTTGCATTAAATAGCAAAAATC
ATTTTAAAAAATTTCTGAAGATGTTGAAGAATCTGTTTAAACTTGAAAACTTTTTCTATT
GATTTTAATAGAAGCTGTTTACATAATTTGGGGTCTCAATAAATATATTTTGTTATCGAA
CTGTGACACAAACAAAAT
>g15452.t16 Gene=g15452 Length=382
MTEHISLRFANVSCHVHTISFRHRLKKILKNVSGNFNGGELTAIVGPSGSGKSTLLDCLS
GFRRTNVSGKFIVDGNEISIDDIRQMSSYVMQDQSLHIHLTVREIMALSLNLRDKQNLSD
AAKKNKIFNVFETLGIERKCETVMTELSGGERKRVQIAIELVNDPKILFVDEATTGLDCV
ASTRCIEYLKKLALEGRTIICTIHQPSASILKLFDQIYAIANGSCIYQGSSTKLLEFLND
IELPCPSTYNPIDFLLEIANDCYGEQSEKLIQKIENGKNFDYCNVKEKYENFILSEVNYH
QSSSYSKQVYYLLKRTFLTTSRDMTIFTFRYFFHLILGLTFGLMYHDMGNRGEYMLNNYK
YLVLSVVILVYTSYYSIYFQCK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 12 | g15452.t16 | CDD | cd03213 | ABCG_EPDR | 4 | 229 | 3.88347E-72 |
| 6 | g15452.t16 | Gene3D | G3DSA:3.40.50.300 | - | 4 | 242 | 6.8E-58 |
| 3 | g15452.t16 | PANTHER | PTHR48041:SF78 | ABC TRANSPORTER EXPRESSED IN TRACHEA, ISOFORM A-RELATED | 5 | 376 | 1.7E-115 |
| 4 | g15452.t16 | PANTHER | PTHR48041 | ABC TRANSPORTER G FAMILY MEMBER 28 | 5 | 376 | 1.7E-115 |
| 2 | g15452.t16 | Pfam | PF00005 | ABC transporter | 29 | 174 | 4.0E-27 |
| 1 | g15452.t16 | Pfam | PF19055 | ABC-2 type transporter | 204 | 263 | 1.4E-5 |
| 8 | g15452.t16 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 1 | 323 | - |
| 11 | g15452.t16 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 324 | 346 | - |
| 9 | g15452.t16 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 347 | 357 | - |
| 10 | g15452.t16 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 358 | 377 | - |
| 7 | g15452.t16 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 378 | 382 | - |
| 15 | g15452.t16 | ProSitePatterns | PS00211 | ABC transporters family signature. | 147 | 161 | - |
| 17 | g15452.t16 | ProSiteProfiles | PS50893 | ATP-binding cassette, ABC transporter-type domain profile. | 7 | 247 | 19.635 |
| 16 | g15452.t16 | SMART | SM00382 | AAA_5 | 38 | 224 | 9.6E-14 |
| 5 | g15452.t16 | SUPERFAMILY | SSF52540 | P-loop containing nucleoside triphosphate hydrolases | 17 | 244 | 5.32E-49 |
| 13 | g15452.t16 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 327 | 346 | - |
| 14 | g15452.t16 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 361 | 379 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005524 | ATP binding | MF |
| GO:0042626 | ATPase-coupled transmembrane transporter activity | MF |
| GO:0016887 | ATP hydrolysis activity | MF |
KEGG
Orthology
- This transcript has been annotated with K25285 (iron-siderophore transport system ATP-binding protein [EC:7.2.2.-])
Pathway
This gene does not belong to any pathways.
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed