Gene loci information

Transcript annotation

  • This transcript has been annotated as Aldo-keto reductase family 1 member B1.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_4 g15759 g15759.t13 TTS g15759.t13 6681153 6681153
chr_4 g15759 g15759.t13 isoform g15759.t13 6681640 6682422
chr_4 g15759 g15759.t13 exon g15759.t13.exon1 6681640 6681990
chr_4 g15759 g15759.t13 cds g15759.t13.CDS1 6681740 6681990
chr_4 g15759 g15759.t13 exon g15759.t13.exon2 6682046 6682422
chr_4 g15759 g15759.t13 cds g15759.t13.CDS2 6682046 6682370
chr_4 g15759 g15759.t13 TSS g15759.t13 NA NA

Sequences

>g15759.t13 Gene=g15759 Length=728
ATTAAAATTTTTAAAACTTGATTATTTGGATCTTTACTTGATTCATTGGCCAATGGGTTA
TGCTTATTTGAATAATGGTGAAACATTATTCCCTAAAAATGAGAAAGAAGAATGGATTTT
CTCAGAAGTTGATTATGTCGACACATGGAAAGCAATGGAGGAATTAGTTGAAGCTGGATT
AGTAAAATCAATTGGTCTGAGCAATTTCAATTCAAAACAAATCGAACGTGTACTGGCTGT
AGCTAAAATCAAACCAGTAATGAACCAAGTTGAATGCCATCCTTATTTGACACAGAAGAA
ATTAATTGAATTCTGTCGTAGTAAAGGCATTGCTGTTACTGCATATTCACCACTGGGGTC
TAACGACCGTCCTTGGGCAAAACCAGATGATCCACAGCTCATGGATGATCCAAGAATTGT
TGCTTTAGCAGAAAAGTATCAAAAAACTCCAGCTCAAATTCTTATTCGGTATCAAATTCA
ACGTAGAGTTGTTGTCATTCCTAAATCAGTCACAAAATCAAGAATCATTAGCAACTTTGA
TGTTTTTGGCTTTGAATTATCTTCTGAAGATATTGCAAGTATCGATAGCATTGACTGCAA
TGGAAGATTGTGTCATTTGAATTGGTAAGATTAAAAAAATTTTTACTGAACTTTTATTAA
GTTTTTTGTATTTTTTCAGGGTTTCTCATCATCCACATTATCCATTTGGAACAGACGTTG
AATTTTAA

>g15759.t13 Gene=g15759 Length=191
MGYAYLNNGETLFPKNEKEEWIFSEVDYVDTWKAMEELVEAGLVKSIGLSNFNSKQIERV
LAVAKIKPVMNQVECHPYLTQKKLIEFCRSKGIAVTAYSPLGSNDRPWAKPDDPQLMDDP
RIVALAEKYQKTPAQILIRYQIQRRVVVIPKSVTKSRIISNFDVFGFELSSEDIASIDSI
DCNGRLCHLNW

Protein features from InterProScan

Transcript Database ID Name Start End E.value
10 g15759.t13 Gene3D G3DSA:3.20.20.100 - 3 191 1.2E-78
2 g15759.t13 PANTHER PTHR11732:SF402 ALDO-KETO REDUCTASE FAMILY 1 MEMBER A1-A 7 188 3.8E-77
3 g15759.t13 PANTHER PTHR11732 ALDO/KETO REDUCTASE 7 188 3.8E-77
5 g15759.t13 PRINTS PR00069 Aldo-keto reductase signature 35 52 7.5E-34
4 g15759.t13 PRINTS PR00069 Aldo-keto reductase signature 69 98 7.5E-34
6 g15759.t13 PRINTS PR00069 Aldo-keto reductase signature 116 140 7.5E-34
1 g15759.t13 Pfam PF00248 Aldo/keto reductase family 21 180 1.2E-32
8 g15759.t13 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 35 52 -
9 g15759.t13 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 149 164 -
7 g15759.t13 SUPERFAMILY SSF51430 NAD(P)-linked oxidoreductase 7 188 5.11E-59

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0047834 D-threo-aldose 1-dehydrogenase activity MF
GO:0055114 NA NA
GO:0016491 oxidoreductase activity MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values