General information for g15480.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Insulin-like growth factor-binding protein complex acid labile subunit.
Parent gene
- The parent gene g15480 is located on chr_4: 5596676..5597275 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g15480 | g15480.t1 | isoform | g15480.t1 | 5594321 | 5597202 |
| chr_4 | g15480 | g15480.t1 | exon | g15480.t1.exon1 | 5594321 | 5595155 |
| chr_4 | g15480 | g15480.t1 | cds | g15480.t1.CDS1 | 5594321 | 5595155 |
| chr_4 | g15480 | g15480.t1 | exon | g15480.t1.exon2 | 5595258 | 5596680 |
| chr_4 | g15480 | g15480.t1 | cds | g15480.t1.CDS2 | 5595258 | 5596680 |
| chr_4 | g15480 | g15480.t1 | exon | g15480.t1.exon3 | 5596757 | 5597062 |
| chr_4 | g15480 | g15480.t1 | cds | g15480.t1.CDS3 | 5596757 | 5597062 |
| chr_4 | g15480 | g15480.t1 | exon | g15480.t1.exon4 | 5597121 | 5597202 |
| chr_4 | g15480 | g15480.t1 | cds | g15480.t1.CDS4 | 5597121 | 5597202 |
| chr_4 | g15480 | g15480.t1 | TSS | g15480.t1 | NA | NA |
| chr_4 | g15480 | g15480.t1 | TTS | g15480.t1 | NA | NA |
Sequences
>g15480.t1 Gene=g15480 Length=2646
ATGCGACTTTTATTATTGCGTGAATTTATGTTTTTAGTAACCTTAGTGACATTTACATTA
TCAAATTCATTTGATAATTATGACAAATGTTTGACTTCATCACCATGCGGACCTCATTCC
AATTGCCGTAATTTTCCAACTTTTGTTTCCTGCTCATGTCTTGAAGGTTTTATTGGAAGT
CCACCAAATTGTCGTCAACCAGAATGCTTTTATGACACACAATGTCCAAAAGATAAAGCA
TGTTTTGGAGCAACTTGTATTGACGTTTGCATTGCTCAAAAATGCAATGAAAATGCAAAA
TGTGTTGTGAAAAATCATAAACCAATTTGTGAATGTCAAATTGGATTCATCGAGAATGAA
AATGATGATGAATGTGAAGAAAATACCAATGTCATTGATGGTTCTTTAAGAATTGATGAT
TTCTTTCTAGTTCATGAAGAATTTAAAGATTTTTTGAAAAATCGTTTTAAGAAAAATTTC
ACAATATTTATGGTTGCAAATGAAACAAAAATAAAAAAAGAAAATTTTGAAATTTCTCTG
AAGCATAAAAATAATGAAGTTCATGCATTGACAATACTTAACTTTTTTATTAATGAAATA
GGATGGTCTTCTAACCAAAATAACATAAAATATTTACCAATAAAAGTTGGAGAAATTTTT
CAAAATTTATTTGCTTATGCAGTTTTAAGTTTTAAAATACCTGAAATTAAGAAAAGTAAT
TTTAAAAACCTGACAAAATTAGAATTCCTGAATTTACAAAATAATGAAATTGTAAATATT
TCTAATGACGCTTTTGAAGATCTTTTTGAATTGAGAATTTTGTCACTTCGAGGAAATCAT
TTGGAAAATATAAATAGGAAATGGTTTAAAAACACAAAAAATCTTCAACTACTTGACCTA
AGCCATAACATAATACATGCAATAAAAGATCCAAAAACTTTTAAAGATCTGAAAAATCTC
AAAAAGCTTAGTCTGGAGGGAAACAGATTAAAATTTTTAAATTCAAAAATTTTCATAAAT
TTGCCAAATTTAAAAACTCTCAATATGCAATCAAATGACCTTAAAAATTTTAGAATTGAA
ATTTCTCAAAATTTGCCTTTGCTTGAAAATCTCTATCTTGGATCGAATAAATTTACCAAC
TTACCACATGAATTTCTTCAAAAAACTAAAAATTTGAAAATATTTAATGTGTTTGGAAAT
ATTCAAATCACTACTGAAACTTTTAAAAACTTGTATCAACTCGAAGAACTACAATTGGTT
AACGTTGGATTACAAACTCTTCCAAGTGGAATTTTTAAAGATACAAATAATCTTAAAAAG
TTAGATTTATCGTCAAATTCATTGAGAAATATTTCTAAAGATGACATTGGCCATTTGACG
CAACTTGAAGAACTTGATTTGACAAGAAATGAAATTCAATCAACCGAAAATGGAATTTTT
GATAAATTTTTTAACCTCAAAAAACTTAAACTGGAGGAATCTGGGATCAAAGCGCTTGGT
GAAAATATTTTTAAAAGTTTGCATAAACTTGAACTTATAGAATTGAGATATTTGGAACTT
GAAAAATTGCCAACAAAAATCTTTCAAAATAACAAAAAACTTCAAACAATTTTCTTAAGT
AATAACAAAATTTCTTCATTAAATGTCGAAATGTTTGATGGATTAACTGGAATCATAAAT
CTTGACCTTGGAAATAATGAATTGACCACTTTGGATAAATATATTTTCGCATCATTGGAT
AATTTGAAAGGATTAAGACTTTCATGTAATGATCTGAAAGATATTTCTGAGGACATTTTT
GAAAATTTAAGATCACTAGAAATTCTCAACATGGAAAACTGCCATTTGATGACTTTGAAA
CCAAAACTATTTGAAAAGACGATAAAATTGAAGAAATTGAATCTTTATCAACAAGGTAAT
CTGACTTCAATTCCAATTGAAGCTTTTTCAACACTTAGAGAACTTGAAAGTCTTGACTTA
TCTGGAAATGAGTTTAAAAGCCTTGACAATGATGTCTTTAAAAATTTAATCAATTTGAAA
AATTTATACTTGAATTATGGCAAATTGGAATCATTGGAAGAAGGAATTTTTAGAAATTTA
AAAACAATAGAAACAATTCAATTAGGTGGAAATTTAATTGCAGAAATTCCTCAAAATTTA
TTTAAAAATAATGAAAATCTTTTTGTACTTTATCTTAGTGACAATATTTTGTATTTTTTA
CATCCTGAAACATTCAATGGACTGAGAAAATTAAAATATCTCAATCTTCACAATAACAGA
CTTAATTCTTTGGATCCTAATTTATTTTCTGCAAATTTGAATTTAAAAACAATTGAATTG
TCTCAAAATGAAATTCAGTACATTCCTAAAGAAATTTTTAAGAATTTAATAAATCTCGAA
AATATTTCTCTTGAAAAAAATCAACTTTATGGCTTACCAGAAAATATTTTTGAAAATAAT
CCAAATTTAGCTGTTGTTAAACTCAGTCGTAATCAAATATCAACAATTATATCAGAATTA
TTTGAAGAAAAATATGAATTAAACTTTGTTGACTTAGAATATAATCGTTGCATTGATAAA
ACATATTTATATTTGACACAAGAGAAGATTGAAGAATTGATCAATGATGTTAGAAGCAAA
TGTTAA
>g15480.t1 Gene=g15480 Length=881
MRLLLLREFMFLVTLVTFTLSNSFDNYDKCLTSSPCGPHSNCRNFPTFVSCSCLEGFIGS
PPNCRQPECFYDTQCPKDKACFGATCIDVCIAQKCNENAKCVVKNHKPICECQIGFIENE
NDDECEENTNVIDGSLRIDDFFLVHEEFKDFLKNRFKKNFTIFMVANETKIKKENFEISL
KHKNNEVHALTILNFFINEIGWSSNQNNIKYLPIKVGEIFQNLFAYAVLSFKIPEIKKSN
FKNLTKLEFLNLQNNEIVNISNDAFEDLFELRILSLRGNHLENINRKWFKNTKNLQLLDL
SHNIIHAIKDPKTFKDLKNLKKLSLEGNRLKFLNSKIFINLPNLKTLNMQSNDLKNFRIE
ISQNLPLLENLYLGSNKFTNLPHEFLQKTKNLKIFNVFGNIQITTETFKNLYQLEELQLV
NVGLQTLPSGIFKDTNNLKKLDLSSNSLRNISKDDIGHLTQLEELDLTRNEIQSTENGIF
DKFFNLKKLKLEESGIKALGENIFKSLHKLELIELRYLELEKLPTKIFQNNKKLQTIFLS
NNKISSLNVEMFDGLTGIINLDLGNNELTTLDKYIFASLDNLKGLRLSCNDLKDISEDIF
ENLRSLEILNMENCHLMTLKPKLFEKTIKLKKLNLYQQGNLTSIPIEAFSTLRELESLDL
SGNEFKSLDNDVFKNLINLKNLYLNYGKLESLEEGIFRNLKTIETIQLGGNLIAEIPQNL
FKNNENLFVLYLSDNILYFLHPETFNGLRKLKYLNLHNNRLNSLDPNLFSANLNLKTIEL
SQNEIQYIPKEIFKNLINLENISLEKNQLYGLPENIFENNPNLAVVKLSRNQISTIISEL
FEEKYELNFVDLEYNRCIDKTYLYLTQEKIEELINDVRSKC
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 27 | g15480.t1 | CDD | cd00054 | EGF_CA | 28 | 64 | 8.29196E-6 |
| 19 | g15480.t1 | Gene3D | G3DSA:3.80.10.10 | Ribonuclease Inhibitor | 201 | 312 | 3.1E-16 |
| 17 | g15480.t1 | Gene3D | G3DSA:3.80.10.10 | Ribonuclease Inhibitor | 313 | 402 | 4.2E-16 |
| 21 | g15480.t1 | Gene3D | G3DSA:3.80.10.10 | Ribonuclease Inhibitor | 403 | 637 | 5.6E-53 |
| 20 | g15480.t1 | Gene3D | G3DSA:3.80.10.10 | Ribonuclease Inhibitor | 638 | 757 | 5.6E-28 |
| 18 | g15480.t1 | Gene3D | G3DSA:3.80.10.10 | Ribonuclease Inhibitor | 758 | 875 | 7.0E-22 |
| 10 | g15480.t1 | PANTHER | PTHR45712 | AGAP008170-PA | 232 | 430 | 3.5E-148 |
| 12 | g15480.t1 | PANTHER | PTHR45712 | AGAP008170-PA | 402 | 635 | 3.5E-148 |
| 9 | g15480.t1 | PANTHER | PTHR45712 | AGAP008170-PA | 521 | 704 | 3.5E-148 |
| 11 | g15480.t1 | PANTHER | PTHR45712 | AGAP008170-PA | 590 | 789 | 3.5E-148 |
| 8 | g15480.t1 | PANTHER | PTHR45712 | AGAP008170-PA | 637 | 855 | 3.5E-148 |
| 6 | g15480.t1 | Pfam | PF13855 | Leucine rich repeat | 235 | 281 | 1.3E-8 |
| 2 | g15480.t1 | Pfam | PF13855 | Leucine rich repeat | 310 | 354 | 6.5E-9 |
| 7 | g15480.t1 | Pfam | PF13855 | Leucine rich repeat | 413 | 472 | 3.9E-13 |
| 5 | g15480.t1 | Pfam | PF13855 | Leucine rich repeat | 560 | 616 | 1.7E-11 |
| 3 | g15480.t1 | Pfam | PF13855 | Leucine rich repeat | 629 | 685 | 6.2E-9 |
| 1 | g15480.t1 | Pfam | PF13855 | Leucine rich repeat | 703 | 761 | 2.4E-12 |
| 4 | g15480.t1 | Pfam | PF13855 | Leucine rich repeat | 798 | 856 | 3.6E-7 |
| 23 | g15480.t1 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 23 | - |
| 24 | g15480.t1 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 10 | - |
| 25 | g15480.t1 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 11 | 18 | - |
| 26 | g15480.t1 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 19 | 23 | - |
| 22 | g15480.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 24 | 881 | - |
| 28 | g15480.t1 | ProSitePatterns | PS01186 | EGF-like domain signature 2. | 51 | 64 | - |
| 29 | g15480.t1 | ProSitePatterns | PS01186 | EGF-like domain signature 2. | 110 | 125 | - |
| 85 | g15480.t1 | ProSiteProfiles | PS50026 | EGF-like domain profile. | 26 | 65 | 12.2 |
| 83 | g15480.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 246 | 267 | 8.02 |
| 81 | g15480.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 270 | 291 | 6.149 |
| 72 | g15480.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 294 | 315 | 7.127 |
| 74 | g15480.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 319 | 340 | 6.418 |
| 77 | g15480.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 343 | 364 | 6.164 |
| 70 | g15480.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 367 | 388 | 6.441 |
| 78 | g15480.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 437 | 460 | 7.335 |
| 68 | g15480.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 461 | 482 | 6.826 |
| 75 | g15480.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 533 | 554 | 6.934 |
| 69 | g15480.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 557 | 578 | 5.818 |
| 64 | g15480.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 581 | 602 | 7.342 |
| 76 | g15480.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 605 | 626 | 5.032 |
| 71 | g15480.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 629 | 651 | 5.202 |
| 80 | g15480.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 654 | 675 | 7.512 |
| 67 | g15480.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 678 | 699 | 6.018 |
| 84 | g15480.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 702 | 723 | 5.202 |
| 79 | g15480.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 726 | 747 | 5.725 |
| 82 | g15480.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 750 | 771 | 7.989 |
| 66 | g15480.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 774 | 795 | 6.934 |
| 65 | g15480.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 798 | 819 | 5.895 |
| 73 | g15480.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 822 | 843 | 5.964 |
| 62 | g15480.t1 | SMART | SM00181 | egf_5 | 29 | 65 | 1.9 |
| 63 | g15480.t1 | SMART | SM00181 | egf_5 | 89 | 126 | 15.0 |
| 47 | g15480.t1 | SMART | SM00369 | LRR_typ_2 | 244 | 267 | 0.014 |
| 58 | g15480.t1 | SMART | SM00365 | LRR_sd22_2 | 244 | 265 | 52.0 |
| 44 | g15480.t1 | SMART | SM00369 | LRR_typ_2 | 268 | 291 | 4.9 |
| 56 | g15480.t1 | SMART | SM00365 | LRR_sd22_2 | 268 | 286 | 570.0 |
| 49 | g15480.t1 | SMART | SM00369 | LRR_typ_2 | 292 | 316 | 260.0 |
| 59 | g15480.t1 | SMART | SM00365 | LRR_sd22_2 | 292 | 313 | 110.0 |
| 48 | g15480.t1 | SMART | SM00369 | LRR_typ_2 | 317 | 340 | 0.48 |
| 60 | g15480.t1 | SMART | SM00365 | LRR_sd22_2 | 317 | 343 | 28.0 |
| 38 | g15480.t1 | SMART | SM00369 | LRR_typ_2 | 341 | 364 | 10.0 |
| 39 | g15480.t1 | SMART | SM00369 | LRR_typ_2 | 365 | 388 | 0.99 |
| 42 | g15480.t1 | SMART | SM00369 | LRR_typ_2 | 411 | 434 | 8.6 |
| 61 | g15480.t1 | SMART | SM00365 | LRR_sd22_2 | 435 | 453 | 180.0 |
| 32 | g15480.t1 | SMART | SM00369 | LRR_typ_2 | 437 | 458 | 73.0 |
| 34 | g15480.t1 | SMART | SM00369 | LRR_typ_2 | 459 | 482 | 0.34 |
| 55 | g15480.t1 | SMART | SM00365 | LRR_sd22_2 | 459 | 482 | 59.0 |
| 36 | g15480.t1 | SMART | SM00369 | LRR_typ_2 | 483 | 506 | 130.0 |
| 35 | g15480.t1 | SMART | SM00369 | LRR_typ_2 | 507 | 530 | 67.0 |
| 54 | g15480.t1 | SMART | SM00365 | LRR_sd22_2 | 531 | 557 | 30.0 |
| 45 | g15480.t1 | SMART | SM00369 | LRR_typ_2 | 532 | 554 | 20.0 |
| 52 | g15480.t1 | SMART | SM00369 | LRR_typ_2 | 555 | 578 | 4.9 |
| 30 | g15480.t1 | SMART | SM00369 | LRR_typ_2 | 579 | 602 | 0.39 |
| 50 | g15480.t1 | SMART | SM00369 | LRR_typ_2 | 603 | 626 | 1.1 |
| 51 | g15480.t1 | SMART | SM00369 | LRR_typ_2 | 652 | 675 | 0.003 |
| 57 | g15480.t1 | SMART | SM00365 | LRR_sd22_2 | 652 | 673 | 92.0 |
| 37 | g15480.t1 | SMART | SM00369 | LRR_typ_2 | 676 | 699 | 1.6 |
| 46 | g15480.t1 | SMART | SM00369 | LRR_typ_2 | 700 | 723 | 11.0 |
| 41 | g15480.t1 | SMART | SM00369 | LRR_typ_2 | 725 | 747 | 47.0 |
| 31 | g15480.t1 | SMART | SM00369 | LRR_typ_2 | 748 | 771 | 0.0026 |
| 53 | g15480.t1 | SMART | SM00365 | LRR_sd22_2 | 772 | 801 | 62.0 |
| 33 | g15480.t1 | SMART | SM00369 | LRR_typ_2 | 774 | 795 | 24.0 |
| 43 | g15480.t1 | SMART | SM00369 | LRR_typ_2 | 796 | 819 | 0.26 |
| 40 | g15480.t1 | SMART | SM00369 | LRR_typ_2 | 821 | 843 | 150.0 |
| 14 | g15480.t1 | SUPERFAMILY | SSF52047 | RNI-like | 239 | 637 | 1.02E-45 |
| 13 | g15480.t1 | SUPERFAMILY | SSF52058 | L domain-like | 639 | 857 | 1.45E-42 |
| 16 | g15480.t1 | SignalP_EUK | SignalP-noTM | SignalP-noTM | 1 | 21 | - |
| 15 | g15480.t1 | SignalP_GRAM_POSITIVE | SignalP-TM | SignalP-TM | 1 | 12 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005515 | protein binding | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
