General information for g15750.t2
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Adenylosuccinate lyase.
Parent gene
- The parent gene g15750 is located on chr_4: 6651902..6652768 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g15750 | g15750.t2 | TSS | g15750.t2 | 6651125 | 6651125 |
| chr_4 | g15750 | g15750.t2 | isoform | g15750.t2 | 6651902 | 6652768 |
| chr_4 | g15750 | g15750.t2 | exon | g15750.t2.exon1 | 6651902 | 6652768 |
| chr_4 | g15750 | g15750.t2 | cds | g15750.t2.CDS1 | 6652038 | 6652703 |
| chr_4 | g15750 | g15750.t2 | TTS | g15750.t2 | 6652762 | 6652762 |
Sequences
>g15750.t2 Gene=g15750 Length=867
TAAACAACTTGATGCAAAAGTAACTGAACTTGCTGGATTTAGCAAGAGTTATGCTGTTAC
AGGACAAACTTACACTCGAAAAGTTGATGTCGATGTTGTATCAGCAATTGCAAGTCTTGG
ATCTTCTGTTCATAAAATGTGCAGTGATTTACGCTTGTTGGCATCAATGAAGGAAGTTGA
GGAGCCTTTTGAGACAACACAAATTGGATCATCAGCAATGCCTTATAAACGTAATCCAAT
GCGTTCTGAAAGATGTTGTGCACTTGCCCGTCATTTGATTACGCTTCAATCAAATGCAGC
CAACACTCATGCAACACAATGGATGGAACGAACACTTGATGATTCTGCAAATCGTAGATT
GACACTTTCTGAAAGTTTTCTTGCTGCCGATGCGTGCCTTTTGACACTTTTGAATATTTC
TCAAGGAATGGTTGTTTATCCGAAAGTTATTGAACGCCATATTTTGCAAGAATTGCCATT
TATGGCTGCTGAAAATGTCATTATGGCAATGGTCAAAGCTGGTGGTGATCGTCAAGTGTG
CCATGAGAAAATTCGAGTTCTATCACATGAAGCTGGTGCACAAGTTAAGCAACATGGAAA
AGACAACGACTTAGTTGAAAGAATCAAAGCTGACAAATATTTTGAGCCAATTTTGGGACA
ACTTGAGCACATTTTAGATGCAAAAACTTTCACTGGAAGAGCTGGAGAACAAGTTGTTGA
ATTTTATGAGGAAGAAGTCAAAGAAATTTTGGAAAAATATGCTGACAAAATTCAAACTAA
AGAAGTTAAATTGGAAATTTAAATAAAAATGTAGCAAAGCTAGAAAAATTTTCCTAAATA
AAAATTTCTTTTATTTTGAAAAGTTTT
>g15750.t2 Gene=g15750 Length=221
MCSDLRLLASMKEVEEPFETTQIGSSAMPYKRNPMRSERCCALARHLITLQSNAANTHAT
QWMERTLDDSANRRLTLSESFLAADACLLTLLNISQGMVVYPKVIERHILQELPFMAAEN
VIMAMVKAGGDRQVCHEKIRVLSHEAGAQVKQHGKDNDLVERIKADKYFEPILGQLEHIL
DAKTFTGRAGEQVVEFYEEEVKEILEKYADKIQTKEVKLEI
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g15750.t2 | Coils | Coil | Coil | 194 | 214 | - |
| 8 | g15750.t2 | Gene3D | G3DSA:1.20.200.10 | Fumarase/aspartase (Central domain) | 1 | 111 | 2.0E-36 |
| 7 | g15750.t2 | Gene3D | G3DSA:1.10.40.30 | - | 112 | 185 | 1.4E-28 |
| 3 | g15750.t2 | PANTHER | PTHR43172 | ADENYLOSUCCINATE LYASE | 1 | 211 | 6.7E-84 |
| 1 | g15750.t2 | Pfam | PF00206 | Lyase | 1 | 41 | 2.0E-7 |
| 2 | g15750.t2 | Pfam | PF10397 | Adenylosuccinate lyase C-terminus | 114 | 194 | 1.8E-16 |
| 6 | g15750.t2 | ProSitePatterns | PS00163 | Fumarate lyases signature. | 24 | 33 | - |
| 5 | g15750.t2 | SMART | SM00998 | ADSL_C_2 | 113 | 197 | 1.4E-23 |
| 4 | g15750.t2 | SUPERFAMILY | SSF48557 | L-aspartase-like | 1 | 197 | 1.73E-41 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0003824 | catalytic activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
