General information for g15492.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Glycerol kinase 3.
Parent gene
- The parent gene g15492 is located on chr_4: 5626132..5627966 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g15492 | g15492.t1 | TTS | g15492.t1 | 5624967 | 5624967 |
| chr_4 | g15492 | g15492.t1 | isoform | g15492.t1 | 5625025 | 5627081 |
| chr_4 | g15492 | g15492.t1 | exon | g15492.t1.exon1 | 5625025 | 5625354 |
| chr_4 | g15492 | g15492.t1 | cds | g15492.t1.CDS1 | 5625025 | 5625354 |
| chr_4 | g15492 | g15492.t1 | exon | g15492.t1.exon2 | 5625433 | 5626586 |
| chr_4 | g15492 | g15492.t1 | cds | g15492.t1.CDS2 | 5625433 | 5626586 |
| chr_4 | g15492 | g15492.t1 | exon | g15492.t1.exon3 | 5627036 | 5627081 |
| chr_4 | g15492 | g15492.t1 | cds | g15492.t1.CDS3 | 5627036 | 5627081 |
| chr_4 | g15492 | g15492.t1 | TSS | g15492.t1 | 5627232 | 5627232 |
Sequences
>g15492.t1 Gene=g15492 Length=1530
ATGAGCAGCAGTAAATTTGGAAATTTAATTGGAGCAATTGATGAAGGAACAAGTTCAGCA
CGTTTCATAATTTTCAAAGCTGAAACAACAGAAATTGTAACATCGCATCAAAAGTCAGTA
ACCAACATTTTTCCACGAGAAGGTTGGTATGAGCAAGATCCACTTGAAATCATTAGTGTC
GTAAAGGAATGCATAGAGAAAGCAGTTGAAAAATTAATTGCTCTTGGTGGTTCAGCATCA
GACATTAAAGCTGTTGGAATTACAAATCAACGTGAAAGTACAGTAGTTTGGGATCCTGAA
ACAGGCGAGCCTTTTTATAATTGCATAATATGGAGTGACATTCGGACAACTTCAACTGTC
GATCAATTGCTTGAAAAAGTGCCCAACAAAACTCGCAACAAAAATTACCTCAAACCACTT
TGTGGTCTTCCATTGTCGACTTATTTTTCAGCTGTAAAGCTAAAATGGCTCTTGGACAAT
GCACAGTCAGTACAAGCAGCTGTAAGAAATGAAAAGCAAGTCATGTTTGGCACAATTGAT
ACTTGGTTAATTTGGAATCTTACTGATCGTATGCATGTGACTGATGTGACAAATGCAAGT
CGAACCATGCTTATGAATCTTGAAACACTCGAGTGGGATCCAATTTTAAAGAAATTTTTT
GACATTCCTGATTGCATTGAATTACCAACGATAAAATCGAGTTCAGAAATTTATGGAAAT
ATTGTTGATGGTTCTTTGAAAGGAATTCCAATTGCTGGATGTTTGGGTGATCAACAAGCA
GCTTTAGTAGGTCAAGGTTGCATGCAAATTGGTGAGGCAAAATGTACTTATGGCACTGGC
TGCTTTTTACTTTATTGTACTGGAAATCACAATGTTGATTCTGAGCATGGATTGTTGACT
ACAGTTGCTTATCAACTTGGTGATAGACATCCAGTTTATGCACTTGAAGGTTCAGTTGCT
GTCGCTGGTGCTGCTTTGACTTGGTTAAAAGATAACATTGAATTGATGCATGATTTTGAT
GAAATTGATGGACTTGTAAAATCAGTGAAGGACAATGGTGATGTTTATTTTGTTCCAGCC
TTTTCTGGATTGTTTGCACCTCATTGGGATGCTGAAGCAAGAGGAATTATTTGTGGAATA
ACTGAAGAAACACAGAGAGGACATATTGTTAGAGCTGCTTTGGAAAGTGTTTGCTTTCAG
GTCAAAGACATTCTTGATGCAATGAACCTCGAATGCGGCACACCATTATCAAAGCTCAAA
GTTGATGGTGGAATGACAAATAATAATTTTTTGATGCAAACACAAACTGATATAATTGGA
TTAGAGGTCATCAAGCCAGCAATGATTGAAACAACAAGTTTGGGAGCAGCAATGGTTGCT
GGTGCTGCTGTTGGTTTATGGAACATGGACTTGAAAGTTGAAAGCAACTCGAGAAATTTC
AAACCAAAAATTAGCGATTATGAAAGGGAAAATTGTTTCACGAAGTGGAAAATGGCAATT
GAAAGAAGTCTTGGATGGGATCAGAGTTAG
>g15492.t1 Gene=g15492 Length=509
MSSSKFGNLIGAIDEGTSSARFIIFKAETTEIVTSHQKSVTNIFPREGWYEQDPLEIISV
VKECIEKAVEKLIALGGSASDIKAVGITNQRESTVVWDPETGEPFYNCIIWSDIRTTSTV
DQLLEKVPNKTRNKNYLKPLCGLPLSTYFSAVKLKWLLDNAQSVQAAVRNEKQVMFGTID
TWLIWNLTDRMHVTDVTNASRTMLMNLETLEWDPILKKFFDIPDCIELPTIKSSSEIYGN
IVDGSLKGIPIAGCLGDQQAALVGQGCMQIGEAKCTYGTGCFLLYCTGNHNVDSEHGLLT
TVAYQLGDRHPVYALEGSVAVAGAALTWLKDNIELMHDFDEIDGLVKSVKDNGDVYFVPA
FSGLFAPHWDAEARGIICGITEETQRGHIVRAALESVCFQVKDILDAMNLECGTPLSKLK
VDGGMTNNNFLMQTQTDIIGLEVIKPAMIETTSLGAAMVAGAAVGLWNMDLKVESNSRNF
KPKISDYERENCFTKWKMAIERSLGWDQS
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g15492.t1 | Gene3D | G3DSA:3.30.420.40 | - | 3 | 265 | 9.0E-95 |
| 10 | g15492.t1 | Gene3D | G3DSA:3.30.420.40 | - | 266 | 509 | 7.3E-85 |
| 3 | g15492.t1 | PANTHER | PTHR10196 | SUGAR KINASE | 3 | 507 | 4.0E-248 |
| 4 | g15492.t1 | PANTHER | PTHR10196:SF82 | GH12641P | 3 | 507 | 4.0E-248 |
| 12 | g15492.t1 | PIRSF | PIRSF000538 | GlpK | 8 | 509 | 3.5E-138 |
| 2 | g15492.t1 | Pfam | PF00370 | FGGY family of carbohydrate kinases, N-terminal domain | 10 | 264 | 1.0E-70 |
| 1 | g15492.t1 | Pfam | PF02782 | FGGY family of carbohydrate kinases, C-terminal domain | 273 | 463 | 2.0E-60 |
| 8 | g15492.t1 | ProSitePatterns | PS00933 | FGGY family of carbohydrate kinases signature 1. | 148 | 160 | - |
| 7 | g15492.t1 | ProSitePatterns | PS00445 | FGGY family of carbohydrate kinases signature 2. | 375 | 395 | - |
| 6 | g15492.t1 | SUPERFAMILY | SSF53067 | Actin-like ATPase domain | 10 | 267 | 1.53E-71 |
| 5 | g15492.t1 | SUPERFAMILY | SSF53067 | Actin-like ATPase domain | 266 | 506 | 1.26E-70 |
| 11 | g15492.t1 | TIGRFAM | TIGR01311 | glycerol_kin: glycerol kinase | 9 | 506 | 4.6E-208 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0006072 | glycerol-3-phosphate metabolic process | BP |
| GO:0004370 | glycerol kinase activity | MF |
| GO:0016773 | phosphotransferase activity, alcohol group as acceptor | MF |
| GO:0005975 | carbohydrate metabolic process | BP |
KEGG
Orthology
- This transcript has been annotated with K00864 (glycerol kinase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
