General information for g15566.t2
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as cAMP-dependent protein kinase catalytic subunit 3.
Parent gene
- The parent gene g15566 is located on chr_4: 5882942..5886250 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g15566 | g15566.t2 | isoform | g15566.t2 | 5882942 | 5885462 |
| chr_4 | g15566 | g15566.t2 | exon | g15566.t2.exon1 | 5882942 | 5883032 |
| chr_4 | g15566 | g15566.t2 | cds | g15566.t2.CDS1 | 5882942 | 5883032 |
| chr_4 | g15566 | g15566.t2 | exon | g15566.t2.exon2 | 5884613 | 5884781 |
| chr_4 | g15566 | g15566.t2 | cds | g15566.t2.CDS2 | 5884613 | 5884781 |
| chr_4 | g15566 | g15566.t2 | exon | g15566.t2.exon3 | 5884837 | 5884873 |
| chr_4 | g15566 | g15566.t2 | cds | g15566.t2.CDS3 | 5884837 | 5884873 |
| chr_4 | g15566 | g15566.t2 | exon | g15566.t2.exon4 | 5884930 | 5885093 |
| chr_4 | g15566 | g15566.t2 | cds | g15566.t2.CDS4 | 5884930 | 5885093 |
| chr_4 | g15566 | g15566.t2 | exon | g15566.t2.exon5 | 5885151 | 5885462 |
| chr_4 | g15566 | g15566.t2 | cds | g15566.t2.CDS5 | 5885151 | 5885460 |
| chr_4 | g15566 | g15566.t2 | TSS | g15566.t2 | NA | NA |
| chr_4 | g15566 | g15566.t2 | TTS | g15566.t2 | NA | NA |
Sequences
>g15566.t2 Gene=g15566 Length=773
ATGTCATCACAATTTTTCACATTAAATTGTAAAACAAAACCAGAACAATCATCGACAGAA
GAAAAGTCTTTCGATGTTTTAAAAATTGTCGGCACCGGCACATTTGGTAAAGTGGTGCTT
TGCAAAGAGATAAATGAAAATGCTTTCTACGCCATCAAAGTTTTGTCGATTCATCACATC
GTGAATAAAAAGCAAATCGAACATGTCAAAAGTGAAAGGAACATATTACTTGAAATTAGT
CATCCATTCATTGTGTCAATGCGATTTTTTGCTCGAGATCTTAAAAATATTTATTTGGGT
TTTGAATTCATTGATGGTGGCGAATTATTTTCATATTTAAGGAAAATCAAAAAATTTGAC
AGTCCAACAGCAAATTTTTATGCTCGTGAAATTCTTTTGGCTCTGGAATATTTGCATTCA
TTATCAATTATTTATCGTGATTTGAAACCTGAAAATTTGATGCTTGATCATGAAGGACAT
TTAAAAATCACAGACTTTGGCTTTAGTAAAAAACTTAAAGATCGAACGTGGACACTTTGT
GGCACAATGGAATATCTTGCACCAGAAATTATTCAAAATCGAGGACATAACAAAGGTGTT
GATTTTTGGGCTTTTGGAATTTTGATTTTTGAAATGTTAGTTGGAAAACCGCCATTTAGA
GGCGAAGATTTTTATGCAGTTCAAGATTTAATATTGAACAGAAAAATTGAATGGCCAAAG
AATTTTGATTTGGTTGCCAAGGATCTCATTAAGAAGCTTTTGACTGTTGATAG
>g15566.t2 Gene=g15566 Length=257
MSSQFFTLNCKTKPEQSSTEEKSFDVLKIVGTGTFGKVVLCKEINENAFYAIKVLSIHHI
VNKKQIEHVKSERNILLEISHPFIVSMRFFARDLKNIYLGFEFIDGGELFSYLRKIKKFD
SPTANFYAREILLALEYLHSLSIIYRDLKPENLMLDHEGHLKITDFGFSKKLKDRTWTLC
GTMEYLAPEIIQNRGHNKGVDFWAFGILIFEMLVGKPPFRGEDFYAVQDLILNRKIEWPK
NFDLVAKDLIKKLLTVD
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 5 | g15566.t2 | Gene3D | G3DSA:3.30.200.20 | Phosphorylase Kinase; domain 1 | 23 | 107 | 7.3E-94 |
| 6 | g15566.t2 | Gene3D | G3DSA:1.10.510.10 | Transferase(Phosphotransferase) domain 1 | 108 | 257 | 7.3E-94 |
| 2 | g15566.t2 | PANTHER | PTHR24353:SF117 | UT01108P-RELATED | 16 | 257 | 5.7E-104 |
| 3 | g15566.t2 | PANTHER | PTHR24353 | CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE | 16 | 257 | 5.7E-104 |
| 7 | g15566.t2 | PIRSF | PIRSF000654 | ILK | 5 | 252 | 3.6E-32 |
| 1 | g15566.t2 | Pfam | PF00069 | Protein kinase domain | 25 | 257 | 1.8E-65 |
| 9 | g15566.t2 | ProSitePatterns | PS00107 | Protein kinases ATP-binding region signature. | 30 | 53 | - |
| 8 | g15566.t2 | ProSitePatterns | PS00108 | Serine/Threonine protein kinases active-site signature. | 143 | 155 | - |
| 11 | g15566.t2 | ProSiteProfiles | PS50011 | Protein kinase domain profile. | 24 | 257 | 45.842 |
| 10 | g15566.t2 | SMART | SM00220 | serkin_6 | 24 | 257 | 1.2E-77 |
| 4 | g15566.t2 | SUPERFAMILY | SSF56112 | Protein kinase-like (PK-like) | 21 | 257 | 3.1E-80 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005524 | ATP binding | MF |
| GO:0004672 | protein kinase activity | MF |
| GO:0006468 | protein phosphorylation | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed