General information for g15545.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Leucine-rich repeat-containing protein 15.
Parent gene
- The parent gene g15545 is located on chr_4: 5808670..5811083 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g15545 | g15545.t1 | isoform | g15545.t1 | 5807087 | 5808670 |
| chr_4 | g15545 | g15545.t1 | exon | g15545.t1.exon1 | 5807087 | 5807100 |
| chr_4 | g15545 | g15545.t1 | cds | g15545.t1.CDS1 | 5807087 | 5807100 |
| chr_4 | g15545 | g15545.t1 | exon | g15545.t1.exon2 | 5807212 | 5807276 |
| chr_4 | g15545 | g15545.t1 | cds | g15545.t1.CDS2 | 5807212 | 5807276 |
| chr_4 | g15545 | g15545.t1 | exon | g15545.t1.exon3 | 5807670 | 5808670 |
| chr_4 | g15545 | g15545.t1 | cds | g15545.t1.CDS3 | 5807670 | 5808670 |
| chr_4 | g15545 | g15545.t1 | TSS | g15545.t1 | NA | NA |
| chr_4 | g15545 | g15545.t1 | TTS | g15545.t1 | NA | NA |
Sequences
>g15545.t1 Gene=g15545 Length=1080
ATGAAAATTTTATTTTTTTATATTTTTATGAATTTGGGATATGTATTGTCATGTGATGAA
AAATGTTCTGAGAATTCAATTTCTTATCTAAATGGAGAGGAAGAACATGTAATAGGCTGC
TGTTTTACAACTAACGATGAAAGTTTAATGAATTGTGATTTTAGAAGTTTGTCTTTTGAT
GTTAGAGAAATCAACCAAACTCAAAAAACAAAAATTCATCCAAAATATTTCAATAAAGAA
ATTGAGTTCATGGACATCACAATTAAATGTGGAATCATATCTTGTATGAATCGAAGTTCA
ATTGAAAATCTGCCAATTAATGTTAATGAAATTTTTCCAAATTTAAAAGTTTATATGTTG
TTGAGAGGAAGTTTAAAAATTTTAAAATATGAACATTTTCAAGAACTTAAAAATTTGATC
TATTTGAATCTTCAAGAAAATTTTATTGAAAAAATTGAAGAAGAAACTTTTGATGATTTA
ATTGCTTTAAAATATTTGGATTTGAGCATGAATAAGTTGAAGAATTTCAATCCAAGAATT
TTCAAAAATAATTTGAATCTTTTACATTTAATTTTGTTTGAGAATCCACTTAAAACTTTT
CAGCCTGATCAATTTAAATTTCTTTCAAGTTTACATTTATTAAGTTTATGTGAAAATAAT
TTTACAACATTTGATATAAAAGTTTTTGAAAACTTAGTGAATTTAAAAGAATTGTGGCTT
TGTGAAAATCAAATAATTTCAATACCAGTTGGAATTTTTGATAATTTAGCTAATCTTGAA
TTTATATCTTTGGCCACAAATCAATTAACAACACTAGATGAAAATATTTTTGCAAAAAAT
TCAAACTTAAGACAAATGGAATTATGGGGCAATAAATTTACAAATTTAAGTTCAAAAATT
GTTGAAAATAAATCAAATTTGTTTCGTATTAGTTTTATTAACAACACTTGTATTAATACG
GAATACGGACAAGTAGATGTAAAAGAAAACTTGACAAAAGAAGAGAAATATCAAATTCAA
AATGACATTGAAAACTGTTGCACACAAAAAACAGTTCAAAATTATGATTGTGGATTATAA
>g15545.t1 Gene=g15545 Length=359
MKILFFYIFMNLGYVLSCDEKCSENSISYLNGEEEHVIGCCFTTNDESLMNCDFRSLSFD
VREINQTQKTKIHPKYFNKEIEFMDITIKCGIISCMNRSSIENLPINVNEIFPNLKVYML
LRGSLKILKYEHFQELKNLIYLNLQENFIEKIEEETFDDLIALKYLDLSMNKLKNFNPRI
FKNNLNLLHLILFENPLKTFQPDQFKFLSSLHLLSLCENNFTTFDIKVFENLVNLKELWL
CENQIISIPVGIFDNLANLEFISLATNQLTTLDENIFAKNSNLRQMELWGNKFTNLSSKI
VENKSNLFRISFINNTCINTEYGQVDVKENLTKEEKYQIQNDIENCCTQKTVQNYDCGL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 10 | g15545.t1 | Gene3D | G3DSA:3.80.10.10 | Ribonuclease Inhibitor | 40 | 229 | 8.1E-23 |
| 9 | g15545.t1 | Gene3D | G3DSA:3.80.10.10 | Ribonuclease Inhibitor | 230 | 356 | 3.1E-16 |
| 4 | g15545.t1 | PANTHER | PTHR24373:SF279 | - | 82 | 252 | 1.5E-34 |
| 6 | g15545.t1 | PANTHER | PTHR24373 | SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN | 82 | 252 | 1.5E-34 |
| 3 | g15545.t1 | PANTHER | PTHR24373:SF279 | - | 187 | 317 | 1.5E-34 |
| 5 | g15545.t1 | PANTHER | PTHR24373 | SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN | 187 | 317 | 1.5E-34 |
| 2 | g15545.t1 | Pfam | PF13855 | Leucine rich repeat | 114 | 173 | 7.1E-10 |
| 1 | g15545.t1 | Pfam | PF13855 | Leucine rich repeat | 234 | 293 | 3.1E-10 |
| 12 | g15545.t1 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 17 | - |
| 13 | g15545.t1 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 2 | - |
| 14 | g15545.t1 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 3 | 12 | - |
| 15 | g15545.t1 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 13 | 17 | - |
| 11 | g15545.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 18 | 359 | - |
| 25 | g15545.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 138 | 159 | 7.242 |
| 21 | g15545.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 162 | 183 | 6.38 |
| 27 | g15545.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 186 | 207 | 5.071 |
| 24 | g15545.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 210 | 233 | 4.693 |
| 22 | g15545.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 234 | 255 | 7.142 |
| 23 | g15545.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 258 | 279 | 6.249 |
| 26 | g15545.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 282 | 303 | 4.994 |
| 19 | g15545.t1 | SMART | SM00369 | LRR_typ_2 | 136 | 159 | 1.1 |
| 16 | g15545.t1 | SMART | SM00369 | LRR_typ_2 | 160 | 183 | 3.4 |
| 18 | g15545.t1 | SMART | SM00369 | LRR_typ_2 | 208 | 231 | 17.0 |
| 20 | g15545.t1 | SMART | SM00369 | LRR_typ_2 | 232 | 255 | 0.0094 |
| 17 | g15545.t1 | SMART | SM00369 | LRR_typ_2 | 256 | 279 | 0.05 |
| 7 | g15545.t1 | SUPERFAMILY | SSF52058 | L domain-like | 93 | 318 | 8.26E-38 |
| 8 | g15545.t1 | SignalP_EUK | SignalP-noTM | SignalP-noTM | 1 | 17 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005515 | protein binding | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed