General information for g15566.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as cAMP-dependent protein kinase catalytic subunit 3.
Parent gene
- The parent gene g15566 is located on chr_4: 5882942..5886250 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g15566 | g15566.t3 | isoform | g15566.t3 | 5882942 | 5886250 |
| chr_4 | g15566 | g15566.t3 | exon | g15566.t3.exon1 | 5882942 | 5883032 |
| chr_4 | g15566 | g15566.t3 | cds | g15566.t3.CDS1 | 5882942 | 5883032 |
| chr_4 | g15566 | g15566.t3 | exon | g15566.t3.exon2 | 5884613 | 5884775 |
| chr_4 | g15566 | g15566.t3 | cds | g15566.t3.CDS2 | 5884613 | 5884775 |
| chr_4 | g15566 | g15566.t3 | exon | g15566.t3.exon3 | 5884837 | 5884873 |
| chr_4 | g15566 | g15566.t3 | cds | g15566.t3.CDS3 | 5884837 | 5884873 |
| chr_4 | g15566 | g15566.t3 | exon | g15566.t3.exon4 | 5884930 | 5885093 |
| chr_4 | g15566 | g15566.t3 | cds | g15566.t3.CDS4 | 5884930 | 5885093 |
| chr_4 | g15566 | g15566.t3 | exon | g15566.t3.exon5 | 5885151 | 5885462 |
| chr_4 | g15566 | g15566.t3 | cds | g15566.t3.CDS5 | 5885151 | 5885462 |
| chr_4 | g15566 | g15566.t3 | exon | g15566.t3.exon6 | 5885845 | 5885947 |
| chr_4 | g15566 | g15566.t3 | cds | g15566.t3.CDS6 | 5885845 | 5885947 |
| chr_4 | g15566 | g15566.t3 | exon | g15566.t3.exon7 | 5886134 | 5886250 |
| chr_4 | g15566 | g15566.t3 | cds | g15566.t3.CDS7 | 5886134 | 5886250 |
| chr_4 | g15566 | g15566.t3 | TSS | g15566.t3 | NA | NA |
| chr_4 | g15566 | g15566.t3 | TTS | g15566.t3 | NA | NA |
Sequences
>g15566.t3 Gene=g15566 Length=987
ATGTCATCACAATTTTTCACATTAAATTGTAAAACAAAACCAGAACAATCATCGACAGAA
GAAAAGTCTTTCGATGTTTTAAAAATTGTCGGCACCGGCACATTTGGTAAAGTGGTGCTT
TGCAAAGAGATAAATGAAAATGCTTTCTACGCCATCAAAGTTTTGTCGATTCATCACATC
GTGAATAAAAAGCAAATCGAACATGTCAAAAGTGAAAGGAACATATTACTTGAAATTAGT
CATCCATTCATTGTGCGATTTTTTGCTCGAGATCTTAAAAATATTTATTTGGGTTTTGAA
TTCATTGATGGTGGCGAATTATTTTCATATTTAAGGAAAATCAAAAAATTTGACAGTCCA
ACAGCAAATTTTTATGCTCGTGAAATTCTTTTGGCTCTGGAATATTTGCATTCATTATCA
ATTATTTATCGTGATTTGAAACCTGAAAATTTGATGCTTGATCATGAAGGACATTTAAAA
ATCACAGACTTTGGCTTTAGTAAAAAACTTAAAGATCGAACGTGGACACTTTGTGGCACA
ATGGAATATCTTGCACCAGAAATTATTCAAAATCGAGGACATAACAAAGGTGTTGATTTT
TGGGCTTTTGGAATTTTGATTTTTGAAATGTTAGTTGGAAAACCGCCATTTAGAGGCGAA
GATTTTTATGCAGTTCAAGATTTAATATTGAACAGAAAAATTGAATGGCCAAAGAATTTT
GATTTGGTTGCCAAGGATCTCATTAAGAAGCTTTTGACTGTTGATAGAACCAAAAGATTG
GGATGCATGCGTAATGGTGCAAAAGATATAAAATCACACAGATGGTTTAGTGAAGTTAAT
TGGACTGATGTTTATAACAGAAAATATGATCCTCCAATCAAACCAAAAACAGGAACTTTA
ACAACAAATTTTGAAGATTATGGTGATAATTTTGGTGATGATGAAGAATATGAGCTAGAA
GATAATGACATCTTCAATGATTTTTAA
>g15566.t3 Gene=g15566 Length=328
MSSQFFTLNCKTKPEQSSTEEKSFDVLKIVGTGTFGKVVLCKEINENAFYAIKVLSIHHI
VNKKQIEHVKSERNILLEISHPFIVRFFARDLKNIYLGFEFIDGGELFSYLRKIKKFDSP
TANFYAREILLALEYLHSLSIIYRDLKPENLMLDHEGHLKITDFGFSKKLKDRTWTLCGT
MEYLAPEIIQNRGHNKGVDFWAFGILIFEMLVGKPPFRGEDFYAVQDLILNRKIEWPKNF
DLVAKDLIKKLLTVDRTKRLGCMRNGAKDIKSHRWFSEVNWTDVYNRKYDPPIKPKTGTL
TTNFEDYGDNFGDDEEYELEDNDIFNDF
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g15566.t3 | Gene3D | G3DSA:3.30.200.20 | Phosphorylase Kinase; domain 1 | 23 | 304 | 7.9E-110 |
| 8 | g15566.t3 | Gene3D | G3DSA:1.10.510.10 | Transferase(Phosphotransferase) domain 1 | 106 | 296 | 7.9E-110 |
| 2 | g15566.t3 | PANTHER | PTHR24353 | CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE | 12 | 328 | 1.7E-125 |
| 1 | g15566.t3 | Pfam | PF00069 | Protein kinase domain | 25 | 276 | 2.4E-68 |
| 6 | g15566.t3 | ProSitePatterns | PS00107 | Protein kinases ATP-binding region signature. | 30 | 53 | - |
| 5 | g15566.t3 | ProSitePatterns | PS00108 | Serine/Threonine protein kinases active-site signature. | 141 | 153 | - |
| 10 | g15566.t3 | ProSiteProfiles | PS50011 | Protein kinase domain profile. | 24 | 276 | 45.333 |
| 9 | g15566.t3 | ProSiteProfiles | PS51285 | AGC-kinase C-terminal domain profile. | 277 | 328 | 11.146 |
| 4 | g15566.t3 | SMART | SM00220 | serkin_6 | 24 | 276 | 4.0E-93 |
| 3 | g15566.t3 | SUPERFAMILY | SSF56112 | Protein kinase-like (PK-like) | 21 | 300 | 1.62E-88 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005524 | ATP binding | MF |
| GO:0004674 | protein serine/threonine kinase activity | MF |
| GO:0004672 | protein kinase activity | MF |
| GO:0006468 | protein phosphorylation | BP |
KEGG
Orthology
- This transcript has been annotated with K19584 (protein kinase X)
Pathway
This gene does not belong to any pathways.
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed